New Orleans Cruise Departures
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
5 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Jun 8, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, Aug 31, Sep 5, Sep 14, Sep 19, Sep 28, Oct 3, Oct 12, Oct 17, Oct 26, Oct 31, Nov 9, Nov 14, Nov 23, More...
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 9, More...
14 Night - The Big Easy to the Gateway City
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jun 13, 2028: Jul 11, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Jun 16, Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, More...4 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, More...11 Night - Mississippi River Gateway Cruise
Starting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Day of River Cruising, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of River Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2026 Sails: Jun 22, More...
7 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Belize, Isla Tropicale, Roatan, New Orleans, La
2026 Sails: Jun 28, Jul 12, Aug 23, Nov 8, 2027: Dec 26, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jul 7, Aug 18, Sep 1, 2027: Apr 13, Oct 1, Nov 26, 2028: Oct 31, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, More...7 Night - Bahamas
Starting in New Orleans, La, Key West, FL, Celebration Key, the Bahamas, Nassau, Bahamas, New Orleans, La
2026 Sails: Jul 19, Aug 16, Sep 13, Oct 11, More...
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.
5 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Jun 8, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, Aug 31, Sep 5, Sep 14, Sep 19, Sep 28, Oct 3, Oct 12, Oct 17, Oct 26, Oct 31, Nov 9, Nov 14, Nov 23, More...
22 Night - Complete Mississippi River CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jun 12, 2027: Jun 11, 2028: Jun 9, More...
14 Night - The Big Easy to the Gateway CityStarting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Greenville, Mississippi, Scenic Sailing Lower Mississippi, Memphis, Tennessee, Scenic Sailing Upper Mississippi, Paducah, Kentucky, Cape Girardeau, Missouri, St Louis, Missouri, Alton, Illinois
2026 Sails: Jun 13, 2028: Jul 11, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Jun 16, Oct 12, Nov 1, Nov 7, Nov 13, Nov 19, Nov 25, Dec 1, 2027: Mar 22, Mar 28, Apr 3, Apr 9, Apr 15, Apr 21, Apr 27, May 3, May 9, May 15, May 21, May 27, Jun 2, Jun 8, Jun 14, Jun 20, More...
4 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, Feb 11, Feb 25, Mar 11, Mar 25, Apr 8, Apr 22, May 6, More...
11 Night - Mississippi River Gateway CruiseStarting in New Orleans, La, Cruising the Mississippi River, Oak Alley, LA, Day of River Cruising, Vicksburg, MS, Day of River Cruising, Memphis, TN, Day of River Cruising, Paducah, KY, Day of River Cruising, Louisville, KY
2026 Sails: Jun 22, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Belize, Isla Tropicale, Roatan, New Orleans, La
2026 Sails: Jun 28, Jul 12, Aug 23, Nov 8, 2027: Dec 26, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jul 7, Aug 18, Sep 1, 2027: Apr 13, Oct 1, Nov 26, 2028: Oct 31, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, May 30, Jun 13, More...
7 Night - BahamasStarting in New Orleans, La, Key West, FL, Celebration Key, the Bahamas, Nassau, Bahamas, New Orleans, La
2026 Sails: Jul 19, Aug 16, Sep 13, Oct 11, More...
