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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Royal Caribbean, Explorer of the Seas
Explorer of the Seas5 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Feb 16, Mar 16, Apr 13, More...
Royal Caribbean, Navigator of the Seas
Navigator of the Seas6 Night - Cabo & Ensenada Cruise
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Feb 16, More...
Margaritaville at Sea, Margaritaville Islander
Margaritaville Islander6 Night - Mexico & Western Caribbean
Starting in Port Tampa Bay, Belize, Roatan, Honduras, Cozumel, Mexico, Port Tampa Bay
2026 Sails: Feb 17, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem11 Night - Caribbean
Starting in Jacksonville, Florida, Puerto Plata, Dominican Republic, Tortola, British Virgin Islands, St Johns AG, Antigua, Basseterre, Saint Kitts / Nevis, San Juan, Pr, Great Stirrup Cay, Bahamas, Jacksonville, Florida
2026 Sails: Feb 17, More...
Carnival Cruise Lines, Carnival Freedom
Carnival Freedom4 Night - Bahamas
Starting in Port Canaveral (Orlando), Fl, Princess Cays, the Bahamas, Celebration Key, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Feb 19, Mar 19, Jun 25, Aug 6, More...
Queen Elizabeth21 Night - Caribbean Roundtrip from Miami
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL, Grand Turk, Turks and Caicos Islands, Montego Bay, Jamaica, Belize City, Belize, Cozumel, Mexico, Miami, FL
2026 Sails: Feb 19, More...
Queen Elizabeth12 Night - Eastern Caribbean
Starting in Miami, FL, San Juan, Puerto Rico, St Johns AG, Antigua, Castries, St Lucia, Bridgetown, Barbados, Philipsburg, St Maarten, Road Town, Tortola, Miami, FL
2026 Sails: Feb 19, Mar 12, Apr 2, More...
Margaritaville at Sea, Margaritaville Paradise
Margaritaville Paradise4 Night - Bahamas Duo
Starting in Port of Palm Beach, Freeport, Grand Bahama, Nassau, Bahamas, Port of Palm Beach
2026 Sails: Feb 19, Nov 9, Nov 16, More...
American Cruise Lines, American Serenade
American Serenade8 Night - Lower Mississippi River Cruise
Starting in New Orleans, La, Cruising the Lower Mississippi River, Oak Alley, LA / Houmas House, LA, St Francisville, LA, Natchez, MS, Vicksburg, MS, Cleveland, MS, Memphis, TN
2026 Sails: Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 1, May 15, May 29, Oct 15, 2027: Feb 19, Mar 5, Mar 19, Apr 2, Apr 16, Apr 30, May 14, May 28, Nov 9, Nov 23, Dec 7, 2028: Feb 19, Mar 4, Mar 18, Apr 1, More...
Carnival Cruise Lines, Carnival Conquest
Carnival Conquest3 Night - Bahamas
Starting in Miami, Fl, Celebration Key, the Bahamas, Miami, Fl
2026 Sails: Feb 20, More...

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United States Cruise Departures