United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Carnival Cruise Lines, Carnival Freedom

3 Night - Bahamas
Starting in Port Canaveral (Orlando), Fl, Nassau, Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Aug 15, More...

Carnival Cruise Lines, Carnival Panorama

8 Night - Mexican Riviera
Starting in Long Beach (Los Angeles), Ca, Cabo San Lucas, Mexico, La Paz, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Long Beach (Los Angeles), Ca
2026 Sails: Aug 15, More...

HX Expeditions Tours, MS Fridtjof Nansen Tours

24 Night - Arctic from Bayonne, Newark (Cape Liberty) to Seattle
Starting in Newark Airport, Nuuk, Evighed Fjord, Sisimiut, Ilulissat, Pond Inlet, Dundas Harbour, Croker Bay, Beechey Island, Fort Ross, Bellot Strait, Coningham Bay, James Ross Strait, Gjoa Haven, Cambridge Bay, Ulukhaktok, Herschel Island, Nome, Seattle
2026 Sails: Aug 15, More...

Margaritaville at Sea, Margaritaville Islander

7 Night - Jamaica & Western Caribbean
Starting in Port Tampa Bay, Cozumel, Mexico, Montego Bay, Jamaica, George Town, Grand Cayman, Port Tampa Bay
2026 Sails: Aug 15, Aug 29, More...

MSC Cruises, MSC World America

14 Night - Caribbean and Antilles
Starting in Miami, Florida, Isla De Roatan, Honduras, Costa Maya, Mexico, Cozumel, Mexico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Puerto Plata, Dominican Republic, San Juan, Puerto Rico, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2027: Jan 2, Jan 16, Jan 30, Feb 13, Feb 27, Mar 13, Mar 27, More...

Princess Cruises, Regal Princess

7 Night - Eastern Caribbean with St. Thomas
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Aug 15, More...

Princess Tours, Coral Princess Tours

11 Night - Denali Explorer - Tour Gb4
Starting in Fairbanks, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 15, Aug 29, More...

Princess Tours, Coral Princess Tours

11 Night - Denali Explorer - Tour Fb4
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 15, Aug 29, More...

Princess Tours, Discovery Princess Tours

14 Night - Off the Beaten Path - Tour Pb7
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 15, More...

Royal Caribbean, Adventure of the Seas

6 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, George Town, Grand Cayman, Falmouth, Jamaica, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Aug 15, More...

<= Back

More =>

United States Cruise Departures