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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Royal Caribbean International, Oasis of the Seas
Oasis of the Seas Cruise Ship8 Night - Southern Caribbean & Perfect Day
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Willemstad AN, Curacao, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, More...
Royal Caribbean International, Rhapsody of the Seas
Rhapsody of the Seas Cruise Ship7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Roatan, Honduras, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Jan 24, Feb 21, Mar 21, More...
Royal Caribbean International, Vision of the Seas
Vision of the Seas Cruise Ship12 Night - Southern Caribbean Cruise
Starting in Baltimore, Maryland, St Croix, US Virgin Islands, Basseterre, St Kitts and Nevis, Fort-De-France, Martinique, Roseau, Dominica, Philipsburg, St Maarten, Baltimore, Maryland
2026 Sails: Jan 24, Mar 21, Apr 18, More...
Virgin Voyages, Resilient Lady
Resilient Lady Cruises7 Night - Western Caribbean & Bimini Beach Club
Starting in Miami, Ocho Rios, Jamaica, George Town, Cayman Islands, The Beach Club at Bimini, Bahamas, Miami
2026 Sails: Jan 24, Feb 21, Apr 4, Apr 11, Apr 25, More...
Celebrity Cruises, Celebrity Beyond
Celebrity Beyond Cruises7 Night - Tortola, San Juan & Puerto Plata
Starting in Miami, Florida, Tortola, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Miami, Florida
2026 Sails: Jan 25, Feb 8, Mar 8, Mar 22, Apr 5, Apr 19, More...
Celebrity Cruises, Celebrity Eclipse
Celebrity Eclipse Cruise Ship6 Night - Grand Cayman, Mexico & Key West
Starting in Fort Lauderdale, Florida, Key West, Florida, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Jan 25, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel Cruises7 Night - Usvi & Puerto Plata Cruise
Starting in Fort Lauderdale, Florida, Puerto Plata, Dominican Republic, Charlotte Amalie, St Thomas, Philipsburg, St Maarten, Fort Lauderdale, Florida
2026 Sails: Jan 25, Feb 8, Feb 22, Mar 8, Mar 22, Apr 5, Apr 19, More...
Explora Journeys, EXPLORA II
EXPLORA II Cruises20 Night - An Extended Journey to Delightful Island Towns and Tropical Treasures
Starting in Miami, Puerto Plata, Dominican Republic, Kralendijk, Oranjestad, Willemstad AN, Ocean Cay, Miami, Charlotte Amalie (Saint Thomas), Pointe-a-Pitre, Castries, Little Bay, St John VI (Cruz Bay), US Virgin Islands, Miami
2026 Sails: Jan 25, More...
EXPLORA II Cruises10 Night - A Journey from Miami to Miami
Starting in Miami, Puerto Plata, Dominican Republic, Kralendijk, Oranjestad, Willemstad AN, Ocean Cay, Miami
2026 Sails: Jan 25, More...
MSC Cruises, MSC Divina
MSC Divina Cruises7 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocean Cay Msc Marine Reserve, Bahamas, Cozumel, Mexico, George Town, Cayman Islands, Ocho Rios, Jamaica, Miami, Florida
2026 Sails: Jan 25, More...

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United States Cruise Departures