San Diego Cruise Departures
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
10 Night - Mexican Riviera & Sea of Cortez
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2025 Sails: Nov 29, More...
7 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2025 Sails: Nov 29, Dec 6, Dec 13, Dec 20, Dec 27, 2026: Jan 10, Jan 24, Jan 31, More...
12 Night - Historical Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...29 Night - Historical Baja Peninsula & Circle Hawaii Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...11 Night - Mexican Riviera & Sea of Cortez
Starting in San Diego, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Loreto, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 9, More...17 Night - Circle Hawaii Holiday
Starting in San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 18, More...7 Night - Baja Peninsula
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2025 Sails: Dec 20, 2026: Mar 28, More...14 Night - Mexican Riviera & Baja Peninsula Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 20, More...7 Night - Mexican Riviera Holiday
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 27, More...7 Night - Mexican Riviera
Starting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 3, More...
Cruises that depart from North America: United States: California: San Diego
Cruises that visit San Diego
Click on a cruise ship itinerary sailing from San Diego (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Diego), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Mexican Riviera & Sea of CortezStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, San Diego, California
2025 Sails: Nov 29, More...
7 Night - Mexican Riviera - San DiegoStarting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2025 Sails: Nov 29, Dec 6, Dec 13, Dec 20, Dec 27, 2026: Jan 10, Jan 24, Jan 31, More...
12 Night - Historical Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...
29 Night - Historical Baja Peninsula & Circle Hawaii HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Guaymas, Mexico, Topolobampo, Mexico, Loreto, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Ensenada, Mexico, San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 6, More...
11 Night - Mexican Riviera & Sea of CortezStarting in San Diego, California, Puerto Vallarta, Mexico, Manzanillo, Mexico, Mazatlan, Mexico, Loreto, Mexico, Pichilingue (La Paz), Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 9, More...
17 Night - Circle Hawaii HolidayStarting in San Diego, California, Hilo, Hawaii, Kahului, Maui, Kona, Hawaii, Honolulu, Hawaii, Ensenada, Mexico, San Diego, California
2025 Sails: Dec 18, More...
7 Night - Baja PeninsulaStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California
2025 Sails: Dec 20, 2026: Mar 28, More...
14 Night - Mexican Riviera & Baja Peninsula HolidayStarting in San Diego, California, Cabo San Lucas, Mexico, Pichilingue (La Paz), Mexico, Loreto, Mexico, San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 20, More...
7 Night - Mexican Riviera HolidayStarting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2025 Sails: Dec 27, More...
7 Night - Mexican RivieraStarting in San Diego, California, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, California
2026 Sails: Jan 3, More...
