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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Cruises that depart from Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



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Star Breeze Cruises7 Night - Colon to Puerto Caldera - Star Breeze
Starting in Colon with stops in Panama Canal, Balboa / Fuerte Amador, Isla Parida, Golfo Dulce , Quepos, Puerto Caldera
2021 Sails: Aug 28, More...
MS Roald Amundsen Cruises14 Night - Caribbean Sea - Hidden Highlights and Sailing Through the Panama Canal (Itinerary 1) from Nassau to Panama City
Starting in Nassau, The Bahamas with stops in Inagua Islands, The Bahamas; Cockburn Town, Turks and Caicos; Port Antonio, Jamaica; Montego Bay, Jamaica; George Town, Cayman Islands; Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Sep 25, More...
MS Fram Cruises14 Night - Panama and Peru - Through the Panama Canal and Along the Andean Coast from Colon to Valparaiso
Starting in Colón, Panama with stops in Panama Canal; Manta, Ecuador; Puerto Bolivar / Machala; Salaverry, Peru; Callao / Lima, Peru; Paracas, Peru; Matarani, Peru; Arica, Chile; Valparaíso, Chile
2021 Sails: Oct 1, More...
MS Roald Amundsen Cruises7 Night - Hidden Highlights of the Caribbean from George Town to Panama City
Starting in George Town, Cayman Islands with stops in Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 2, More...
MS Fridtjof Nansen Cruises14 Night - Caribbean Sea - Hidden Highlights and Sailing Through the Panama Canal (Itinerary 2) from Nassau to Panama City
Starting in Nassau, The Bahamas with stops in Inagua Islands, The Bahamas; Cockburn Town, Turks and Caicos; Port Antonio, Jamaica; Montego Bay, Jamaica; George Town, Cayman Islands; Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 5, More...
MS Fridtjof Nansen Cruises7 Night - Hidden Highlights of the Caribbean from George Town to Panama City
Starting in George Town, Cayman Islands with stops in Isla de Providencia, Colombia; Corn Island, Nicaragua; Bocas del Toro, Panama; San Blas Island, Panama; Panama Canal, Panama; Panama City, Panama
2021 Sails: Oct 12, More...
Celebrity Millennium Cruise Ship15 Night - Panama Canal Eastbound Cruise from San Diego, California - Onboard Celebrity Millennium
Starting in San Diego with stops in Cabo San Lucas, Puerto Vallarta, Puerto Quetzal, Puntarenas, Panama Canal, Colon, Cartagena, Fort Lauderdale
2021 Sails: Oct 27, More...
HAL Eurodam Cruise Ship25 Night - Spanish Farewell & Panama Canal Sunfarer
Starting in Barcelona with stops in Cartagena, Malaga, Cadiz, Lisbon, Funchal, Ponta Delgada, Fort Lauderdale, Half Moon Cay, Oranjestad, Willemstad, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Puerto Limon
2021 Sails: Oct 30, More...
Carnival Pride Cruise Ship14 Night - Panama Canal from Baltimore, MD
Starting in Baltimore with stops in Grand Turk, Aruba, Curacao, Panama Canal Partial Transit, Mahogany Bay, Belize, Cozumel, Tampa
2021 Sails: Oct 31, More...
Royal Clipper Cruise Ship14 Night - Barbados to Panama
Starting in Bridgetown, Barbados; with stops in Soufriere Bay, St. Lucia; Tobago Cays, Grenadines; St. Georges, Grenada; Kralendijk, Bonaire; Willemstad, Curacao; Oranjestad, Aruba; Cartagena de Indias, Colombia; Islas de San Bernardo, Colombia; San Blas Islands, Panama; Isla Mamey (Beach); Portobelo, Panama; Panama Canal Transit; Balboa (Isla Flamenco), Panama
2021 Sails: Nov 6, 2022: Nov 5, More...


Panama Canal Cruises

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