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Panama Cruise Departures

Cruises that depart from Central America: Panama

Cruises that visit Panama

Click on a cruise ship itinerary sailing from Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Related areas: Balboa : Colon : Flamenco Marina : Fuerte Amador : Panama City




Safari Voyager Cruises7 Night - Colombia & Panama—Coral, Jungles, Canal from Panama City to Cartagena
Starting in Panama City; with stops in Darien Jungle; Isla Taboga; Panama Canal; Guna Yala; Capurgana; Sapzurro; Cartagena
2020 Sails: Oct 3, Oct 17, More...
Silver Explorer Cruise Ship8 Night - E1201031008 - Colon to Guayaquil
Starting in Colon with stops in Panama Canal Transit, Darien Jungle, Bahia Solano, Utria National Park, Gorgona Island, Isla de la Plata, Machala, Guayaquil
2020 Sails: Oct 31, More...
Royal Clipper Cruise Ship14 Night - Panama Canal from Panama to Antigua
Starting in Balboa (Isla Flamenco), Panama; with stops in Panama Canal Transit; San Blas Islands, Panama; At sea; Cartagena de Indias, Colombia; Santa Marta, Colombia; At sea; Oranjestad, Aruba; Willemstad, Curacao; Kralendijk, Bonaire; At sea; St. George's, Grenada; Soufriere Bay, St. Lucia; Deshaies, Guadeloupe; St. John's, Antigua
2020 Sails: Nov 21, More...
Wind Star Cruise Tours11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour - Colon to San Jose
Cruise Ports: Departing from Colon, Panama with stops in; Panama Canal, Panama; Balboa / Fuerte Amador, Panama; Isla Parida, Panama; Puerto Jimenez (Gulfo Dulce), Costa Rica; Quepos, Cost Rica; Puerto Caldera, Costa Rica; Land Tour: Monteverde; Arenal; San Jose, Costa Rica
2020 Sails: Nov 28, Dec 12, Dec 26, 2021: Jan 9, Jan 23, Feb 6, More...
Safari Voyager Cruises10 Night - Costa Rica & Panama—Canal, Culture, Adventure from Panama City to San Jose
Starting in Panama City; with stops in Fort San Lorenzo; Panama Canal; Darien Jungle; Pearl Islands Archipelago; Gulf of Panama; Granito de Oro; Coiba National Park; Golfo Dulce; Osa Conservation Area; Curo National Wildlife Refuge; San Jose
2020 Sails: Dec 18, 2021: Jan 7, Jan 27, Feb 16, Mar 8, Mar 28, More...
S/C Panorama Cruise Ship7 Night - /21 - Crossing the Panama Canal: Panama to Costa Rica - Panorama
Starting in Colon 2000 Port with stops in Flamenco Marina, Playa Muerto, Coiba Islands, Golfito, Playa Biesanz, Drake Bay, Puerto Caldera
2020 Sails: Dec 19, 2021: Jan 2, More...
Le Champlain Cruises7 Night - Natural & Cultural History of Central America from Colón to Puerto Caldera
Starting in Colon; with stops in San Blas Islands; Playa Muerto, Darien National Park; Manuel Antonio National Park; Curú Wildlife Refuge; Puerto Caldera
2020 Sails: Dec 29, More...
Le Dumont-D'Urville Cruises7 Night - Tropical Rainforests & the Panama Canal from Colón to Puerto Caldera
Starting in Colón; with stops in San Blas Islands; Crossing the Panama Canal; Muerto, Darien National Park; Manuel Antonio National Park; Curu Wildlife Refuge; Tortuga Island; Puerto Caldera
2021 Sails: Jan 4, More...
Le Champlain Cruises9 Night - Between Panama and Martinique Cruise From Colon, Panama to Fort de France, Martinique
Starting in Colon, with stops in San Blas Islands, Cartagena, St George's, Mayreau, Soufriere , Fort de France
2021 Sails: Jan 12, More...
Wind Star Cruise Ship7 Night - Colon to Puerto Caldera-Wind Star-
Starting in Colon with stops in Panama Canal, Balboa / Fuerte Amador, Isla Parida, Puerto Jimenez, Quepos, Puerto Caldera
2021 Sails: Jan 23, More...


Panama Cruise Departures

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