San Francisco Cruise Departures
Cruises that depart from North America: United States: California: San Francisco
Cruises that visit San Francisco
5 Night - West Coast Getaway with San Diego
Starting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2025 Sails: Nov 26, 2026: Feb 14, More...16 Night - Hawaiian Islands
Starting in San Francisco, California, Hilo, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2025 Sails: Dec 1, 2026: Mar 18, More...
16 Night - Panama Canal - Ocean to Ocean
Starting in San Francisco, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Cartagena CO, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...16 Night - Hawaiian Islands Holiday
Starting in San Francisco, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Francisco, California
2025 Sails: Dec 17, More...16 Night - Hawaiian Islands
Starting in San Francisco, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Jan 2, More...11 Night - Mexican Riviera
Starting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Jan 18, Mar 7, More...16 Night - Hawaiian Islands
Starting in San Francisco, California, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kona, Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Jan 29, Feb 19, More...
91 Night - San Francisco to New York
Starting in San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia, Brisbane, Australia, Yorkeys Knob (tours to Cairns), Australia, Darwin, NT, Australia, Bitung, Indonesia, Hong Kong, China, Chan May (tours to Hue or Da Nang), Vietnam, Singapore, Port Kelang (tours to Kuala Lumpur), Malaysia, Port Louis, Mauritius, Durban, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK, Le Havre, France, New York, NY
2026 Sails: Feb 6, More...26 Night - San Francisco to Sydney
Starting in San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia
2026 Sails: Feb 6, More...16 Night - Hawaiian Islands
Starting in San Francisco, California, Kahului, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Hilo, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Apr 3, More...
Cruises that depart from North America: United States: California: San Francisco
Cruises that visit San Francisco
Click on a cruise ship itinerary sailing from San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.
5 Night - West Coast Getaway with San DiegoStarting in San Francisco, California, San Diego, California, Ensenada, Mexico, San Francisco, California
2025 Sails: Nov 26, 2026: Feb 14, More...
16 Night - Hawaiian IslandsStarting in San Francisco, California, Hilo, Hawaii, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2025 Sails: Dec 1, 2026: Mar 18, More...
16 Night - Panama Canal - Ocean to OceanStarting in San Francisco, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Cartagena CO, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...
16 Night - Hawaiian Islands HolidayStarting in San Francisco, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kona, Hawaii, Ensenada, Mexico, San Francisco, California
2025 Sails: Dec 17, More...
16 Night - Hawaiian IslandsStarting in San Francisco, California, Hilo, Hawaii, Honolulu, Hawaii, Kahului, Hawaii, Kauai (Nawiliwili), Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Jan 2, More...
11 Night - Mexican RivieraStarting in San Francisco, California, Manzanillo, Mexico, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Francisco, California
2026 Sails: Jan 18, Mar 7, More...
16 Night - Hawaiian IslandsStarting in San Francisco, California, Honolulu, Hawaii, Kauai (Nawiliwili), Hawaii, Kona, Hawaii, Kahului, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Jan 29, Feb 19, More...
91 Night - San Francisco to New YorkStarting in San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia, Brisbane, Australia, Yorkeys Knob (tours to Cairns), Australia, Darwin, NT, Australia, Bitung, Indonesia, Hong Kong, China, Chan May (tours to Hue or Da Nang), Vietnam, Singapore, Port Kelang (tours to Kuala Lumpur), Malaysia, Port Louis, Mauritius, Durban, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Dakar, Senegal, Tenerife, Spain, Cadiz (tours to Seville), Spain, Southampton, England, UK, Le Havre, France, New York, NY
2026 Sails: Feb 6, More...
Deal link -> Special
26 Night - San Francisco to SydneyStarting in San Francisco, CA, Honolulu, HI, Kona, HI, Papeete, French Polynesia, Moorea, French Polynesia, Cross International Date Line (Cruise-by), Bay of Islands, New Zealand, Auckland, New Zealand, Tauranga, New Zealand, Sydney AU, Australia
2026 Sails: Feb 6, More...
16 Night - Hawaiian IslandsStarting in San Francisco, California, Kahului, Hawaii, Honolulu, Hawaii, Kona, Hawaii, Hilo, Hawaii, Ensenada, Mexico, San Francisco, California
2026 Sails: Apr 3, More...
