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California Cruise Departures

Cruises that depart from North America: United States: California

Cruises that visit California

Click on a cruise ship itinerary sailing from California (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just California), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Long Beach : Los Angeles : San Diego : San Francisco

Departing from
California
Cruise Specials

Royal Caribbean, Quantum of the Seas
Quantum of the Seas3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 21, More...
Holland America, Zuiderdam
Zuiderdam26 Night - Panama Canal & Eastern Caribbean
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Fort-De-France, Martinique, Roseau, Dominica, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
Holland America, Zuiderdam
Zuiderdam15 Night - Panama Canal
Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Feb 27, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas5 Night - Cabo Overnight Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Los Angeles, California
2026 Sails: Feb 27, Mar 13, Mar 27, More...
Princess Cruises, Royal Princess
Royal Princess7 Night - Mexican Riviera
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Feb 28, Mar 7, Mar 14, Mar 21, Apr 11, Apr 18, More...
Norwegian Cruise Line, Norwegian Bliss
Norwegian Bliss7 Night - Mexican Riviera - Los Angeles
Starting in Los Angeles, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Mar 1, More...
Disney Cruise Line, Disney Wonder
Disney Wonder4 Night - Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Mar 2, Mar 23, Mar 30, Apr 13, More...
Royal Caribbean, Navigator of the Seas
Navigator of the Seas4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Mar 2, Mar 30, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas6 Night - Cabo Overnight and Ensenada
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Mar 4, Mar 18, Apr 1, Apr 15, More...
Disney Cruise Line, Disney Wonder
Disney Wonder3 Night - Baja Cruise from San Diego
Starting in San Diego, Catalina, Ensenada, San Diego
2026 Sails: Mar 6, Mar 13, Mar 20, Apr 3, Apr 10, Apr 17, May 1, More...

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California Cruise Departures