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New Orleans Cruise Departures

Cruises that depart from North America: United States: Louisiana: New Orleans

Cruises that visit New Orleans

See all River Cruises that depart from New Orleans

Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.


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American Duchess Cruises8 Night - A Taste of the True South Lower Mississippi River Cruise from New Orleans to Memphis
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Memphis, TN
2020 Sails: Nov 1, Nov 15, Nov 29, More...
RCL Majesty of the Seas Cruise Ship7 Night - Bahamas & Perfect Day Cruise
Starting in New Orleans with stops in Key West, Nassau, Perfect Day at Cococay
2020 Sails: Nov 7, Nov 21, Nov 28, Dec 26, 2021: Jan 30, Feb 13, Feb 27, Mar 6, Mar 13, Apr 3, Apr 10, Apr 17, Apr 24, May 1, May 15, May 29, Jun 5, Jun 26, Jul 10, Jul 24, Jul 31, Aug 7, Aug 21, Sep 4, More...
American Queen Cruises7 Night - Charms of the South Cruise from New Orleans to Memphis - American Queen
Starting in New Orleans; with stops in Nottoway Plantation; St. Francisville; Natchez; Vicksburg; Tunica, MS; Memphis, TN
2020 Sails: Nov 8, Nov 22, Dec 6, More...
Queen of the Mississippi Cruises7 Night - Mississippi River from New Orleans, LA to Memphis, TN
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Baton Rouge, Louisiana; St. Francisville, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; Memphis, Tennessee
2020 Sails: Nov 14, 2021: Mar 13, Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Jun 19, Jul 3, Jul 17, Nov 13, Nov 27, More...
RCL Majesty of the Seas Cruise Ship7 Night - Western Caribbean Cruise
Starting in New Orleans with stops in Cozumel, Puerto Costa Maya, Belize City
2020 Sails: Nov 14, More...
American Countess Cruises6 Night - Charms of the South from New Orleans to Memphis - American Countess
Starting in New Orleans, LA; with stops in Nottoway Plantation; St. Francisville, LA; Natchez, MS; Vicksburg, MS; Port of the Mississippi Delta; Memphis, TN
2020 Sails: Nov 15, More...
NCL Norwegian Breakaway Cruises7 Night - Western Caribbean from New Orleans
Starting in New Orleans with stops in Costa Maya, Harvest Caye, Roatan, Cozumel
2020 Sails: Nov 22, Nov 29, Dec 6, Dec 13, Dec 20, Dec 27, 2021: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Mar 28, Apr 4, More...
Queen of the Mississippi Cruises7 Night - Mississippi River from New Orleans, LA to New Orleans, LA
Starting in New Orleans, Louisiana; with stops in Oak Alley, Louisiana; Natchez, Mississippi; Vicksburg, Mississippi; St. Francisville, Louisiana; Baton Rouge, Louisiana; Houmas House, Louisiana; New Orleans, Louisiana
2020 Sails: Nov 28, Dec 5, 2021: Dec 20, Dec 28, More...
American Countess Cruises7 Night - Southern Sampler Roundtrip from New Orleans
Starting in New Orleans; with stops in St. Francisville; Natchez; Vicksburg; Baton Rouge; Nottoway Plantation; New Orleans
2020 Sails: Nov 29, More...
RCL Majesty of the Seas Cruise Ship7 Night - Bahamas & Perfect Day Cruise
Starting in New Orleans with stops in Perfect Day at Cococay, Grand Bahama Island, Key West
2020 Sails: Dec 5, Dec 12, 2021: Feb 6, Mar 20, Jun 19, Jul 3, Jul 17, Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, More...


New Orleans Cruise Departures

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