United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Celebrity Cruises, Celebrity Reflection

4 Night - Key West & Bahamas Cruise
Starting in Fort Lauderdale, Florida, Key West, Florida, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jul 20, Aug 17, Aug 31, 2027: Jan 4, Jan 18, Mar 15, Jun 21, Aug 2, Dec 6, Dec 20, Dec 27, 2028: Mar 13, Mar 27, More...

Cunard Line, Queen Elizabeth

10 Night - Alaska Roundtrip from Seattle
Starting in Seattle, WA, Ketchikan, AK, Endicott Arm, AK, (Scenic Cruising), Juneau, AK, Skagway, AK, Glacier Bay, AK, (Scenic Cruising), Wrangell, AK, Victoria CA, Canada, Seattle, WA
2026 Sails: Jul 20, More...

Disney Cruise Line, Disney Wish

4 Night - Bahamian Cruise from Port Canaveral
Starting in Port Canaveral, Nassau, Disney Lookout Cay, Port Canaveral
2026 Sails: Jul 20, More...

Lindblad Expeditions, National Geographic Sea Bird

10 Night - Alaska Epic Escape : Complete Inside Passage
Starting in Ketchikan / Embark Ship, Misty Fjords National Monument, Wrangell, Sumner Strait, LeConte Bay, Juneau, Endicott Arm, Haines, Icy Strait and the Inian Islands, Baranof or Chichagof Island, Sitka / Disembark Ship
2026 Sails: Jul 20, Aug 9, More...

Lindblad Expeditions Tours, National Geographic Sea Bird Tours

5 Night - Alaska Escape : Leconte Bay, Wrangell and Misty Fjords
Starting in Ketchikan / Embark Ship, Behm Canal / Misty Fjords National Monument, Wrangell, Sumner Strait, LeConte Bay, Juneau
2026 Sails: Jul 20, Aug 9, More...

Margaritaville at Sea, Margaritaville Paradise

4 Night - Bahamas Duo
Starting in Port of Palm Beach, Nassau, Bahamas, Freeport, Grand Bahama, Port of Palm Beach
2026 Sails: Jul 20, Aug 10, Aug 17, Sep 7, Nov 30, Dec 24, Dec 28, 2027: Jan 4, Mar 15, Apr 26, Jun 21, Jul 5, Aug 2, Sep 6, Oct 18, Dec 23, More...

MSC Cruises, MSC Seaside

4 Night - Caribbean and Antilles
Starting in Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Jul 20, Jul 27, Aug 3, Aug 10, Aug 17, Aug 24, Aug 31, Sep 7, Sep 14, Sep 21, Sep 28, Oct 5, Oct 12, Oct 19, Oct 26, More...

MSC Cruises, MSC Seaside

7 Night - Caribbean and Antilles
Starting in Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Jul 20, Jul 27, Aug 10, Aug 17, Aug 24, Aug 31, Sep 7, Sep 14, Sep 21, Sep 28, Oct 5, Oct 12, Oct 19, More...

Norwegian Cruise Line, Norwegian Getaway

Deal link -> Special

4 Night - Bahamas - Short
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Nassau, Bahamas, Miami, Fl
2026 Sails: Jul 20, Jul 27, Aug 10, More...

Norwegian Cruise Line, Norwegian Jade

7 Night - Alaska - Southbound Whittier
Starting in Whittier, Ak, Cruise Hubbard Glacier, Ak, Icy Strait Point, Ak, Juneau, Ak, Skagway, Ak, Ketchikan (Ward Cove), Ak, Cruise Inside Passage Al, Vancouver, Canada
2026 Sails: Jul 20, Aug 3, Aug 17, Aug 31, More...

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United States Cruise Departures