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Louisville River Cruise Departures

River Cruises that depart from North America: United States: Kentucky: Louisville

River Cruises that visit Louisville

Ohio River Cruises

Click on a river cruise ship itinerary sailing from Louisville (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just Louisville), please visit: Cruise Search or try our Virtual Cruise Advisor™.



American Duchess Cruises8 Night Ohio and Tennessee River Lewis and Clark Cruise from Louisville to St. Louis
Starting in Louisville; with stops in Brandenburg, KY; Owensboro, KY; Paducah, KY; Cape Girardeau, MO; Chester, IL; St. Louis, MO
2019 Sails: Jul 28, More...
American Duchess Cruises8 Night American Music Cruise from Louisville to Clarksville
Starting in Louisville; with stops in Bradenburg; Owensboro; Henderson; Paducah; Dover; Clarksville
2020 Sails: May 3, Sep 13, More...
American Countess Cruises7 Night Maiden Voyage to Pittsburgh from Louisville to Pittsburgh
Starting in Louisville, KY; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Wheeling, WV; Pittsburgh, PA
2020 Sails: Jun 7, More...
American Countess Cruises7 Night Ohio River Sojourn from Louisville to Pittsburgh
Starting in Louisville, KY; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Wheeling, WV; Pittsburgh, PA
2020 Sails: Jun 21, More...
American Countess Cruises7 Night Bourbon Cruise from Louisville to Memphis
Starting in Louisville, KY; with stops in Madison, IN; Bradenburg, KY; Owensboro, KY; Henderson, KY; Paducah, KY; New Madrid, MO; Memphis, TN
2020 Sails: Jul 5, More...
American Duchess Cruises8 Night Racing on the River from Louisville to Pittsburgh
Starting in Louisville; with stops in Madison, IN; Cincinnati, OH; Maysville, KY; Point Pleasant, WV; Marietta, OH; Pittsburgh, PA
2020 Sails: Aug 30, More...
Louisville River Cruise Departures
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