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Louisville River Cruise Departures

River Cruises that depart from North America: United States: Kentucky: Louisville

River Cruises that visit Louisville

Ohio River Cruises

Click on a river cruise ship itinerary sailing from Louisville (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just Louisville), please visit: Cruise Search or try our Virtual Cruise Advisor™.

American Duchess Cruises8 Night - Racing on the River from Louisville to Pittsburgh
Starting in Louisville; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Pittsburgh, PA
2020 Sails: Aug 30, More...
American Duchess Cruises8 Night - American Music Cruise from Louisville to Clarksville
Starting in Louisville; with stops in Bradenburg; Owensboro; Henderson; Paducah; Dover; Clarksville
2020 Sails: Sep 13, More...
Louisville River Cruise Departures
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