Panama Cruises
Cruises that visit Central America: Panama
Cruises that depart from Panama
See all River Cruises that visit Panama
Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island
7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2028 Sails: Jan 2, Jan 23, Feb 27, Mar 5, Apr 9, More...
10 Night - Caribbean & Panama
Starting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Isla Tropicale, Roatan, Galveston, Tx
2028 Sails: Jan 3, Feb 14, Mar 27, More...
65 Night - Wc Liner - Panama Canal, South Pacific & Indian Ocean
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa
2028 Sails: Jan 3, More...115 Night - World Cruise - Roundtrip Ft. Lauderdale
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Santa Cruz de Tenerife, Gibraltar, Siracusa, Italy, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Amalfi Coast (Salerno), Civitavecchia (for Rome), Italy, Corsica (Ajaccio), France, Santa Margherita, Italy, Cannes (for Monte Carlo), France, Barcelona, Spain, Malaga, Spain, Seville (Cadiz), Spain, Tangier, Morocco, Casablanca, Morocco (for Marrakesh), Madeira (Funchal), Portugal, Azores Islands (Ponta Delgada), Portugal
2028 Sails: Jan 3, More...95 Night - World Cruise - Ft. Lauderdale to Rome
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Santa Cruz de Tenerife, Gibraltar, Siracusa, Italy, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Amalfi Coast (Salerno)
2028 Sails: Jan 3, More...15 Night - World Cruise Segment - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2028 Sails: Jan 3, Apr 28, More...
115 Night - Msc World Cruise
Starting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Santa Cruz de Tenerife, Grand Turk Island, Turks and Caicos, Ocean Cay Msc Marine Reserve, Bahamas, Cruising Panama Canal, Balboa, Panama, Manta, Ecuador, Callao (Lima), Peru, Arica, Chile, Hanga Roa (Rapa Nui), Chile, Bounty Bay Passage, Pitcairn, Papeete Tahiti, Nukualofa, Tonga, Noumea, New Caledonia, Auckland, New Zealand, Tauranga, New Zealand, Napier, New Zealand, Picton, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Cairns, Australia, Lombok, Indonesia, Benoa (Bali), Indonesia, Ho Chi Minh City, Vietnam, Halong Bay / Hanoi, Vietnam, Chan May, Viet Nam, Laem Chabang, Thailand, Sihanoukville, Cambodia, Singapore, Port Klang (Kuala Lumpur), Malaysia, Colombo, Sri Lanka, Cochin, India, Mumbai (Bombay), India, Dubai, United Arab Emirates, Muscat, Oman, Aqaba (Petra), Jordan, Suez Canal (Transit), Egypt, Alexandria EG, Egypt, Civitavecchia (Rome), Italy
2028 Sails: Jan 4, More...
14 Night - Aruba, Colombia & Panama Cruise : Oranjestad, Cartagena & Panama City
Starting in Miami, Florida, Oranjestad, Willemstad AN, Cartagena CO, Colon, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima)
2028 Sails: Jan 5, More...176 Night - Azamara World Cruise
Starting in Miami, Florida, Oranjestad, Willemstad AN, Cartagena CO, Colon, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima), Easter Island, Pitcairn Island, Fakarava, Moorea, Papeete, Tahiti, Moorea, Papeete, Tahiti, Bora Bora, Bay of Islands, Auckland, Tauranga, Napier, Wellington, Picton, Christchurch, Dunedin, Milford Sound, Hobart, Tasmania, Eden, Sydney AU, Newcastle AU, Mooloolaba, Queensland, Airlie Beach, Queensland, Cairns, Darwin, Komodo Island, Benoa, Bali, Celukan, Bawang, Bali, Sandakan, Sabah, Puerto Princesa, Palawan, Coron, Manila, Hong Kong, Hue (Da Nang), Ho Chi Minh City, Bangkok (Laem Chabang), Koh Samui, Singapore, Kuala Lumpur, Sabang, Hambantota, Colombo, Cochin, Male, Port Louis, Pointe Des Galets, Taolagnaro, Richards Bay, Durban, Port Elizabeth ZA, Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Praia, Gran Canaria, Canary Islands, Lanzarote, Canary Islands, Agadir, Casablanca, Gibraltar, Malaga, Barcelona, Provence (Marseille), Nice, Porto Venere, Florence / Pisa (Livorno), Porto Santo Stefano, Rome (Civitavecchia), Sorrento, Amalfi, Siracusa, Sicily, Valletta, Kotor, Sibenik, Piran, Venice, Rovinj (Istria), Dubrovnik, Croatia, Corfu, Argostoli, Monemvasia, Santorini, Rhodes, Bodrum, Syros, Athens (Piraeus)
2028 Sails: Jan 5, More...
19 Night - Panama, Peru & Chile Combination Cruise : Panama Canal, Lima & Coquimbo
Starting in Miami, Florida, Cozumel, Mexico, Belize City, Roatan, Puerto Limon, Bocas del Toro, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima), Pisco, Coquimbo, Valparaiso
2028 Sails: Jan 5, More...
Cruises that visit Central America: Panama
Cruises that depart from Panama
See all River Cruises that visit Panama
Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.
Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island
7 Night - Southern Caribbean CruiseStarting in Cartagena CO, Willemstad AN, Curacao, Oranjestad, Aruba, Colon, Panama, Cartagena CO
2028 Sails: Jan 2, Jan 23, Feb 27, Mar 5, Apr 9, More...
10 Night - Caribbean & PanamaStarting in Galveston, Tx, Cozumel, Mexico, Limon, Costa Rica, Colon (Panama Canal), Panama, Isla Tropicale, Roatan, Galveston, Tx
2028 Sails: Jan 3, Feb 14, Mar 27, More...
65 Night - Wc Liner - Panama Canal, South Pacific & Indian OceanStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa
2028 Sails: Jan 3, More...
115 Night - World Cruise - Roundtrip Ft. LauderdaleStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Santa Cruz de Tenerife, Gibraltar, Siracusa, Italy, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Amalfi Coast (Salerno), Civitavecchia (for Rome), Italy, Corsica (Ajaccio), France, Santa Margherita, Italy, Cannes (for Monte Carlo), France, Barcelona, Spain, Malaga, Spain, Seville (Cadiz), Spain, Tangier, Morocco, Casablanca, Morocco (for Marrakesh), Madeira (Funchal), Portugal, Azores Islands (Ponta Delgada), Portugal
2028 Sails: Jan 3, More...
95 Night - World Cruise - Ft. Lauderdale to RomeStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California, Kauai (Nawiliwili), Hawaii, Honolulu, Hawaii, Cross International Date Line, Apia, Western Samoa, Suva, Fiji, Auckland, New Zealand, Napier, New Zealand, Wellington, New Zealand, New Plymouth, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Pointe des Galets, Reunion Island, Port Elizabeth ZA, Mossel Bay, South Africa, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Santa Cruz de Tenerife, Gibraltar, Siracusa, Italy, Corfu, Greece, Dubrovnik, Croatia, Split, Croatia, Kotor, Montenegro, Athens (Piraeus), Greece, Kusadasi, Turkey (for Ephesus), Crete (Chania), Greece, Amalfi Coast (Salerno)
2028 Sails: Jan 3, More...
15 Night - World Cruise Segment - Panama CanalStarting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal Full Transit Historic Locks, Acajutla, El Salvador, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2028 Sails: Jan 3, Apr 28, More...
115 Night - Msc World CruiseStarting in Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France, Barcelona, Spain, Santa Cruz de Tenerife, Grand Turk Island, Turks and Caicos, Ocean Cay Msc Marine Reserve, Bahamas, Cruising Panama Canal, Balboa, Panama, Manta, Ecuador, Callao (Lima), Peru, Arica, Chile, Hanga Roa (Rapa Nui), Chile, Bounty Bay Passage, Pitcairn, Papeete Tahiti, Nukualofa, Tonga, Noumea, New Caledonia, Auckland, New Zealand, Tauranga, New Zealand, Napier, New Zealand, Picton, New Zealand, Wellington, New Zealand, Sydney AU, Australia, Cairns, Australia, Lombok, Indonesia, Benoa (Bali), Indonesia, Ho Chi Minh City, Vietnam, Halong Bay / Hanoi, Vietnam, Chan May, Viet Nam, Laem Chabang, Thailand, Sihanoukville, Cambodia, Singapore, Port Klang (Kuala Lumpur), Malaysia, Colombo, Sri Lanka, Cochin, India, Mumbai (Bombay), India, Dubai, United Arab Emirates, Muscat, Oman, Aqaba (Petra), Jordan, Suez Canal (Transit), Egypt, Alexandria EG, Egypt, Civitavecchia (Rome), Italy
2028 Sails: Jan 4, More...
14 Night - Aruba, Colombia & Panama Cruise : Oranjestad, Cartagena & Panama CityStarting in Miami, Florida, Oranjestad, Willemstad AN, Cartagena CO, Colon, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima)
2028 Sails: Jan 5, More...
176 Night - Azamara World CruiseStarting in Miami, Florida, Oranjestad, Willemstad AN, Cartagena CO, Colon, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima), Easter Island, Pitcairn Island, Fakarava, Moorea, Papeete, Tahiti, Moorea, Papeete, Tahiti, Bora Bora, Bay of Islands, Auckland, Tauranga, Napier, Wellington, Picton, Christchurch, Dunedin, Milford Sound, Hobart, Tasmania, Eden, Sydney AU, Newcastle AU, Mooloolaba, Queensland, Airlie Beach, Queensland, Cairns, Darwin, Komodo Island, Benoa, Bali, Celukan, Bawang, Bali, Sandakan, Sabah, Puerto Princesa, Palawan, Coron, Manila, Hong Kong, Hue (Da Nang), Ho Chi Minh City, Bangkok (Laem Chabang), Koh Samui, Singapore, Kuala Lumpur, Sabang, Hambantota, Colombo, Cochin, Male, Port Louis, Pointe Des Galets, Taolagnaro, Richards Bay, Durban, Port Elizabeth ZA, Cape Town, Luderitz, Walvis Bay, Jamestown, Saint Helena Island, Praia, Gran Canaria, Canary Islands, Lanzarote, Canary Islands, Agadir, Casablanca, Gibraltar, Malaga, Barcelona, Provence (Marseille), Nice, Porto Venere, Florence / Pisa (Livorno), Porto Santo Stefano, Rome (Civitavecchia), Sorrento, Amalfi, Siracusa, Sicily, Valletta, Kotor, Sibenik, Piran, Venice, Rovinj (Istria), Dubrovnik, Croatia, Corfu, Argostoli, Monemvasia, Santorini, Rhodes, Bodrum, Syros, Athens (Piraeus)
2028 Sails: Jan 5, More...
19 Night - Panama, Peru & Chile Combination Cruise : Panama Canal, Lima & CoquimboStarting in Miami, Florida, Cozumel, Mexico, Belize City, Roatan, Puerto Limon, Bocas del Toro, Panama Canal (Cruising), Panama City (Fuerte Amador), Manta, Callao (Lima), Pisco, Coquimbo, Valparaiso
2028 Sails: Jan 5, More...
