Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Scenic Luxury, Scenic Eclipse

13 Night - Ancient Kingdoms and Natural Treasures : Panama to Chile
Starting in Panama City, Panama, Darien National Park / Playa del Muerto, Panama, Utria National Park / Ensenada de Utria, Colombia, Manta, Ecuador, Salaverry, Peru, Paracas, Peru, Pinguino de Humboldt National Reserve, Valparaiso, Chile
2027 Sails: Oct 31, More...

Viking Ocean, Viking Mars

14 Night - Panama Canal & Central America
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Montego Bay, Sail the Caribbean Sea, Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Roatan, Belize City, Cozumel, Mexico, Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Nov 5, Dec 9, Dec 23, 2028: Jan 26, Feb 9, More...

Crystal Cruises, Crystal Serenity

41 Night - South America
Starting in Buenos Aires, Punta Del Este, Puerto Madryn, Port Stanley, Falkland Islands, Ushuaia, Punta Arenas, Cruising the Chilean Fjords, Laguna San Raphael, Puerto Chacabuco, Castro, Puerto Montt, Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 11, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Kralendijk, Bonaire, Oranjestad, Aruba, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida
2027 Sails: Nov 11, More...

Princess Cruises, Caribbean Princess

12 Night - Panama Canal with Costa Rica & Caribbean
Starting in Fort Lauderdale, Florida, Aruba, Cartagena CO, Panama Canal Partial Transit New Locks, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida
2027 Sails: Nov 11, 2028: Feb 12, Mar 25, More...

Lindblad Expeditions, National Geographic Quest

7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Panama City, Panama / Colon / Embark Ship, Portobelo, Guna Yala Archipelago, Capurgana and Sapzurro, Colombia, Santa Cruz de Lorica / San Antero / Tuchin, Cispata Bay / Sanguare Natural Reserve, Cartagena CO, Colombia / Disembark Ship
2027 Sails: Nov 12, More...

Lindblad Expeditions, National Geographic Quest

7 Night - Panama and Colombia : Exploring the Caribbean Coast
Starting in Cartagena CO, Colombia / Embark Ship, Sanguare Natural Reserve / Cispata Bay, San Antero / Santa Cruz de Lorica / Tuchin, Capurgana and Sapzurro, Colombia, Guna Yala Archipelago, Portobelo, Panama City, Panama / Disembark Ship
2027 Sails: Nov 19, More...

Viking Ocean, Viking Mars

10 Night - Classic Panama Canal Passage
Starting in Fort Lauderdale, Florida, Sail the Caribbean Sea, Merida (Progreso), Cozumel, Mexico, Belize City, Sail the Caribbean Sea, Puerto Limon, Colon, Scenic Sailing Panama Canal, Panama City (Fuerte Amador)
2027 Sails: Nov 19, 2028: Jan 6, More...

MSC Cruises, MSC Poesia

21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Kralendijk, Bonaire, Oranjestad, Aruba, Willemstad AN, Curacao, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida
2027 Sails: Nov 21, More...

Carnival Cruise Lines, Carnival Sunshine

10 Night - Caribbean & Panama
Starting in Galveston, Tx, Isla Tropicale, Roatan, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Galveston, Tx
2027 Sails: Nov 22, More...

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