United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Royal Caribbean International, Enchantment of the Seas

4 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Tampa, Florida
2026 Sails: Jan 22, Feb 5, Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, More...

Celebrity Cruises, Celebrity Ascent

10 Night - Ultimate Southern Caribbean
Starting in Fort Lauderdale, Florida, St Johns AG, Antigua, Roseau, Dominica, Bridgetown, Barbados, Castries, St Lucia, Basseterre, St Kitts and Nevis, Fort Lauderdale, Florida
2026 Sails: Jan 23, More...

Disney Cruise Line, Disney Dream

3 Night - Bahamian Cruise from Fort Lauderdale
Starting in Port Everglades, Disney Lookout Cay, Nassau, Port Everglades
2026 Sails: Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, Apr 3, Apr 10, Apr 17, Apr 24, More...

Disney Cruise Line, Disney Fantasy

5 Night - Bahamian Cruise from Port Canaveral with Pixar Day at Sea
Starting in Port Canaveral, Disney Lookout Cay, Castaway Cay, Port Canaveral
2026 Sails: Jan 23, Feb 6, Feb 20, Mar 6, More...

Disney Cruise Line, Disney Wish

3 Night - Bahamian Cruise from Port Canaveral
Starting in Port Canaveral, Nassau, Castaway Cay, Port Canaveral
2026 Sails: Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, Oct 2, Oct 9, Oct 16, Oct 23, Oct 30, Nov 6, Nov 13, Nov 20, Nov 27, Dec 4, Dec 11, Dec 18, Dec 28, 2027: Jan 8, More...

Margaritaville at Sea, Margaritaville Islander

7 Night - Jamaica & Western Caribbean
Starting in Port Tampa Bay, Cozumel, Mexico, Montego Bay, Jamaica, George Town, Grand Cayman, Port Tampa Bay
2026 Sails: Jan 23, Aug 15, Aug 29, More...

Margaritaville at Sea, Margaritaville Paradise

4 Night - Bahamas Duo
Starting in Port of Palm Beach, Nassau, Bahamas, Freeport, Grand Bahama, Port of Palm Beach
2026 Sails: Jan 23, Mar 30, Apr 6, Apr 13, May 25, Jun 22, Jun 29, Jul 6, Jul 20, Aug 10, Aug 17, Sep 7, Nov 30, Dec 24, Dec 28, More...

Norwegian Cruise Line, Norwegian Breakaway

11 Night - Southern Caribbean - New York
Starting in New York City, Ny, Puerto Plata, Dominican Republic, San Juan, Pr, Tortola, British Virgin Islands, Philipsburg, St Maarten, Netherland Antilles, St Thomas, Vi, New York City, Ny
2026 Sails: Jan 23, Feb 3, More...

Royal Caribbean International, Adventure of the Seas

Deal link -> Special

8 Night - Eastern Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Charlotte Amalie, St Thomas, St Croix, US Virgin Islands, Orlando (Port Canaveral), Fl
2026 Sails: Jan 23, Feb 6, Mar 6, Apr 3, Apr 17, More...

Royal Caribbean International, Navigator of the Seas

3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Jan 23, Feb 27, Mar 6, Mar 27, More...

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United States Cruise Departures