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United States River Cruise Departures

River Cruises that depart from North America: United States

River Cruises that visit United States

See all Cruises that depart from United States

Click on a river cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all river cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Related areas: Illinois : Kentucky : Louisiana : Minnesota : Missouri : Oregon : Pennsylvania : Tennessee : Washington




American Pride Cruises7 Night - Columbia and Snake Rivers from Clarkston, WA to Portland, OR
Starting in Clarkston, Washington; with stops in Pendleton, Oregon; The Dalles, Oregon; Stevenson, Washington; Rainier, Oregon; Astoria, Oregon; Portland, Oregon
2020 Sails: Jul 25, Aug 8, Aug 22, Sep 5, Sep 19, Oct 3, Oct 31, 2021: Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, Nov 12, Nov 26, More...
American Song Cruises7 Night - Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainer, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2020 Sails: Jul 25, Aug 8, Aug 22, Oct 15, Oct 26, Nov 9, Nov 23, 2021: Mar 25, Mar 28, May 2, May 16, May 30, Jun 13, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Oct 17, Oct 31, Nov 14, More...
Queen of the West Cruises7 Night - Columbia and Snake Rivers from Clarkston, WA to Portland, OR
Starting in Clarkston, Washington; with stops in Pendleton, Oregon; The Dalles, Oregon; Stevenson, Washington; Rainier, Oregon; Astoria, Oregon; Portland, Oregon
2020 Sails: Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 26, 2021: Apr 3, Apr 17, May 15, Jul 17, Jul 31, Sep 11, More...
American Countess Cruises7 Night - Antebellum South from Memphis to New Orleans
Starting in Memphis, TN; with stops in Port of the Mississippi Delta; Vicksburg, MS; Natchez, MS; Baton Rouge, LA; St. Francisville, LA; Nottoway Plantation; New Orleans, LA
2020 Sails: Jul 26, Aug 9, Oct 11, Nov 8, Nov 22, More...
American Duchess Cruises8 Night - Heartland Heritage Cruise roundtrip from Red Wing
Starting in Red Wing; with stops in La Crosse, WI; Dubuque, IA; Prairie du Chien, WI; Winona, MN
2020 Sails: Jul 26, More...
American Empress Cruises8 Night - The Beauty and Bounty of Nature from Clarkston, WA to Vancouver WA
Starting in Clarkston, WA; with stops in Richland, WA; The Dalles, OR; Stevenson, WA; Astoria, OR; Vancouver, WA
2020 Sails: Jul 26, Aug 9, Aug 23, Sep 6, Sep 20, Oct 4, Oct 18, Nov 1, Nov 15, More...
American Queen Cruises8 Night - Mark Twain's Mississippi Cruise from Alton to Red Wing
Starting in Alton; with stops in Hannibal, MO; Clinton, IA; Dubuque, IA; La Crosse, WI; Red Wing, MN
2020 Sails: Jul 26, Aug 9, More...
American Pride Cruises7 Night - Columbia and Snake Rivers from Portland, OR to Clarkston, WA
Starting in Portland, Oregon; with stops in Astoria, Oregon; Rainier, Oregon; Stevenson, Washington; The Dalles, Oregon; Pendleton, Oregon; Richland, Washington; Clarkston, Washington
2020 Sails: Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, 2021: Apr 30, May 14, May 28, Jun 11, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, More...
American Song Cruises7 Night - Columbia and Snake Rivers from Clarkston, WA to Portland, OR
Starting in Clarkston, Washington; with stops in Pendleton, Oregon; The Dalles, Oregon; Stevenson, Washington; Rainier, Oregon; Astoria, Oregon; Portland, Oregon
2020 Sails: Aug 1, Aug 15, Aug 21, Aug 29, Oct 5, Oct 19, Nov 2, Nov 16, Nov 30, 2021: Mar 21, Apr 4, Apr 25, May 9, May 31, Jun 6, Jun 20, Jul 11, Jul 25, Aug 8, Sep 5, Oct 10, Oct 24, Nov 7, More...
Queen of the Mississippi Cruises10 Night - Ohio River Cruise from St. Louis to Pittsburgh, PA
Starting in St. Louis, MO; with stops in Cape Girardeau, MO; Paducah, KY; Henderson, KY; Louisville, KY; Cincinnati, OH; Maysville, KY; Marietta, OH; Pittsburgh, PA
2020 Sails: Aug 2, 2021: Aug 10, Aug 30, Sep 19, More...


United States River Cruise Departures
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