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Jacksonville Cruise Departures

Cruises that depart from North America: United States: Florida: Jacksonville

Cruises that visit Jacksonville

See all River Cruises that depart from Jacksonville

Click on a cruise ship itinerary sailing from Jacksonville (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Jacksonville), please visit: Cruise Search or try our Virtual Cruise Advisor™.


American Star Cruises7 Night - Great Rivers of Florida Cruise Roundtrip from Jacksonville, FL
Starting in Jacksonville, FL; with stops in Palatka, FL; Cruising the St. Johns to Lake George (Ocala National Forest); Green Cove Springs, FL; Cruising the Tolomato River; St. Augustine, FL; Amelia Island, FL; Jacksonville, FL
2021 Sails: Nov 21, Nov 28, Dec 5, Dec 12, 2022: Feb 19, Feb 26, Mar 5, Mar 12, Nov 20, Nov 27, Dec 4, Dec 11, 2023: Feb 18, Feb 25, Mar 4, Mar 11, Nov 19, More...
Carnival Ecstasy Cruise Ship4 Night - The Bahamas From Jacksonville, FL
Starting in Jacksonville with stops in Freeport, Nassau
2022 Sails: Jan 2, Jan 6, Jan 20, Feb 3, Feb 17, Mar 3, Mar 17, Mar 31, Apr 14, Apr 28, Nov 10, Nov 19, Dec 8, Dec 17, 2023: Jan 5, Jan 19, Feb 2, Feb 16, Mar 2, Mar 16, Mar 30, Apr 13, Apr 27, Nov 9, More...
Carnival Ecstasy Cruise Ship5 Night - The Bahamas From Jacksonville, FL
Starting in Jacksonville with stops in Nassau, Princess Cays
2022 Sails: Jan 10, Jan 15, Jan 24, Jan 29, Feb 7, Feb 12, Feb 21, Mar 12, Mar 21, Mar 26, Apr 4, Apr 9, Apr 18, Apr 23, May 2, May 7, May 16, May 21, May 30, Jun 4, Jun 13, Jun 18, Jun 27, Jul 2, More...
Victory I and II Cruises11 Night - Southern Coastal Charm Cruise Roundtrip from Amelia Island (Fernandina Beach), FL
Starting in Jacksonville, FL; with stops in Amelia Island (Fernandina Beach), FL; Brunswick, GA; Savannah, GA; Charleston, SC; Beaufort (Port Royal), SC; Jacksonville (St. Augustine), FL; Scenic Sailing on the Atlantic Ocean; West Palm Beach, FL; Freeport, Bahamas; Scenic Sailing on the Atlantic Ocean; Amelia Island (Fernandina Beach), FL
2022 Sails: Feb 10, Feb 20, Mar 2, Mar 12, Mar 22, Apr 1, Nov 13, Nov 23, Dec 3, Dec 13, Dec 23, 2023: Jan 2, Feb 16, Feb 26, Mar 8, Mar 18, Mar 28, Apr 7, Nov 19, Nov 29, Dec 9, Dec 19, Dec 29, More...
Carnival Ecstasy Cruise Ship5 Night - The Bahamas From Jacksonville, FL
Starting in Jacksonville with stops in Princess Cays, Nassau
2022 Sails: Feb 26, 2023: Dec 21, More...
Carnival Ecstasy Cruise Ship5 Night - The Bahamas From Jacksonville, FL
Starting in Jacksonville with stops in Nassau, Fun Ship Meetup, Princess Cays
2022 Sails: Mar 7, More...
National Geographic Sea Lion cruise ship7 Night - Exploring the Low Country: Cumberland Island to Charleston from Jacksonville to Charleston
Starting in Jacksonville, Florida; with stops in Fernandina Beach/EMBARK; Cumberland Island, Georgia; Jekyll Island; Brunswick; Sapelo Island; Ossabaw Island; Savannah; Daufuskie Island, South Carolina; Turtle Island; Charleston/DISEMBARK
2022 Sails: Apr 9, Apr 16, Apr 23, More...
Independence Cruises14 Night - East Coast Inland Passage Cruise from Jacksonville, FL to Baltimore, MD
Starting in Jacksonville, FL / Amelia Island, FL; with stops in Fernandina Beach, FL; Jekyll Island, GA; St. Simons Island, GA; Savannah, GA; Hilton Head, SC; Beaufort, SC; Charleston, SC; Wilmington, NC; Beaufort, NC / Morehead City, NC; Kitty Hawk, NC; Norfolk, VA; St. Michaels, MD; Baltimore, MD
2022 Sails: Apr 23, 2023: Apr 22, More...
American Star Cruises14 Night - East Coast Inland Passage Cruise from Jacksonville, FL to Baltimore, MD
Starting in Jacksonville, FL / Amelia Island, FL; with stops in Fernandina Beach, FL; Jekyll Island, GA; St. Simons Island, GA; Savannah, GA; Hilton Head, SC; Beaufort, SC; Charleston, SC; Wilmington, NC; Beaufort, NC / Morehead City, NC; Kitty Hawk, NC; Norfolk, VA; St. Michaels, MD; Baltimore, MD
2022 Sails: Apr 30, 2023: Apr 29, More...
Carnival Ecstasy Cruise Ship4 Night - 4 The Bahamas From Jacksonville, FL
Starting in Jacksonville with stops in Freeport, Nassau
2022 Sails: May 12, May 26, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, 2023: May 11, May 25, Jun 8, Jun 22, Jul 6, Jul 20, Aug 3, Aug 17, Aug 31, Sep 14, Sep 28, More...


Jacksonville Cruise Departures

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