Panama Cruise Specials
We've gathered all of the Panama cruise specials ordered by sail date. Click on a special and select a sail date to get a single cruise quote from the cruise agency that posted that particular special. To search through all cruise itineraries (not just Panama cruises) to receive multiple custom cruise options to compare, please visit our Cruise Search page.
Holland America, Nieuw Amsterdam
21 Nights Eastern Caribbean Cruise from $1866 pp plus OBC21 Night - Southern Caribbean & Panama Canal : Abc Islands - Starting in Fort Lauderdale, Florida, Cabo Rojo, Dominican Republic, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Oct 30 Get a Quote
Holland America, Nieuw Amsterdam
12Night Panama Canal DiscoveryCruise Costa Rica Greater Antilles $1114pp12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Nov 8 Get a Quote
Holland America, Nieuw Amsterdam
21 Nights Panama Canal & Southern Caribbean Discovery Cruise from $1618 pp21 Night - Panama Canal & Southern Caribbean Discovery - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 8 Get a Quote
Holland America, Nieuw Amsterdam
12Night Panama Canal Discovery Cruise Costa Rica Greater Antilles $1078 pp12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Nov 8 Get a Quote
Azamara Cruises, Azamara Quest
18 Nights Panama Canal Cruise from $3939 pp18 Night - Panama Canal Holiday Cruise : Miami, Cabo Rojo & San Diego - Starting in Miami, Florida, Cabo Rojo, Cartagena CO, Panama Canal (Cruising), Puntarenas, Puerto Quetzal, Puerto Vallarta, San Diego, San Francisco, California
2026 Sails: Dec 18 Get a Quote
Holland America, Zaandam
15 Nights Panama Canal Holiday Cruise from $1530 pp15 Night - Panama Canal Holiday - Starting in San Diego, California, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Dec 19 Get a Quote
Holland America, Zaandam
15 Nights Panama Canal Holiday Cruise from $1530 pp15 Night - Panama Canal Holiday - Starting in San Diego, California, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: Dec 19 Get a Quote
Holland America, Nieuw Amsterdam
19 Nights Panama Canal Holiday Cruise Amber Cove & Costa Rica $1836pp plus19 Night - Panama Canal Holiday : Amber Cove & Costa Rica - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Key West, Florida, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Dec 20 Get a Quote
Holland America, Nieuw Amsterdam
12Night Panama Canal Holiday Cruise Costa Rica &Greater Antilles $1394pp12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Dec 27
2027 Sails: Jan 17 Get a Quote
Holland America, Nieuw Amsterdam
21 Nights Panama Canal & Southern Caribbean Holiday Cruise $2147 pp plus21 Night - Panama Canal & Southern Caribbean Holiday - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Dec 27 Get a Quote
Panama Cruise Specials
