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Charleston Cruise Departures

Cruises that depart from North America: United States: South Carolina: Charleston

Cruises that visit Charleston

Click on a cruise ship itinerary sailing from Charleston (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Charleston), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Independence Cruises7 Night - Historic South and Golden Isles Cruise from Charleston, SC to Jacksonville, FL
Starting in Charleston, SC; with stops in Beaufort, SC; Hilton Head Island, SC; Savannah, GA; Cruising the Intercoastal Waterway; Jekyll Island, GA; St. Simons Island, GA; Amelia Island, FL; Jacksonville, FL
2021 Sails: Mar 20, Apr 3, Apr 17, Nov 27, Dec 11, Dec 28, 2022: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, 2023: Feb 18, Mar 4, Mar 18, Apr 1, Apr 15, More...
American Star Cruises7 Night - Historic South and Golden Isles Cruise from Charleston, SC to Jacksonville, FL
Starting in Charleston, SC; with stops in Beaufort, SC; Hilton Head Island, SC; Savannah, GA; Cruising the Intercoastal Waterway; Jekyll Island, GA; St. Simons Island, GA; Amelia Island, FL; Jacksonville, FL
2021 Sails: Apr 10, Apr 24, 2022: Mar 26, Apr 9, Apr 23, 2023: Mar 25, Apr 8, Apr 22, More...
Independence Cruises7 Night - Mid-Atlantic Inland Passage Cruise from Charleston, SC to Baltimore, MD
Starting in Charleston, SC; with stops in Wilmington, NC; Beaufort, NC / Morehead City, NC; Kitty Hawk, NC; Norfolk, VA; St. Michaels, MD; Baltimore, MD
2021 Sails: May 1, More...
American Star Cruises7 Night - Mid-Atlantic Inland Passage Cruise from Charleston, SC to Baltimore, MD
Starting in Charleston, SC; with stops in Wilmington, NC; Beaufort, NC / Morehead City, NC; Kitty Hawk, NC; Norfolk, VA; St. Michaels, MD; Baltimore, MD
2021 Sails: May 8, More...
Carnival Sunshine Cruises4 Night - The Bahamas From Charleston, SC
Starting in Charleston with stops in Half Moon Cay
2021 Sails: Jun 3, Jul 1, Jul 29, Aug 26, Sep 23, 2022: Jan 27, Feb 24, May 19, Jun 16, Jul 14, Aug 11, Sep 8, Oct 6, Nov 3, Dec 1, Dec 30, 2023: Jan 3, Jan 26, Feb 23, Mar 23, Apr 20, More...
Carnival Sunshine Cruises5 Night - The Bahamas From Charleston, SC
Starting in Charleston with stops in Nassau, Princess Cays
2021 Sails: Jun 7, Jun 21, Jul 10, Aug 2, Aug 7, Sep 13, Nov 22, 2022: Jan 31, Feb 14, Mar 14, Mar 19, Mar 28, Apr 2, Apr 30, 2023: Apr 1, More...
Carnival Sunshine Cruises5 Night - The Bahamas From Charleston, SC
Starting in Charleston with stops in Half Moon Cay, Nassau
2021 Sails: Jun 12, Jun 26, Jul 24, Aug 21, Sep 4, Sep 18, Oct 2, Nov 27, 2022: Jan 8, Feb 5, Feb 19, Apr 16, May 14, May 28, Jun 11, Jun 25, Jul 23, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, More...
Carnival Sunshine Cruises4 Night - The Bahamas From Charleston, SC
Starting in Charleston with stops in Nassau
2021 Sails: Jun 17, Jul 15, Aug 12, Sep 9, Oct 7, Nov 18, Dec 2, Dec 16, Dec 26, Dec 30, 2022: Jan 13, Feb 10, Mar 24, Apr 7, Apr 21, May 5, Jun 2, Jun 30, Jul 28, Aug 25, Sep 22, Oct 20, Nov 17, Nov 27, More...
Carnival Sunshine Cruises5 Night - The Bahamas From Charleston, SC
Starting in Charleston with stops in Nassau, Half Moon Cay
2021 Sails: Jul 5, Jul 19, Aug 16, Aug 30, Sep 27, 2022: Jan 3, Apr 11, Apr 25, May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 9, Jul 18, Aug 1, Aug 6, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, More...
Carnival Sunshine Cruises10 Night - Southern Caribbean from Charleston, SC
Starting in Charleston with stops in Aruba, Bonaire, Grand Turk, Princess Cays
2021 Sails: Dec 6, 2022: Dec 5, More...


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