Louisiana Cruise Departures
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Related areas: New Orleans
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 14, Jul 7, Aug 18, Sep 1, 2027: Apr 13, Oct 1, Nov 26, 2028: Oct 31, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, May 12, May 26, Sep 8, More...
7 Night - Western Caribbean
Starting in New Orleans, La, Mahogany Bay, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Apr 19, More...
7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 19, May 3, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, More...7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 26, More...
5 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: May 2, May 11, May 16, May 25, May 30, Jun 8, Jun 13, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, Aug 31, Sep 5, Sep 14, Sep 19, Sep 28, Oct 3, Oct 12, More...
7 Night - Mississippi Delta Explorer
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: May 2, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Oct 12, Oct 26, Nov 23, Dec 7, 2028: Jan 25, Feb 8, Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, More...
Cruises that depart from North America: United States: Louisiana
Cruises that visit Louisiana
See all River Cruises that depart from Louisiana
Click on a cruise ship itinerary sailing from Louisiana (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Louisiana), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: New Orleans
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 14, Jul 7, Aug 18, Sep 1, 2027: Apr 13, Oct 1, Nov 26, 2028: Oct 31, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 16, Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, May 12, May 26, Sep 8, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Mahogany Bay, Roatan, Belize, Cozumel, Mexico, New Orleans, La
2026 Sails: Apr 19, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 19, May 3, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Apr 24, May 8, Oct 30, Nov 13, Nov 27, Dec 22, 2027: Jan 5, Mar 26, Apr 9, Apr 23, May 7, May 21, Oct 29, Nov 12, Nov 26, Dec 22, 2028: Jan 5, Feb 29, Apr 7, Apr 21, May 5, May 19, Oct 14, Oct 27, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Apr 26, More...
5 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: May 2, May 11, May 16, May 25, May 30, Jun 8, Jun 13, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, Aug 31, Sep 5, Sep 14, Sep 19, Sep 28, Oct 3, Oct 12, More...
7 Night - Mississippi Delta ExplorerStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee
2026 Sails: May 2, Dec 1, 2027: Feb 9, Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Oct 12, Oct 26, Nov 23, Dec 7, 2028: Jan 25, Feb 8, Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, More...
