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American Serenade
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7 Night - Highlights of the Mississippi Cruise
Starting in New Orleans, La, Cruising the Historic Mississippi River, Oak Alley, LA, Baton Rouge, LA, Natchez / Vicksburg, MS, St Francisville, LA, New Orleans, La
8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, Nov 9, Nov 23, Dec 7, Dec 21, 2028: Feb 18, Mar 3, Mar 17, Mar 31, Apr 28, More...
8 Night - Lower Mississippi River Cruise
Starting in Memphis, TN, Cruising the Lower Mississippi River, Cleveland, MS, Vicksburg, MS, Natchez, MS, St Francisville, LA, Day of River Cruising, Oak Alley, LA, New Orleans, La
2026 Sails: Mar 27, Apr 10, Apr 24, May 8, May 22, Jun 5, Oct 22, 2027: Feb 26, Mar 12, Mar 26, Apr 9, Apr 23, May 7, Jun 4, Nov 16, Nov 30, Dec 14, Dec 28, 2028: Feb 11, Feb 25, Mar 10, Mar 24, Apr 21, More...
8 Night - Upper Mississippi River Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Day of River Cruising, Dubuque, IA, Davenport, IA, Hannibal, MO, St Louis, MO / Alton, IL, Alton, IL / St Louis, MO
2026 Sails: Jul 3, Jul 17, Jul 31, Aug 14, Aug 28, Sep 11, 2027: Jul 2, Jul 16, Jul 30, Aug 13, Aug 27, Sep 10, 2028: Jun 30, Jul 14, Jul 28, Aug 11
8 Night - Upper Mississippi River Cruise
Starting in St Louis, MO / Alton, IL, Cruising the Mississippi River, Hannibal, MO, Day of Cruising, Muscatine, IA, Dubuque, IA, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Jul 10, Jul 24, Aug 7, Aug 21, Sep 4, Sep 18, 2027: Jul 9, Jul 23, Aug 6, Aug 20, Sep 3, Sep 17, 2028: Jul 7, Jul 21, Aug 4, Aug 18
8 Night - Arkansas River Cruise
Starting in Memphis, TN, Day of Cruising, Cleveland, MS, Day of River Cruising, Little Rock, AR, Fort Smith / Van Buren, AR, Muskogee, OK, Tulsa, OK
8 Night - Arkansas River Cruise
Starting in Tulsa, OK, Day of Cruising, Muskogee, OK, Fort Smith / Van Buren, AR, Little Rock, AR, Day of River Cruising, Cleveland, MS, Memphis, TN
11 Night - Mississippi Explorer Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, St Francisville, LA, Natchez, MS, Day of Cruising, Vicksburg, MS, Day of River Cruising, Cleveland, MS, Tunica, MS, Memphis, TN
11 Night - Mississippi Explorer Cruise
Starting in Memphis, TN, Cruising the Mississippi River, Tunica, MS, Day of River Cruising, Cleveland, MS, Vicksburg, MS, Day of River Cruising, Natchez, MS, St Francisville, LA, Oak Alley, LA, New Orleans, La
2027 Sails: Oct 18
15 Night - Grand Heartland Cruise
Starting in St Paul, MN, Cruising the Mississippi River, La Crosse, WI, Dubuque, IA, Davenport, IA, Day of Cruising, Hannibal, MO, Day of River Cruising, St Louis, MO, Memphis, TN, Tunica, MS, Day of Cruising, Vicksburg, MS, Natchez, MS, Baton Rouge, LA, New Orleans, La
22 Night - Complete Mississippi River Cruise
Starting in New Orleans, La, Day of River Cruising, Oak Alley, LA, Baton Rouge, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Greenville, MS, Tunica, MS, Memphis, TN, Day of Cruising, Cape Girardeau, MO, Day of River Cruising, St Louis, MO, Day of River Cruising, Hannibal, MO, Day of River Cruising, Muscatine, IA, Dubuque, IA, Day of River Cruising, Winona, MN, Red Wing, MN, St Paul, MN
About American Serenade
Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.
American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. The new ship also features an on board fitness center and many spacious lounges where you can relax after the day's adventures.