United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Tours, Coral Princess Tours

13 Night - Denali Explorer - Tour Kb6
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 13, Aug 27, More...

Princess Tours, Coral Princess Tours

13 Night - Connoisseur Escorted - Tour Sb6
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 13, Aug 27, More...

Princess Tours, Coral Princess Tours

13 Night - Off the Beaten Path - Tour Mb6
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Aug 13, Aug 27, More...

Royal Caribbean, Freedom of the Seas

4 Night - Bahamas & Perfect Day Cruise
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Bimini, Bahamas, Miami, Florida
2026 Sails: Aug 13, More...

Royal Caribbean, Harmony of the Seas

5 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Aug 13, Sep 10, Oct 8, Nov 5, More...

Virgin Voyages, Brilliant Lady

7 Night - Alaska : Inside Passage & Glacial Fjords
Starting in Seattle, Washington, Inside Passage (Cruising), Ketchikan, Alaska, Sitka, Alaska, Endicott Arm and Dawes Glacier (Cruising), Prince Rupert, Canada, Seattle, Washington
2026 Sails: Aug 13, More...

American Cruise Lines, American Melody

8 Night - Upper Mississippi River Cruise
Starting in St Louis, MO / Alton, IL, Cruising the Mississippi River, Hannibal, MO, Day of Cruising, Muscatine, IA, Dubuque, IA, Winona, MN, Red Wing, MN, St Paul, MN
2026 Sails: Aug 14, Aug 28, Sep 11, Sep 25, Oct 9, 2027: Jul 30, Aug 13, Aug 27, Sep 10, Sep 24, Oct 8, 2028: Jul 1, Jul 14, Jul 28, Aug 11, Aug 25, Sep 8, Sep 22, More...

Carnival Cruise Lines, Carnival Glory

3 Night - Bahamas
Starting in Port Canaveral (Orlando), Fl, Celebration Key, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Aug 14, Sep 11, Oct 9, Oct 16, Nov 6, Nov 20, Nov 27, Dec 28, 2027: Feb 12, Feb 19, Mar 26, Apr 9, Apr 16, Apr 23, Jul 2, Aug 13, Dec 17, 2028: Jan 28, Apr 7, Apr 21, More...

Disney Cruise Line, Disney Fantasy

5 Night - Bahamian Cruise from Port Canaveral
Starting in Port Canaveral, Castaway Cay, Disney Lookout Cay, Nassau, Port Canaveral
2026 Sails: Aug 14, Aug 28, Sep 11, Sep 25, Oct 4, Oct 23, Nov 1, Nov 6, Nov 15, Nov 29, Dec 13, 2027: Jan 10, Feb 12, Feb 21, Feb 26, Mar 7, Mar 12, Mar 21, Apr 4, Apr 9, May 7, More...

Norwegian Cruise Line, Norwegian Joy

10 Night - Alaska - Seattle
Starting in Seattle, Wa, Juneau, Ak, Skagway, Ak, Cruise Hubbard Glacier, Ak, Sitka, Ak, Icy Strait Point, Ak, Ketchikan (Ward Cove), Ak, Victoria CA, Canada, Seattle, Wa
2026 Sails: Aug 14, More...

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United States Cruise Departures