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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Disney Wonder Cruise Ship5 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2021 Sails: Apr 2, Apr 18, May 7, Sep 19, Sep 26, 2022: Mar 20, Mar 25, Apr 3, Apr 8, More...
Disney Wonder Cruise Ship4 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; San Diego, California
2021 Sails: Apr 7, Apr 26, May 3, 2022: Apr 13, Apr 17, More...
Disney Wonder Cruise Ship7 Night - Mexican Riviera Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Mazatlán, Mexico; Puerto Vallarta, Mexico; San Diego, California
2021 Sails: Apr 11, More...
Disney Wonder Cruise Ship3 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; San Diego, California
2021 Sails: Apr 23, Apr 30, More...
Disney Wonder Cruise Ship5 Night - Pacific Coast Cruise from San Diego to Vancouver
Starting in San Diego, California; with stops in San Francisco, California; Victoria, Canada; Vancouver, Canada
2021 Sails: May 12, 2022: Apr 21, More...
Disney Wonder Cruise Ship2 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico
2021 Sails: Sep 17, Sep 24, 2022: Mar 18, More...
Disney Wonder Cruise Ship7 Night - Halloween on the High Seas Mexican Riviera Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Mazatlán, Mexico; Puerto Vallarta, Mexico; San Diego, California
2021 Sails: Oct 1, More...
Disney Wonder Cruise Ship3 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; San Diego, California
2021 Sails: Oct 8, Oct 15, More...
Disney Wonder Cruise Ship4 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; San Diego, California
2021 Sails: Oct 11, Oct 18, Oct 27, More...
HAL Oosterdam Cruise Ship30 Night - South Pacific Crossing
Starting in San Diego with stops in Honolulu, Lahaina, Kona, Scenic cruising Kilauea Volcano, Hilo, Cross International Dateline, Kiritimati, Crossing the Equator, Bora Bora, Moorea, Papeete, Rarotonga, Vava u, Nuku Alofa, Cascade, Sydney
2021 Sails: Oct 20, More...


San Diego Cruise Departures

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