Portland ME Cruise Departures
Cruises that depart from North America: United States: Maine: Portland ME
Cruises that visit Portland ME
See all River Cruises that depart from Portland ME
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...
11 Night - Contrasts of Canada & the St. Lawrence River
Starting in Portland ME, Rockland Harbour, Rockland, Maine, Campobello Island, New Brunswick, Canada, Halifax, Nova Scotia, Canada, Louisbourg, Nova Scotia, Canada, Cap-aux-Meules, Quebec, Canada, Charlottetown, Prince Edward Island, Canada, Perce, Quebec, Canada, Cruising St Lawrence River, Quebec City, Quebec, Canada, Montreal, Quebec, Canada
2026 Sails: Sep 13, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 2, 2028: Oct 6, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2027 Sails: May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, 2028: May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Sep 18, 2028: Sep 11, More...14 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 4, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2028 Sails: Sep 18, More...
Cruises that depart from North America: United States: Maine: Portland ME
Cruises that visit Portland ME
See all River Cruises that depart from Portland ME
Click on a cruise ship itinerary sailing from Portland ME (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland ME), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, More...
11 Night - Contrasts of Canada & the St. Lawrence RiverStarting in Portland ME, Rockland Harbour, Rockland, Maine, Campobello Island, New Brunswick, Canada, Halifax, Nova Scotia, Canada, Louisbourg, Nova Scotia, Canada, Cap-aux-Meules, Quebec, Canada, Charlottetown, Prince Edward Island, Canada, Perce, Quebec, Canada, Cruising St Lawrence River, Quebec City, Quebec, Canada, Montreal, Quebec, Canada
2026 Sails: Sep 13, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 2, 2028: Oct 6, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2027 Sails: May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, 2028: May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Sep 18, 2028: Sep 11, More...
14 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 4, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2028 Sails: Sep 18, More...
