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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

MSC Cruises, MSC Seashore
MSC Seashore Cruises4 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Ocean Cay Msc Marine Reserve, Bahamas, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Jan 25, Feb 22, Mar 22, More...
Norwegian Cruise Line, Norwegian Bliss
Norwegian Bliss Cruises7 Night - Mexican Riviera - Los Angeles
Starting in Los Angeles, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Jan 25, Mar 8, Mar 15, Mar 22, Mar 29, Apr 5, Apr 12, More...
Norwegian Cruise Line, Norwegian Dawn
Norwegian Dawn Cruise Ship10 Night - Southern Caribbean - Tampa
Starting in Tampa, Fl, Cabo Rojo, Dominican Republic, Oranjestad, Aruba, Willemstad AN, Netherlands Antilles, Falmouth, Jamaica, George Town, Cayman Islands, Tampa, Fl
2026 Sails: Jan 25, More...
Norwegian Cruise Line, Norwegian Prima
Norwegian Prima Cruises7 Night - Western Caribbean - Port Canaveral
Starting in Orlando Beaches / Port Canaveral, Fl, Great Stirrup Cay, Bahamas, Ocho Rios, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Orlando Beaches / Port Canaveral, Fl
2026 Sails: Jan 25, Feb 22, More...
Princess Cruises, Majestic Princess
Majestic Princess Cruises6 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Belize City, Belize, Cozumel, Mexico, Costa Maya (Mahahual), Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 25, More...
Princess Cruises, Regal Princess
Regal Princess Cruise Ship7 Night - Western Caribbean with Mexico
Starting in Galveston, Texas, Cozumel, Mexico, Belize City, Belize, Costa Maya (Mahahual), Mexico, Galveston, Texas
2026 Sails: Jan 25, More...
Princess Cruises, Sky Princess
Sky Princess Cruises14 Night - Eastern Caribbean Adventurer
Starting in Port Canaveral (Orlando), Florida, Amber Cove, Dominican Republic, St Maarten, San Juan, Puerto Rico, Grand Turk, Turks and Caicos, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Port Canaveral (Orlando), Florida
2026 Sails: Jan 25, More...
Princess Cruises, Sky Princess
Sky Princess Cruises8 Night - Eastern Caribbean with Puerto Rico
Starting in Port Canaveral (Orlando), Florida, Amber Cove, Dominican Republic, St Maarten, San Juan, Puerto Rico, Grand Turk, Turks and Caicos, Port Canaveral (Orlando), Florida
2026 Sails: Jan 25, More...
Princess Cruises, Sun Princess
Sun Princess Cruise Ship14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida, Cozumel, Mexico, Roatan (Mahogany Bay, Honduras), Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 25, More...
Princess Cruises, Sun Princess
Sun Princess Cruise Ship7 Night - Eastern Caribbean with St. Thomas
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Jan 25, Feb 22, More...

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United States Cruise Departures