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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



HAL Zuiderdam Cruise Ship7 Night - Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2021 Sails: Sep 25, Oct 2, Oct 9, More...
Disney Wonder Cruise Ship4 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; San Diego, California
2021 Sails: Oct 1, Oct 11, Oct 18, Oct 22, Oct 27, Oct 31, 2022: Sep 28, More...
Disney Wonder Cruise Ship3 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; San Diego, California
2021 Sails: Oct 5, Oct 8, Oct 15, 2022: Oct 9, More...
HAL Nieuw Amsterdam Cruise Ship17 Night - Panama Canal
Starting in San Diego with stops in Cabo San Lucas, Puerto Vallarta, Manzanillo, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Half Moon Cay, Fort Lauderdale
2021 Sails: Oct 6, More...
HAL Koningsdam Cruises7 Night - Classic California Coast
Starting in San Diego with stops in Avalon, Santa Barbara, San Francisco, Ensenada
2021 Sails: Oct 10, More...
Celebrity Millennium Cruise Ship8 Night - Pacific Coastal From San Diego, California - Onboard Celebrity Millennium
Starting in San Diego with stops in San Francisco, Catalina Island, Ensenada
2021 Sails: Oct 11, More...
HAL Zuiderdam Cruise Ship7 Night - Classic California Coast
Starting in San Diego with stops in Ensenada, San Francisco, Santa Barbara, Avalon
2021 Sails: Oct 16, Oct 23, More...
HAL Koningsdam Cruises7 Night - Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2021 Sails: Oct 17, More...
Celebrity Millennium Cruise Ship8 Night - Pacific Coastal From San Diego, California - Onboard Celebrity Millennium
Starting in San Diego with stops in San Francisco, Catalina Island, Ensenada
2021 Sails: Oct 19, More...
HAL Koningsdam Cruises7 Night - Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2021 Sails: Oct 24, Nov 14, Nov 28, Dec 12, More...


San Diego Cruise Departures

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