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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Norwegian Cruise Line, Norwegian Encore
Norwegian Encore Cruises7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Roatan Bay Islands, Honduras, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2026 Sails: Jan 24, More...
Norwegian Cruise Line, Norwegian Jade
Norwegian Jade Cruise Ship7 Night - Mexican Riviera - San Diego
Starting in San Diego, Ca, Puerto Vallarta, Mexico, Mazatlan, Mexico, Cabo San Lucas, Mexico, San Diego, Ca
2026 Sails: Jan 24, Jan 31, More...
Norwegian Cruise Line, Norwegian Viva
Norwegian Viva Cruises14 Night - Caribbean
Starting in Galveston, Texas, Ocho Rios, Jamaica, San Juan, Pr, Philipsburg, St Maarten, Netherland Antilles, St Johns AG, Antigua, St Thomas, Vi, Puerto Plata, Dominican Republic, George Town, Cayman Islands, Cozumel, Mexico, Galveston, Texas
2026 Sails: Jan 24, More...
Princess Cruises, Royal Princess
Royal Princess Cruise Ship7 Night - Mexican Riviera
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, Mar 14, Mar 21, Apr 11, Apr 18, More...
Princess Cruises, Star Princess
Star Princess Cruise Ship14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Roatan (Mahogany Bay, Honduras), Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida, Princess Cays, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Fort Lauderdale, Florida
2026 Sails: Jan 24, More...
Princess Cruises, Star Princess
Star Princess Cruise Ship7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Roatan (Mahogany Bay, Honduras), Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 24, More...
Explorer of the Seas Cruise Ship5 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Cozumel, Mexico, Puerto Costa Maya, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Jan 24, Mar 7, Apr 4, Apr 18, More...
Royal Caribbean International, Freedom of the Seas
Freedom of the Seas Cruise Ship5 Night - Caribbean Getaway Cruise
Starting in Miami, Florida, Nassau, Bahamas, George Town, Grand Cayman, Miami, Florida
2026 Sails: Jan 24, More...
Royal Caribbean International, Grandeur of the Seas
Grandeur of the Seas Cruise Ship7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Belize City, Belize, Roatan, Honduras, Cozumel, Mexico, Tampa, Florida
2026 Sails: Jan 24, Feb 7, Feb 21, Mar 21, Apr 4, More...
Icon of the Seas Cruises7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Jan 24, Feb 7, Feb 21, Mar 7, Mar 21, Apr 4, Apr 18, May 9, May 23, Jun 13, Jul 4, Jul 25, Aug 15, Sep 5, Sep 26, Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, More...

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United States Cruise Departures