Pittsburgh River Cruise Departures

River Cruises that depart from North America: United States: Pennsylvania: Pittsburgh

River Cruises that visit Pittsburgh

Ohio River Cruises

Click on a river cruise ship itinerary sailing from Pittsburgh (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just Pittsburgh), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

American Queen Steamboat Company, American Duchess

8 Night - Ohio River and Tennessee River Cruise from Pittsburgh to Louisville
Starting in Pittsburgh, PA; with stops in Wheeling, WV; Marietta, OH; Huntington, WV; Augusta, KY; Cincinnati, OH; Madison, IN; Louisville, KY
2021 Sails: Jun 13, More...

American Queen Steamboat Company, American Queen

American Cruise Lines, Queen of the Mississippi

10 Night - Ohio River Cruise from Pittsburgh, PA to St. Louis
Starting in Pittsburgh, PA; with stops in Marietta, OH; Maysville, KY; Cincinnati, OH; Louisville, KY; Henderson, KY; Paducah, KY; Cape Girardeau, MO; St. Louis, MO
2021 Sails: Aug 20, Sep 9, Sep 29, More...

Pittsburgh River Cruise Departures