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San Francisco Cruise Departures

Cruises that depart from North America: United States: California: San Francisco

Cruises that visit San Francisco

Click on a cruise ship itinerary sailing from San Francisco (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just San Francisco), please visit: Cruise Search or try our Virtual Cruise Advisor™.




NCL Norwegian Gem Cruise Ship21 Night - Panama Canal from San Francisco
Starting in San Francisco with stops in Santa Barbara, Los Angeles, Cabo San Lucas, Puerto Vallarta, Zihuatanejo/Ixtapa, Puerto Quetzal, Corinto, Puntarenas, Daylight Transit Panama Canal, Cartagena, Santa Marta, Oranjestad, Willemstad, Kralendijk, New York
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship131 Night - San Francisco California to San Francisco California on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti, Bora Bora, Pago Pago, Date Line Going West, Apia, Lautoka, Auckland, Tauranga, Napier, Wellington, Cruising the Tasman Sea, Sydney, Brisbane, Cruising the Coral Sea, Airlie Beach, Cairns, Cooktown, Cruising The Torres Strait, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Cruising the Indian Ocean, Benoa, Surabaya, Cruising the Java Sea, Singapore, Port Klang, Penang, Langkawi, Phuket, Cruising the Andaman Sea, Cruising the Bay of Bengal, Colombo, Cruising the Laccadive Sea, Kochi, Mangalore, Mormugao, Bombay, Cruising the Arabian Sea, Muscat, Fujairah, Dubai, Abu Dhabi, Khasab, Salalah, Cruising the Gulf of Aden, Cruising the Red Sea, Aqaba, Safaga, Suez Canal Transit, Haifa, Cruising the Mediterranean Sea, Kusadasi, Piraeus, Cruising the Ionian Sea, Sicily, Sorrento/Capri, Civitavecchia, Livorno, Monte Carlo, Barcelona, Alicante, Malaga, Cruising the Atlantic Ocean, Azores, Hamilton, Miami, Cruising the Florida Straits, Cruising the Caribbean Sea, Cartagena, Colon, Panama Canal Daylight Transit, Puntarenas, San Juan del Sur, Puerto Quetzal, Acapulco, Mazatlan, Cabo San Lucas, San Diego
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship18 Night - San Francisco California to Papeete (Tahiti) French Polynesia on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti
2020 Sails: Jan 24, More...
Seven Seas Mariner Cruise Ship54 Night - San Francisco California to Singapore Singapore on Seven Seas Mariner
Starting in San Francisco with stops in Cruising the Pacific Ocean, Honolulu, Kahului, Hilo, Nuku Hiva, Fakarava, Moorea, Tahiti, Bora Bora, Pago Pago, Date Line Going West, Apia, Lautoka, Auckland, Tauranga, Napier, Wellington, Cruising the Tasman Sea, Sydney, Brisbane, Cruising the Coral Sea, Airlie Beach, Cairns, Cooktown, Cruising The Torres Strait, Cruising the Arafura Sea, Darwin, Cruising the Timor Sea, Cruising the Indian Ocean, Benoa, Surabaya, Cruising the Java Sea, Singapore
2020 Sails: Jan 24, More...
Oceania Insignia Cruise Ship162 Night - Bridgeway to Exploration - San Francisco California to San Francisco California
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael, Cruising the Chilean Fjords, Punta Arenas, Cruising around Cape Horn, Ushuaia, Cruising the Atlantic Ocean, Port Stanley, Puerto Madryn, Buenos Aires, Montevideo, Punta del Este, Rio Grande, Porto Belo, Santos, Parati, Ilha Grande, Buzios, Rio de Janeiro, Recife, Natal, Fortaleza, Sao Vicente, Dakar, Banjul, Abidjan, Sekondi-takoradi, Lome, Walvis Bay, Cape Town, Mossel Bay, Cruising the Indian Ocean, Durban, Richards Bay, Maputo, Pointe des Galets, Port Louis, Male, Cruising the Laccadive Sea, Kochi, Colombo, Cruising the Bay of Bengal, Cruising the Andaman Sea, Yangon, Phuket, Penang, Port Klang, Singapore, Cruising the Gulf of Thailand, Ko Samui, Bangkok, Sihanoukville, Cruising the South China Sea, Ho Chi Minh City, Da Nang, Ha Long Bay, Hong Kong, Xiamen, Cruising the East China Sea, Shanghai, Cruising the Yellow Sea, Tianjin, Jeju, Busan, Nagasaki, Kagoshima, Hiroshima, Kobe, Shimizu, Tokyo, Oarai, Aomori, Hakodate, Petropavlovsk-Kamchatsky, Int'l Date Line East, Cruising The Aleutian Basin, Aleutian Islands, Kodiak, Seward, Cruising Hubbard Glacier, Juneau, Sitka, Prince Rupert, Cruising the Inside Passage, Victoria, Astoria
2020 Sails: Jan 26, More...
Oceania Insignia Cruise Ship177 Night - Continental Passage - San Francisco California to Miami Florida
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael, Cruising the Chilean Fjords, Punta Arenas, Cruising around Cape Horn, Ushuaia, Cruising the Atlantic Ocean, Port Stanley, Puerto Madryn, Buenos Aires, Montevideo, Punta del Este, Rio Grande, Porto Belo, Santos, Parati, Ilha Grande, Buzios, Rio de Janeiro, Recife, Natal, Fortaleza, Sao Vicente, Dakar, Banjul, Abidjan, Sekondi-takoradi, Lome, Walvis Bay, Cape Town, Mossel Bay, Cruising the Indian Ocean, Durban, Richards Bay, Maputo, Pointe des Galets, Port Louis, Male, Cruising the Laccadive Sea, Kochi, Colombo, Cruising the Bay of Bengal, Cruising the Andaman Sea, Yangon, Phuket, Penang, Port Klang, Singapore, Cruising the Gulf of Thailand, Ko Samui, Bangkok, Sihanoukville, Cruising the South China Sea, Ho Chi Minh City, Da Nang, Ha Long Bay, Hong Kong, Xiamen, Cruising the East China Sea, Shanghai, Cruising the Yellow Sea, Tianjin, Jeju, Busan, Nagasaki, Kagoshima, Hiroshima, Kobe, Shimizu, Tokyo, Oarai, Aomori, Hakodate, Petropavlovsk-Kamchatsky, Int'l Date Line East, Cruising The Aleutian Basin, Aleutian Islands, Kodiak, Seward, Cruising Hubbard Glacier, Juneau, Sitka, Prince Rupert, Cruising the Inside Passage, Victoria, Astoria, Corinto, Puntarenas, Panama Canal Daylight Transit, Cartagena, Cruising the Caribbean Sea, Cruising the Old Bahama Channel, Miami
2020 Sails: Jan 26, More...
Oceania Insignia Cruise Ship182 Night - Connoisseur's Collection - San Francisco California to New York New York
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael, Cruising the Chilean Fjords, Punta Arenas, Cruising around Cape Horn, Ushuaia, Cruising the Atlantic Ocean, Port Stanley, Puerto Madryn, Buenos Aires, Montevideo, Punta del Este, Rio Grande, Porto Belo, Santos, Parati, Ilha Grande, Buzios, Rio de Janeiro, Recife, Natal, Fortaleza, Sao Vicente, Dakar, Banjul, Abidjan, Sekondi-takoradi, Lome, Walvis Bay, Cape Town, Mossel Bay, Cruising the Indian Ocean, Durban, Richards Bay, Maputo, Pointe des Galets, Port Louis, Male, Cruising the Laccadive Sea, Kochi, Colombo, Cruising the Bay of Bengal, Cruising the Andaman Sea, Yangon, Phuket, Penang, Port Klang, Singapore, Cruising the Gulf of Thailand, Ko Samui, Bangkok, Sihanoukville, Cruising the South China Sea, Ho Chi Minh City, Da Nang, Ha Long Bay, Hong Kong, Xiamen, Cruising the East China Sea, Shanghai, Cruising the Yellow Sea, Tianjin, Jeju, Busan, Nagasaki, Kagoshima, Hiroshima, Kobe, Shimizu, Tokyo, Oarai, Aomori, Hakodate, Petropavlovsk-Kamchatsky, Int'l Date Line East, Cruising The Aleutian Basin, Aleutian Islands, Kodiak, Seward, Cruising Hubbard Glacier, Juneau, Sitka, Prince Rupert, Cruising the Inside Passage, Victoria, Astoria, Corinto, Puntarenas, Panama Canal Daylight Transit, Cartagena, Cruising the Caribbean Sea, Cruising the Old Bahama Channel, Miami, Port Canaveral, Charleston, New York
2020 Sails: Jan 26, More...
Oceania Insignia Cruise Ship38 Night - Pacific & Atlantic Icons - San Francisco California to Buenos Aires Argentina
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael, Cruising the Chilean Fjords, Punta Arenas, Cruising around Cape Horn, Ushuaia, Cruising the Atlantic Ocean, Port Stanley, Puerto Madryn, Buenos Aires
2020 Sails: Jan 26, More...
Oceania Insignia Cruise Ship49 Night - Allure of the Americas - San Francisco California to Rio De Janeiro Brazil
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio, Puerto Montt, Puerto Chacabuco, Laguna San Rafael, Cruising the Chilean Fjords, Punta Arenas, Cruising around Cape Horn, Ushuaia, Cruising the Atlantic Ocean, Port Stanley, Puerto Madryn, Buenos Aires, Montevideo, Punta del Este, Rio Grande, Porto Belo, Santos, Parati, Ilha Grande, Buzios, Rio de Janeiro
2020 Sails: Jan 26, More...
Oceania Insignia Cruise Ship22 Night - Pacific Coast Sojourn - San Francisco California to Santiago De Chile (San Antonio) Chile
Starting in San Francisco with stops in Santa Barbara, San Diego, Cruising the Pacific Ocean, Cabo San Lucas, IXTAPA, Acapulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Manta, Salaverry, Callao, Pisco/Nazca Lines, Coquimbo, San Antonio
2020 Sails: Jan 26, More...


San Francisco Cruise Departures

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