CruiseCompete: Easily Compare Multiple Offers from Cruise Experts
Compare offers from multiple travel agencies
1
Find your cruise
& request quotes
2
Compare members only prices,
upgrades, cabin credits & more!
3
Contact your preferred agent
for questions or to book your cruise
Over 1 million members
United States River Cruise Departures

River Cruises that depart from North America: United States

River Cruises that visit United States

See all Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

River cruises by river name

Related areas: Florida : Georgia : Illinois : Kentucky : Louisiana : Maine : Massachusetts : Michigan : Minnesota : Missouri : Ohio : Oregon : Pennsylvania : Tennessee : Washington


America Cruises7 Night - Upper Mississippi River Cruise from St. Louis, MO to St. Paul, MN
Starting in St. Louis, MO; with stops in Hannibal, MO; Fort Madison, IA; Davenport, IA; Dubuque, IA; Winona, MN; Red Wing, MN; St. Paul, MN
2021 Sails: Aug 4, Sep 4, Sep 18, Oct 2, Oct 16, 2022: Jul 20, Aug 3, Sep 3, Sep 17, Oct 1, Oct 15, 2023: Jul 19, Aug 2, Sep 2, Sep 16, Sep 30, Oct 14, More...
American Harmony Cruises7 Night - Columbia and Snake River Cruise from Clarkston, WA to Portland, OR
Starting in Clarkston, WA; with stops in Pendleton, OR; Richland, WA; The Dalles, OR; Cruising the Columbia River Gorge; Stevenson, WA; Mount St. Helens, WA; Astoria, OR; Portland, OR
2021 Sails: Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, Nov 24, 2022: Mar 10, Mar 24, Apr 7, Apr 28, May 12, May 26, Jun 9, Jun 23, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, Oct 13, More...
American Pride Cruises7 Night - Columbia and Snake Rivers Cruise from Clarkston, WA to Portland, OR
Starting in Clarkston, WA; with stops in Pendleton, OR; Richland, WA; The Dalles, OR; Cruising the Columbia River Gorge; Stevenson, WA; Mount St. Helens, WA; Astoria, OR; Portland, OR
2021 Sails: Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, 2022: Apr 22, May 6, May 20, Jun 3, Jun 17, Jul 8, Jul 22, Aug 5, Aug 19, Sep 2, Sep 16, Oct 7, Oct 21, Nov 4, 2023: Mar 10, More...
Queen of the West Cruises7 Night - Columbia and Snake Rivers Cruise from Portland, OR to Clarkston, WA
Starting in Portland, OR; with stops in Astoria, OR; Mount St. Helens, WA; Cruising the Columbia River Gorge; Stevenson, WA; The Dalles, OR; Pendleton, OR; Richland, WA; Clarkston, WA
2021 Sails: Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, 2022: Apr 9, Apr 23, May 7, May 21, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, 2023: Apr 8, Apr 22, May 6, May 20, Jun 24, Jul 8, Jul 22, More...
American Countess Cruises8 Night - New Orleans to Memphis
Starting in New Orleans, LA; with stops in Nottoway; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2021 Sails: Aug 7, Sep 11, Oct 23, Dec 4, Dec 18, 2022: Mar 14, Mar 28, Apr 11, Oct 10, Nov 14, 2023: Mar 6, Mar 20, Apr 3, Apr 17, Sep 18, Nov 6, Nov 20, Dec 4, More...
Victory I and II Cruises10 Night - Splendor of the Great Lakes Cruise from Chicago to Toronto
Starting in Chicago, IL; with stops in Chicago, IL; Scenic Sailing on Lake Michigan; Mackinac Island, MI; Sault Ste. Marie, MI; Little Current/Manitoulin Island, ON; Scenic Sailing on Lake Huron; Detroit, MI; Cleveland, OH; Niagara Falls (Port Colborne), ON; Toronto, ON
2021 Sails: Aug 7, Aug 25, Sep 12, Sep 30, 2022: May 17, May 20, Jun 7, Jun 25, Jul 2, Jul 13, Jul 20, Jul 31, Aug 7, Aug 18, Sep 5, 2023: May 16, Jun 13, Jul 1, Jul 19, Aug 6, Aug 25, Sep 11, More...
Victory I and II Cruises12 Night - Great Lakes Grand Discovery Cruise from Chicago to Montreal
Starting in Chicago, IL; Scenic Sailing on Lake Michigan; with stops in Mackinac Island, MI; Sault Ste. Marie, MI; Little Current/Manitoulin Island, ON; Scenic Sailing on Lake Huron; Detroit, MI; Cleveland, OH; Niagara Falls (Port Colborne), ON; Toronto, ON; Scenic Sailing on Lake Ontario; Montreal, QC
2021 Sails: Aug 7, Oct 18, 2022: Aug 25, Sep 23, 2023: Aug 24, Sep 29, More...
American Jazz Cruises7 Night - Music Cities Cruise from Nashville, TN to Memphis, TN
Starting in Nashville, TN; with stops in Clarksville, TN; Dover, TN; Cruising Lake Barkley and the Cumberland River; Paducah, KY; Cruising the Mississippi and Ohio River; Memphis TN
2021 Sails: Aug 8, Aug 22, Sep 5, Sep 19, 2022: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2023: Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, More...
American Song Cruises7 Night - Columbia and Snake Rivers Cruise from Clarkston, WA to Portland, OR
Starting in Clarkston, WA; with stops in Pendleton, OR; Richland, WA; The Dalles, OR; Cruising the Columbia River Gorge; Stevenson, WA; Mount St. Helens, WA; Astoria, OR; Portland, OR
2021 Sails: Aug 8, Aug 22, Sep 5, Oct 10, Oct 24, Nov 7, 2022: Mar 20, Apr 3, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 9, Oct 23, Nov 6, Nov 20, 2023: Feb 26, More...
American Empress Cruises8 Night - Spokane, WA (Clarkston, WA) to Portland, OR (Vancouver, WA)
Starting in Spokane, WA; with stops in Clarkston, WA; Richland, WA; The Dalles, OR; Stevenson, WA; Astoria, OR; Vancouver, WA
2021 Sails: Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 17, 2022: Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, Oct 2, Oct 16, 2023: Mar 26, Apr 9, More...


United States River Cruise Departures

Connecting cruisers with the best cruise prices on discount cruises since 2003. Privacy Policy

Cruise news from Cruise Compete, where you compare cruise prices to get the best cruise discounts and deals
Let our Virtual Cruise Advisor(TM) recommend the best cruises for you.