Panama Cruise Specials
We've gathered all of the Panama cruise specials ordered by sail date. Click on a special and select a sail date to get a single cruise quote from the cruise agency that posted that particular special. To search through all cruise itineraries (not just Panama cruises) to receive multiple custom cruise options to compare, please visit our Cruise Search page.
Crystal Cruises, Crystal Symphony
32 Nights Panama Canal Transit Cruise from $13960 pp plus OBC32 Night - The Americas & Caribbean - Starting in San Diego, Ensenada, Cabo San Lucas (Baja California Sur), Puerto Vallarta, Acajutla, Playa Flamingo, Puntarenas, Manta, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan, Marigot, St Martin, Roseau, Bridgetown, Castries, St Lucia, St Johns, Jost Van Dyke, British Virgin Islands, Samana, Grand Turk, New York
2026 Sails: Aug 24 Get a Quote
Crystal Cruises, Crystal Symphony
9 Nights Panama Canal & Caribbean Cruise from $4215 pp plus OBC9 Night - The Americas & Caribbean - Starting in Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Santo Domingo, Punta Cana, San Juan
2026 Sails: Sep 5 Get a Quote
Cunard Line, Queen Elizabeth
21 Nights Panama Canal Cruise from $1383 pp21 Night - Seattle to Miami - Starting in Seattle, WA, Los Angeles, CA, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Fuerte Amador (tours to Panama City), Panama, Transit the Panama Canal, Panama (Full Transit), Willemstad AN, Curacao, Oranjestad, Aruba, Miami, FL
2026 Sails: Sep 24 Get a Quote
Holland America, Nieuw Amsterdam
21 Nights Panama Canal Cruise from $2225 pp plus OBC21 Night - Panama Canal - Starting in Vancouver, BC, CA, San Francisco, California, San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 27 Get a Quote
Holland America, Nieuw Amsterdam
16 Nights Panama Canal Cruise from $1715 pp plus OBC16 Night - Panama Canal - Starting in San Diego, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Acajutla, El Salvador, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 2 Get a Quote
Holland America, Eurodam
21 Nights Panama Canal Cruise from $2104 pp plus OBC21 Night - Panama Canal - Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 3 Get a Quote
Holland America, Eurodam
21 Nights Panama Canal Cruise from $2104 pp plus OBC21 Night - Panama Canal - Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2026 Sails: Oct 3 Get a Quote
Holland America, Nieuw Amsterdam
12 Nights Panama Canal Discovery Cruise from $1164 pp plus OBC12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles - Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Ocho Rios, Jamaica, Fort Lauderdale, Florida
2026 Sails: Nov 8 Get a Quote
Celebrity Cruises, Celebrity Ascent
11 Nights Transcanal Cruise Special agency Rate Plus OBC $188911 Night - Panama Canal & Southern Caribbean - Starting in Fort Lauderdale, Florida, Cartagena CO, Panama Canal (Cruising), Colon, Panama, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Fort Lauderdale, Florida
2026 Sails: Nov 23
2027 Sails: Mar 8 Get a Quote
Crystal Cruises, Crystal Serenity
19 Nights Caribbean & Panama Canal Cruise from $9520 pp plus OBC19 Night - The Americas & Caribbean - Starting in Fort Lauderdale, Nassau (Paradise Island), Samana, San Juan, Jost Van Dyke, British Virgin Islands, Oranjestad, Aruba, Cartagena CO, Willemstad AN, Kralendijk, Oranjestad, Aruba, Santa Marta, Panama Canal Transit, Fuerte Amador (Panama City), Puntarenas
2026 Sails: Nov 23 Get a Quote
Panama Cruise Specials
