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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Carnival Cruise Lines, Carnival Pride
Carnival Pride10 Night - Journeys - Eastern Caribbean
Starting in Baltimore, MD, St Thomas, US Virgin Islands, San Juan, Puerto Rico, Amber Cove, Dominican Republic, Grand Turk, Baltimore, MD
2026 Sails: Apr 9, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit4 Night - Key West & Bahamas Cruise
Starting in Fort Lauderdale, Florida, Key West, Florida, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: Apr 9, More...
Explora Journeys, EXPLORA II
EXPLORA II25 Night - A Grand Journey Across the Ocean from Azure Dreams to the Legendary Shores
Starting in Miami, Kings Wharf, Horta, Ponta Delgada (Sao Miguel), Cadiz, Malaga, Spain, Barcelona, Monte Carlo, Portofino, Civitavecchia (Rome), Sorrento, Monemvasia, Milos, Piraeus (Athens)
2026 Sails: Apr 9, More...
Explora Journeys, EXPLORA II
EXPLORA II16 Night - A Grand Journey from Miami to Barcelona
Starting in Miami, Kings Wharf, Horta, Ponta Delgada (Sao Miguel), Cadiz, Malaga, Spain, Barcelona
2026 Sails: Apr 9, More...
EXPLORA II13 Night - A Journey of Azure Islands & Volcanic Wonders
Starting in Miami, Kings Wharf, Horta, Ponta Delgada (Sao Miguel), Cadiz
2026 Sails: Apr 9, More...
MSC Cruises, MSC Divina
MSC Divina13 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain
2026 Sails: Apr 9, More...
MSC Cruises, MSC Divina
MSC Divina15 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain, Cannes (Cote D Azur), France, Civitavecchia (Rome), Italy
2026 Sails: Apr 9, More...
MSC Cruises, MSC Divina
MSC Divina14 Night - Msc Grand Voyages
Starting in Miami, Florida, Road Town (Tortola), British Virgin Islands, Santa Cruz de Tenerife, Barcelona, Spain, Cannes (Cote D Azur), France
2026 Sails: Apr 9, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem15 Night - Repo - Transatlantic
Starting in New York City, Ny, Funchal, Portugal, Gibraltar, Cadiz / Seville, Spain, Motril, Spain, Ibiza, Spain, Palma Majorca, Spain, Provence, Marseille, France, Barcelona, Spain
2026 Sails: Apr 9, More...
Norwegian Cruise Line, Norwegian Star
Norwegian Star4 Night - Western Caribbean - Tampa
Starting in Tampa, Fl, Cozumel, Mexico, Tampa, Fl
2026 Sails: Apr 9, More...

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United States Cruise Departures