United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Cruises, Royal Princess

5 Night - West Coast Getaway with San Francisco
Starting in Los Angeles, California, San Francisco, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Jan 19, More...

Princess Cruises, Sky Princess

14 Night - Eastern Caribbean Adventurer
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Port Canaveral (Orlando), Florida, Amber Cove, Dominican Republic, St Maarten, San Juan, Puerto Rico, Grand Turk, Turks and Caicos, Port Canaveral (Orlando), Florida
2026 Sails: Jan 19, More...

Royal Caribbean International, Explorer of the Seas

5 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 19, More...

Royal Caribbean International, Freedom of the Seas

5 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Miami, Florida
2026 Sails: Jan 19, Feb 2, Feb 16, Mar 2, Mar 16, More...

Royal Caribbean International, Mariner of the Seas

5 Night - Western Caribbean Cruise
Starting in Galveston, Texas, Puerto Costa Maya, Mexico, Cozumel, Mexico, Galveston, Texas
2026 Sails: Jan 19, Jan 24, Feb 2, Mar 21, More...

Royal Caribbean International, Utopia of the Seas

4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 19, Jan 26, Feb 2, Feb 9, Feb 16, Feb 23, Mar 2, Mar 9, Mar 16, Mar 23, Apr 6, Apr 13, More...

American Cruise Lines, American Legend

8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, Mar 10, Mar 17, More...

Cunard Line, Queen Elizabeth

Deal link -> Special

9 Night - Western Caribbean
Starting in Miami, FL, Amber Cove, Dominican Republic, Montego Bay, Jamaica, Belize City, Belize, Cozumel, Mexico, Miami, FL
2026 Sails: Jan 20, More...

Cunard Line, Queen Elizabeth

21 Night - Caribbean Roundtrip from Miami
Starting in Miami, FL, Amber Cove, Dominican Republic, Montego Bay, Jamaica, Belize City, Belize, Cozumel, Mexico, Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Jan 20, More...

Margaritaville at Sea, Margaritaville Paradise

3 Night - Nassau Escape
Starting in Port of Palm Beach, Nassau, Bahamas, Port of Palm Beach
2026 Sails: Jan 20, Jan 27, Jan 30, Feb 6, Feb 13, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, May 15, May 22, May 29, Jun 5, Jun 12, Jun 19, Jun 26, Jul 3, Jul 10, Jul 17, More...

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United States Cruise Departures