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Panama City Cruises

Cruises that visit Central America: Panama: Panama City

Cruises that depart from Panama City

Click on a cruise ship itinerary that visits Panama City (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama City), please visit: Cruise Search or try our Virtual Cruise Advisor™.


MS Roald Amundsen Cruises14 Night - Caribbean Sea - Hidden Highlights and Sailing Through the Panama Canal (Itinerary 1) from Nassau to Panama City
Starting in Nassau, The Bahamas with stops in Inagua Islands, The Bahamas; Cockburn Town, Turks and Caicos; Port Antonio, Jamaica; Montego Bay, Jamaica; George Town, Cayman Islands; Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Sep 25, More...
Safari Voyager Cruises7 Night - Unveiled Wonders - Costa Rica & Panama Cruise from San Jose to Panama City
Starting in San José, Costa Rica; with stops in Curú National Wildlife Refuge; Osa Conservation Area; Golfo Dulce, Costa Rica; Granito de Oro, Coiba National Park; Gulf of Panama | Marine Life Search; Panama City, Panama
2021 Sails: Oct 1, Dec 10, Dec 24, 2022: Oct 1, Dec 10, Dec 24, More...
MS Roald Amundsen Cruises7 Night - Hidden Highlights of the Caribbean from George Town to Panama City
Starting in George Town, Cayman Islands with stops in Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 2, More...
MS Fridtjof Nansen Cruises14 Night - Caribbean Sea - Hidden Highlights and Sailing Through the Panama Canal (Itinerary 2) from Nassau to Panama City
Starting in Nassau, The Bahamas with stops in Inagua Islands, The Bahamas; Cockburn Town, Turks and Caicos; Port Antonio, Jamaica; Montego Bay, Jamaica; George Town, Cayman Islands; Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 5, More...
MS Roald Amundsen Cruises15 Night - Andean Coast - Expedition from Jungle to Desert (Itinerary 1) from Panama City to Valparaiso
Starting in Panama City with stops in Manta, Ecuador; Puerto Bolivar (Machala), Ecuador; Guayaquil, Ecuador; Salaverry, Peru; Callao / Lima, Peru; Paracas, Peru; Matarani, Peru; Arica, Chile; Valparaíso, Chile
2021 Sails: Oct 8, More...
MS Roald Amundsen Cruises11 Night - Panama, Ecuador and Peru - Incan Mysteries and Machu Picchu from Panama City to Lima
Starting in Panama City with stops in Manta, Ecuador; Puerto Bolivar (Machala), Ecuador; Guayaquil, Ecuador; Salaverry, Peru; Callao/Lima/Cusco/Sacred Valley; Sacred Valley/Machu Picchu/Sacred Valley; Sacred Valley/Cusco/Lima; Lima
2021 Sails: Oct 8, More...
MS Roald Amundsen Cruises13 Night - Panama, Ecuador and Peru - Incan Mysteries and Galapagos Islands from Panama City to Guayaquil
Starting in Panama City with stops in Manta, Ecuador; Puerto Bolivar (Machala), Ecuador; Guayaquil, Ecuador; Salaverry, Peru; Callao / Lima, Peru / Quito, Ecuador; Quito/Baltra Island/Santa Cruz Island; Santa Cruz Island/Baltra Island/Guayaquil
2021 Sails: Oct 8, More...
MS Fridtjof Nansen Cruises7 Night - Hidden Highlights of the Caribbean from George Town to Panama City
Starting in George Town, Cayman Islands with stops in Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 12, More...
MS Fridtjof Nansen Cruises15 Night - Andean Coast - Expedition from Jungle to Desert (Itinerary 2) from Panama City to Valparaiso
Starting in Panama City with stops in Manta, Ecuador; Puerto Bolivar (Machala), Ecuador; Guayaquil, Ecuador; Salaverry, Peru; Callao / Lima, Peru; Paracas, Peru; Matarani, Peru; Arica, Chile; Valparaíso, Chile
2021 Sails: Oct 18, More...
MS Fridtjof Nansen Cruises11 Night - Panama, Ecuador and Peru - Incan Mysteries and Machu Picchu from Panama City to Lima
Starting in Panama City with stops in Manta, Ecuador; Puerto Bolivar (Machala), Ecuador; Guayaquil, Ecuador; Salaverry, Peru; Callao/Lima/Cusco/Sacred Valley; Sacred Valley/Machu Picchu/Sacred Valley; Sacred Valley/Cusco/Lima; Lima
2021 Sails: Oct 18, More...


Panama City Cruises

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