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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.




MS Roald Amundsen Cruises8 Night - West Coast Highlights from San Diego to Vancouver
Starting in San Diego; with stops in Los Angeles; Monterey; San Francisco; Seattle; Vancouver
2020 Sails: May 10, More...
RCL Serenade of the Seas Cruise Ship7 Night - Pacific Coastal Cruise
Starting in San Diego with stops in San Francisco, Astoria, Seattle, Vancouver
2020 Sails: May 19, More...
Star Breeze Cruises10 Night - San Diego to Vancouver - Star Breeze -
Starting in San Diego with stops in Santa Barbara, Monterey, San Francisco, Portland, Seattle, Victoria, Vancouver
2020 Sails: Jun 16, More...
Disney Wonder Cruise Ship5 Night - Baja Cruise from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2020 Sails: Sep 18, Nov 1, 2021: Mar 19, Mar 28, Apr 2, Apr 18, May 7, More...
Disney Wonder Cruise Ship4 Night - Halloween on the High Seas Baja Cruise from San Diego
Starting in San Diego; with stops in Cabo San Lucas
2020 Sails: Sep 23, Oct 12, Oct 28, More...
HAL Maasdam Cruise Ship12 Night - Mexico & Sea of Cortez
Starting in San Diego with stops in Cruising Bahia Magdalena, Cabo San Lucas, Pichilingue, Loreto, Guaymas, Topolobampo, Mazatlan, Puerto Vallarta
2020 Sails: Sep 25, More...
Disney Wonder Cruise Ship7 Night - Halloween on the High Seas Mexican Riviera Cruise from San Diego
Starting in San Diego; with stops in Cabo San Lucas; Mazatlán; Puerto Vallarta
2020 Sails: Sep 27, More...
Scenic Eclipse Cruises13 Night - Baja to Costa Rica: Whales and Wilderness: San Diego to San Jose aboard Scenic Eclipse (Combo)
Starting in San Diego with stops in La Paz, Isla Cerralvo, Puerto Vallarta, Acapulco, Puerto Quetzal, Acajutla, Corinto, Bahia Culebra, San Jose
2020 Sails: Sep 27, More...
Scenic Eclipse Cruises24 Night - Ultimate Baja, Costa Rica and Peru Adventure: San Diego to Lima aboard Scenic Eclipse (Combo)
Starting in San Diego with stops in La Paz, Isla Cerralvo, Puerto Vallarta, Acapulco, Puerto Quetzal, Acajutla, Corinto, Bahia Culebra, Puerto Caldera, Curu National Park, Quepos, Darien National Park, Utria National Park, Isla de la Plata, Salaverry, Isla Guanape, Lima
2020 Sails: Sep 27, More...
HAL Eurodam Cruise Ship15 Night - Panama Canal
Starting in San Diego with stops in Manzanillo, Huatulco, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Fort Lauderdale
2020 Sails: Oct 3, More...


San Diego Cruise Departures

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