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United States River Cruise Departures

River Cruises that depart from North America: United States

River Cruises that visit United States

See all Cruises that depart from United States

Click on a river cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Related areas: Illinois : Kentucky : Louisiana : Minnesota : Missouri : Ohio : Oregon : Pennsylvania : Tennessee : Washington




American Pride Cruises7 Night Columbia and Snake Rivers from Clarkston, WA to Portland, OR
Starting in Clarkston, Washington; with stops in Pendleton, Oregon; The Dalles, Oregon; Stevenson, Washington; Rainier, Oregon; Astoria, Oregon; Portland, Oregon
2019 Sails: Sep 21, Oct 5, Oct 19, More...
American Song Cruises10 Night Northwest Pioneers Cruise from Portland to Clarkston
Starting in Portland, OR; with stops in Astoria, OR; Mt. St. Helens, WA; Portland, OR; Stevenson, WA; Hood River, OR; The Dalles; Richland, WA; Pendleton, OR; Clarkston, WA
2019 Sails: Sep 21, Oct 11, 2020: May 21, Jul 8, Sep 5, Sep 25, More...
Queen of the Mississippi Cruises7 Night Cumberland River Cruise from St. Louis to Nashville
Starting in St. Louis, MO; with stops in Chester, IL; Cape Girardeau, MO; Paducah, KY; Dover, TN; Clarksville, TN; Nashville, TN
2019 Sails: Sep 21, 2020: Sep 5, Sep 19, More...
Queen of the West Cruises7 Nights Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Ranier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2019 Sails: Sep 22, Oct 6, 2020: Mar 13, Mar 27, Apr 10, Apr 24, May 16, May 30, Jun 13, Jul 5, Jul 19, Aug 2, Aug 16, Aug 30, Sep 13, Sep 27, More...
American Duchess Cruises8 Night Lower Mississippi River Cruise from Memphis to New Orleans
Starting in Memphis; with stops in Helena, AR; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation, LA; New Orleans, LA
2019 Sails: Sep 22, Oct 6, Oct 20, Nov 3, Nov 17, More...
American Empress Cruises8 Night The Beauty and Bounty of Nature from Clarkston to Vancouver, WA
Starting in Spokane, WA; with stops in Clarkston, WA; Richland, WA; The Dalles, OR; Stevenson, WA; Astoria, OR; Vancouver, WA
2019 Sails: Sep 22, Oct 6, Oct 20, Nov 3, More...
American Queen Cruises8 Night Lower Mississippi River Antebellum South Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation, LA; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Greenville, MS; Memphis, TN
2019 Sails: Sep 22, Oct 6, Oct 20, Nov 17, Dec 1, More...
America Cruises7 Night Upper Mississippi River from St. Paul, MN to St. Louis, MO
Starting in St. Paul, MN; with stops in Red Wing, MN; La Crosse, WI; Dubuque, IA; Davenport, IA; Hannibal, MO; St. Louis, MO
2019 Sails: Sep 24, 2020: Sep 27, More...
American Harmony Cruises7 Night New Orleans to New Orleans Cruise New Orleans, Louisiana to New Orleans, Louisiana
Starting in New Orleans, with stops in Oak Alley, Natchez, Vicksburg, St Francisville, Baton Rouge, Houmas House, New Orleans
2019 Sails: Sep 28, Nov 8, Nov 15, Nov 22, Dec 5, Dec 12, Dec 20, Dec 28, 2020: Nov 5, Dec 2, Dec 12, Dec 20, Dec 28, More...
American Pride Cruises7 Nights Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2019 Sails: Sep 28, Oct 26, More...


United States River Cruise Departures
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