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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Windstar, Star Pride
Star Pride7 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2027 Sails: Dec 6, Dec 20, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
Windstar Tours, Star Pride Tours
Star Pride Tours10 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera, Santa Elena (Monteverde), La Fortuna (Arenal), Costa Rica, Puerto Caldera, San Jose, Costa Rica
2027 Sails: Dec 6, 2028: Jan 3, Jan 17, Jan 31, Feb 14, More...
Norwegian Cruise Line, Norwegian Jewel
Norwegian Jewel11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2027 Sails: Dec 9, More...
Windstar Tours, Star Pride Tours
Star Pride Tours11 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in San Jose, Costa Rica, La Fortuna (Arenal), Costa Rica, Santa Elena (Monteverde), Puerto Caldera, San Jose, Costa Rica, Puerto Caldera, Golfo Dulce (Puerto Jimenez), Quepos, Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2027 Sails: Dec 9, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity11 Night - The Americas & Caribbean
Starting in Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Dec 11, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem10 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Falmouth, Jamaica, Great Stirrup Cay, Bahamas, Miami, Fl
2027 Sails: Dec 11, More...
MSC Cruises, MSC Poesia
MSC Poesia21 Night - Caribbean and Antilles
Starting in Miami, Florida, Ocho Rios, Jamaica, Cartagena CO, Colon, Panama, Puerto Limon, Costa Rica, Isla De Roatan, Honduras, Belize City, Belize, Miami, Florida, Oranjestad, Aruba, Willemstad AN, Curacao, Kralendijk, Bonaire, Cabo Rojo, Dominican Republic, Ocho Rios, Jamaica, Miami, Florida
2027 Sails: Dec 12, More...
Princess Cruises, Island Princess
Island Princess16 Night - Panama Canal - Ocean to Ocean Holiday
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit Historic Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Manzanillo, Mexico, Los Angeles, California
2027 Sails: Dec 13, More...
Windstar, Star Pride
Star Pride7 Night - Costa Rica & Panama Canal
Starting in Puerto Caldera, Golfo Dulce (Puerto Jimenez), Quepos, Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2027 Sails: Dec 13, More...
Holland America, Zaandam
Zaandam15 Night - Panama Canal Holiday
Starting in San Diego, California, Cabo San Lucas, Mexico, Puerto Vallarta, Mexico, Manzanillo, Mexico, Huatulco, Mexico, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Miami, Florida
2027 Sails: Dec 18, More...

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Panama Cruises