New Orleans Cruise Departures
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, More...
7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 28, Mar 6, Mar 12, Dec 12, 2027: Mar 2, Mar 8, Mar 14, Mar 20, Dec 10, Dec 16, 2028: Feb 17, Feb 23, Mar 14, Mar 20, Mar 26, Apr 1, More...
7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, More...
7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, New Orleans, La
2026 Sails: Mar 8, More...
4 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, More...7 Night - Western Caribbean - New Orleans
Starting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Mar 15, Mar 29, Apr 19, May 3, More...5 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Mar 16, Mar 21, Mar 30, Apr 4, Apr 13, Apr 18, Apr 27, May 2, May 11, May 16, May 25, May 30, Jun 8, Jun 13, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, More...11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
7 Night - Western Caribbean
Starting in New Orleans, La, Cozumel, Mexico, Belize, Mahogany Bay, Roatan, New Orleans, La
2026 Sails: Mar 22, May 3, More...
Cruises that depart from North America: United States: Louisiana: New Orleans
Cruises that visit New Orleans
See all River Cruises that depart from New Orleans
Click on a cruise ship itinerary sailing from New Orleans (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just New Orleans), please visit: Cruise Search or try our Virtual Cruise Advisor™.
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 24, Mar 10, Mar 24, Apr 7, Apr 21, May 5, May 19, Jun 2, Jul 14, Nov 3, 2027: Feb 23, Mar 9, Mar 23, Apr 6, Apr 20, May 4, May 18, Jun 1, Jun 15, Jun 29, Oct 5, Oct 19, Nov 2, 2028: Feb 22, More...
7 Night - Highlights of the Mississippi CruiseStarting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
2026 Sails: Feb 28, Mar 6, Mar 12, Dec 12, 2027: Mar 2, Mar 8, Mar 14, Mar 20, Dec 10, Dec 16, 2028: Feb 17, Feb 23, Mar 14, Mar 20, Mar 26, Apr 1, More...
7 Night - Gulf Coast CruiseStarting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Mar 1, Mar 13, Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
8 Night - Lower Mississippi River CruiseStarting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, New Orleans, La
2026 Sails: Mar 8, More...
4 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, New Orleans, La
2026 Sails: Mar 12, Mar 26, Apr 9, Apr 23, May 7, May 21, Jun 4, Jun 18, Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, Oct 22, Nov 5, Nov 19, Dec 3, Dec 17, Dec 26, 2027: Jan 14, Jan 28, More...
7 Night - Western Caribbean - New OrleansStarting in New Orleans, La, Cozumel, Mexico, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Costa Maya, Mexico, New Orleans, La
2026 Sails: Mar 15, Mar 29, Apr 19, May 3, More...
5 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Progreso, Yucatan, Mexico, New Orleans, La
2026 Sails: Mar 16, Mar 21, Mar 30, Apr 4, Apr 13, Apr 18, Apr 27, May 2, May 11, May 16, May 25, May 30, Jun 8, Jun 13, Jun 22, Jun 27, Jul 6, Jul 11, Jul 20, Jul 25, Aug 3, Aug 8, Aug 17, Aug 22, More...
11 Night - Mississippi Explorer CruiseStarting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
2026 Sails: Mar 18, Apr 7, More...
7 Night - Western CaribbeanStarting in New Orleans, La, Cozumel, Mexico, Belize, Mahogany Bay, Roatan, New Orleans, La
2026 Sails: Mar 22, May 3, More...
