United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Cruises, Majestic Princess

7 Night - Canada & New England with Saint John
Starting in New York City (Manhattan or Brooklyn), New York, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, New York City (Manhattan or Brooklyn), New York
2026 Sails: Oct 24, More...

Princess Cruises, Regal Princess

7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Cozumel, Mexico, Belize City, Belize, Roatan (Isla Tropicale), Honduras, Fort Lauderdale, Florida
2026 Sails: Oct 24, More...

Princess Cruises, Star Princess

7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Roatan (Isla Tropicale), Honduras, Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Oct 24, Nov 7, Nov 21, Dec 5, 2027: Jan 2, Jan 16, Jan 30, Feb 13, Mar 13, More...

Princess Cruises, Star Princess

14 Night - Eastern / Western Caribbean Adventurer with Celebration Key
Starting in Fort Lauderdale, Florida, Roatan (Isla Tropicale), Honduras, Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida, Celebration Key, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 24, More...

Royal Caribbean, Adventure of the Seas

6 Night - Western Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Puerto Costa Maya, Mexico, Cozumel, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Oct 24, More...

Royal Caribbean, Enchantment of the Seas

7 Night - Western Caribbean & Perfect Day
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Tampa, Florida
2026 Sails: Oct 24, Nov 8, More...

Royal Caribbean, Harmony of the Seas

5 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Oct 24, 2027: Jan 23, Feb 20, May 29, More...

Royal Caribbean, Icon of the Seas

Deal link -> Special

7 Night - Perfect Day Cococay & East Carib
Starting in Miami, Florida, Philipsburg, St Maarten, Charlotte Amalie, St Thomas, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2027: Apr 24, May 8, May 15, Jun 5, Jun 19, Jun 26, Jul 10, Jul 17, Jul 31, More...

Royal Caribbean, Independence of the Seas

5 Night - Bermuda Getaway Cruise
Starting in Cape Liberty, Nj (Ny Metro), Royal Naval Dockyard, Bermuda, Cape Liberty, Nj (Ny Metro)
2026 Sails: Oct 24, 2027: May 27, Jun 5, Jun 19, Jun 24, Jul 3, Jul 17, Jul 22, Jul 31, Aug 14, Aug 19, Aug 28, Sep 11, Sep 25, Oct 9, Oct 23, More...

Royal Caribbean, Radiance of the Seas

5 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Oct 24, 2028: Apr 10, More...

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United States Cruise Departures