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San Diego Cruise Departures

Cruises that depart from North America: United States: California: San Diego

Cruises that visit San Diego

Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.




Le Soleal Cruises13 Night The Sea of Cortez from San Diego to Puerto Quetzal
Starting in San Diego; with stops in Cabo San Lucas; Coronado Island; Danzante Island; Monserrat Island; Puerto Agua Verde; Punta Colorada, Isla San Jose; Bahia Amortajada, Isla San Jose; Los Islotes; Isla Partida; Espíritu Santo Island; Cerralvo Island; Huatulco; Puerto Quetzal
2019 Sails: Sep 10, More...
HAL Amsterdam Cruise Ship28 Night Incan Empires
Starting in San Diego with stops in Cabo San Lucas, Huatulco, Fuerte Amador, Manta, Salaverry, Callao, Guayaquil, Puntarenas, Corinto, Puerto Quetzal, Puerto Vallarta
2019 Sails: Sep 30, More...
HAL Amsterdam Cruise Ship14 Night Incan Empires
Starting in San Diego with stops in Cabo San Lucas, Huatulco, Fuerte Amador, Manta, Salaverry, Callao
2019 Sails: Sep 30, More...
HAL Volendam Cruise Ship17 Night Panama Canal
Starting in San Diego with stops in Cabo San Lucas, Puerto Chiapas, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Willemstad, Half Moon Cay, Fort Lauderdale
2019 Sails: Oct 1, More...
HAL Nieuw Amsterdam Cruise Ship16 Night Panama Canal
Starting in San Diego with stops in Puerto Vallarta, Huatulco, Puerto Chiapas, Puerto Quetzal, Corinto, Puerto Caldera, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Fort Lauderdale
2019 Sails: Oct 3, More...
Disney Wonder Cruise Ship5-Night Halloween on the High Seas Baja Cruise from San Diego
Starting in San Diego, California; with stops in Cabo San Lucas, Mexico; Ensenada, Mexico; San Diego, California
2019 Sails: Oct 4, Oct 9, More...
Star Legend Cruises2019 - San Diego to Puerto Vallarta - 7 Nights - Star Legend
Starting in San Diego with stops in Cabo San Lucas, La Paz, Loreto, Puerto Vallarta
2019 Sails: Oct 4, More...
Star Legend Cruises2019 - San Diego to Puerto Caldera - 15 Nights - Star Legend
Starting in San Diego with stops in Cabo San Lucas, La Paz, Loreto, Puerto Vallarta, Manzanillo, Huatulco, Puerto Chiapas, Playas del Coco, Bahia Herradura, Puerto Caldera
2019 Sails: Oct 4, More...
HAL Oosterdam Cruise Ship7 Night Mexican Riviera
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta
2019 Sails: Oct 6, Oct 13, Nov 23, Nov 30, Dec 7, Dec 14, 2020: Jan 4, Jan 11, Feb 22, Feb 29, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, Apr 11, Apr 18, More...
HAL Oosterdam Cruise Ship24 Night Mexican Riviera & Circle Hawaii Collector
Starting in San Diego with stops in Cabo San Lucas, Mazatlan, Puerto Vallarta, Honolulu, Lahaina, Kona, Scenic cruising Kilauea Volcano, Hilo, Ensenada
2019 Sails: Oct 13, More...


San Diego Cruise Departures

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