Portland ME Cruise Departures
Cruises that depart from North America: United States: Maine: Portland ME
Cruises that visit Portland ME
See all River Cruises that depart from Portland ME
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, Sep 14, 2027: Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, 2028: Jul 28, Aug 11, Aug 25, Sep 8, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, More...
11 Night - Contrasts of Canada & the St. Lawrence River
Starting in Portland ME, Rockland Harbour, Rockland, Maine, Eastport, Maine, (Campobello Island), Halifax, Nova Scotia, Canada, Louisbourg, Nova Scotia, Canada, Cap-aux-Meules, Quebec, Canada, Charlottetown, Prince Edward Island, Canada, Perce, Quebec, Canada, Cruising St Lawrence River, Quebec City, Quebec, Canada, Montreal, Quebec, Canada
2026 Sails: Sep 13, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 2, More...
8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2027 Sails: May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, 2028: May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Sep 17, 2028: Sep 10, More...15 Night - New England Fall Foliage Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 4, 2028: Sep 17, More...
Cruises that depart from North America: United States: Maine: Portland ME
Cruises that visit Portland ME
See all River Cruises that depart from Portland ME
Click on a cruise ship itinerary sailing from Portland ME (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Portland ME), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, Sep 14, 2027: Jun 7, Jun 21, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, 2028: Jul 28, Aug 11, Aug 25, Sep 8, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jun 17, Jul 1, Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 17, Jul 31, Aug 14, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, More...
11 Night - Contrasts of Canada & the St. Lawrence RiverStarting in Portland ME, Rockland Harbour, Rockland, Maine, Eastport, Maine, (Campobello Island), Halifax, Nova Scotia, Canada, Louisbourg, Nova Scotia, Canada, Cap-aux-Meules, Quebec, Canada, Charlottetown, Prince Edward Island, Canada, Perce, Quebec, Canada, Cruising St Lawrence River, Quebec City, Quebec, Canada, Montreal, Quebec, Canada
2026 Sails: Sep 13, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Sep 18, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2026 Sails: Oct 2, More...
8 Night - Maine Coast & Harbors CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2027 Sails: May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, 2028: May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Sep 17, 2028: Sep 10, More...
15 Night - New England Fall Foliage CruiseStarting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Portsmouth NH, Gloucester, MA, Boston, Ma, Marthas Vineyard, MA, Nantucket Island, MA, Newport, Ri, Sag Harbor, NY, New London / Mystic, CT, Sleepy Hollow, NY, New York, NY
2027 Sails: Oct 4, 2028: Sep 17, More...
