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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Disney Wonder Cruise Ship2 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; San Diego, California
2021 Sails: Sep 17, Sep 24, 2022: Mar 18, More...
Disney Wonder Cruise Ship5 Night - Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2021 Sails: Sep 19, Sep 26, 2022: Mar 20, Mar 25, Apr 3, Apr 8, More...
Disney Wonder Cruise Ship7 Night - Halloween on the High Seas Mexican Riviera Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Mazatlán, Mexico; Puerto Vallarta, Mexico; San Diego, California
2021 Sails: Oct 1, More...
Disney Wonder Cruise Ship3 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Ensenada, Mexico; San Diego, California
2021 Sails: Oct 8, Oct 15, More...
Celebrity Millennium Cruise Ship8 Night - California Coastal Cruise from San Diego, California - Onboard Celebrity Millennium
Starting in San Diego with stops in San Francisco, Catalina Island, Santa Barbara, Ensenada
2021 Sails: Oct 11, More...
Disney Wonder Cruise Ship4 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; San Diego, California
2021 Sails: Oct 11, Oct 18, Oct 27, More...
Disney Wonder Cruise Ship5 Night - Halloween on the High Seas Baja Cruise Roundtrip from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2021 Sails: Oct 22, Oct 31, More...
HAL Koningsdam Cruises7 Night - Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2021 Sails: Oct 24, More...
Celebrity Millennium Cruise Ship15 Night - Panama Canal Eastbound Cruise from San Diego, California - Onboard Celebrity Millennium
Starting in San Diego with stops in Cabo San Lucas, Puerto Vallarta, Puerto Quetzal, Puntarenas, Panama Canal, Colon, Cartagena, Fort Lauderdale
2021 Sails: Oct 27, More...
HAL Zuiderdam Cruise Ship7 Night - Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2021 Sails: Oct 30, More...


San Diego Cruise Departures

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