Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
Louisville River Cruise Departures

River Cruises that depart from North America: United States: Kentucky: Louisville

River Cruises that visit Louisville

See all Cruises that depart from Louisville

Ohio River Cruises

Click on a cruise ship itinerary sailing from Louisville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisville), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name


American Cruise Lines, American Heritage
American Heritage Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, 2027: Jul 9, Jul 23, Aug 6, Aug 20, 2028: Jul 8, Jul 22, Aug 5, Aug 19, More...
American Cruise Lines, American Melody
American Melody Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2026 Sails: Jul 10, Jul 24, 2027: Jul 9, Jul 23, Aug 6, 2028: Jul 22, Aug 5, More...
American Cruise Lines, American Symphony
American Symphony Cruises8 Night - Ohio River Cruise
Starting in Louisville, KY, Day of Cruising, Madison, IN, Cincinnati, OH, Day of Cruising, Marietta, OH, Day of Cruising, Pittsburgh, PA
2027 Sails: Jul 16, 2028: Jul 15, More...

Louisville River Cruise Departures