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San Francisco Cruise Departures

Cruises that depart from North America: United States: California: San Francisco

Cruises that visit San Francisco

Click on a cruise ship itinerary sailing from San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.




Coral Princess Cruise Ship15 Nights - Panama Canal - Ocean to Ocean - San Francisco to Fort Lauderdale aboard Coral Princess
Starting in San Francisco with stops in Cabo San Lucas, San Juan del Sur, Puntarenas, Fuerte Amador, Panama Canal - Full Transit, Cartagena, Fort Lauderdale
2019 Sails: Nov 17, More...
Grand Princess Cruise Ship15 Nights - Hawaiian Islands - San Francisco to San Francisco aboard Grand Princess
Starting in San Francisco with stops in Hilo, Honolulu, Nawiliwili, Lahaina, Ensenada
2019 Sails: Nov 18, More...
Grand Princess Cruise Ship10 Nights - Mexican Riviera - San Francisco to San Francisco aboard Grand Princess
Starting in San Francisco with stops in Cabo San Lucas, Mazatlan, Manzanillo, Puerto Vallarta
2019 Sails: Dec 18, More...
Grand Princess Cruise Ship15 Nights - Hawaiian Islands - San Francisco to San Francisco aboard Grand Princess
Starting in San Francisco with stops in Hilo, Honolulu, Nawiliwili, Lahaina, Ensenada
2019 Sails: Dec 28, More...
Grand Princess Cruise Ship10 Nights - Mexican Riviera - San Francisco to San Francisco aboard Grand Princess
Starting in San Francisco with stops in Puerto Vallarta, Manzanillo, Mazatlan, Cabo San Lucas
2020 Sails: Jan 12, More...
NCL Norwegian Gem Cruise Ship21 Night Panama Canal from San Francisco
Starting in San Francisco with stops in Santa Barbara, Los Angeles, Cabo San Lucas, Puerto Vallarta, Zihuatanejo/Ixtapa, Puerto Quetzal, Corinto, Puntarenas, Daylight Transit Panama Canal, Cartagena, Santa Marta, Oranjestad, Willemstad, Kralendijk, New York
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship131 Night - San Francisco California to San Francisco California on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti, Bora Bora, Pago Pago, Date Line Going West, Apia, Lautoka, Auckland, Tauranga, Napier, Wellington, Cruising the Tasman Sea, Sydney, Brisbane, Cruising the Coral Sea, Airlie Beach, Cairns, Cooktown, Cruising The Torres Strait, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Cruising the Indian Ocean, Benoa, Surabaya, Cruising the Java Sea, Singapore, Port Klang, Penang, Langkawi, Phuket, Cruising the Andaman Sea, Cruising the Bay of Bengal, Colombo, Cruising the Laccadive Sea, Kochi, Mangalore, Mormugao, Bombay, Cruising the Arabian Sea, Muscat, Fujairah, Dubai, Abu Dhabi, Khasab, Salalah, Cruising the Gulf of Aden, Cruising the Red Sea, Aqaba, Safaga, Suez Canal Transit, Haifa, Cruising the Mediterranean Sea, Kusadasi, Piraeus, Cruising the Ionian Sea, Sicily, Sorrento/Capri, Civitavecchia, Livorno, Monte Carlo, Barcelona, Alicante, Malaga, Cruising the Atlantic Ocean, Azores, Hamilton, Miami, Cruising the Florida Straits, Cruising the Caribbean Sea, Cartagena, Colon, Panama Canal Daylight Transit, Puntarenas, San Juan del Sur, Puerto Quetzal, Acapulco, Mazatlan, Cabo San Lucas, San Diego
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship18 Night - San Francisco California to Papeete (Tahiti) French Polynesia on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship54 Night - San Francisco California to Singapore Singapore on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti, Bora Bora, Pago Pago, Date Line Going West, Apia, Lautoka, Auckland, Tauranga, Napier, Wellington, Cruising the Tasman Sea, Sydney, Brisbane, Cruising the Coral Sea, Airlie Beach, Cairns, Cooktown, Cruising The Torres Strait, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Cruising the Indian Ocean, Benoa, Surabaya, Cruising the Java Sea, Singapore
2020 Sails: Jan 24, More...


San Francisco Cruise Departures

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