Panama Canal Cruises
Cruises that visit Central America: Panama: Panama Canal
16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 16, More...
18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 23, More...14 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Apr 23, More...
10 Night - Canal & Coral Isles
Starting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
15 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...18 Night - Panama Canal - Miami
Starting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
10 Night - Panama Canal Westward Cruise
Starting in Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 25, More...
14 Night - Grand World Voyage
Starting in San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: May 3, More...
115 Night - World Cruise - Roundtrip Auckland
Starting in Auckland, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand
2026 Sails: May 6, More...117 Night - World Cruise - Sydney to Brisbane
Starting in Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Sydney AU, Brisbane, Australia
2026 Sails: May 10, More...
Cruises that visit Central America: Panama: Panama Canal
Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.
16 Night - Panama Canal - Ocean to OceanStarting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 16, More...
18 Night - Msc Grand VoyagesStarting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2026 Sails: Apr 23, More...
14 Night - Msc Grand VoyagesStarting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Puntarenas (San Jose), Costa Rica, Cabo San Lucas, Mexico, San Diego, Los Angeles
2026 Sails: Apr 23, More...
10 Night - Canal & Coral IslesStarting in Panama City, Panama Canal Daylight Transit, Cartagena CO, Puerto Limon, Roatan, Costa Maya, Mexico, Cozumel, Mexico, Miami
2026 Sails: Apr 24, More...
15 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca
2026 Sails: Apr 25, More...
18 Night - Panama Canal - MiamiStarting in Miami, Fl, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, Los Angeles, Ca, Seattle, Wa
2026 Sails: Apr 25, More...
10 Night - Panama Canal Westward CruiseStarting in Colon, Panama, Panama Canal (Cruising), Puntarenas, Costa Rica, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Apr 25, More...
14 Night - Grand World VoyageStarting in San Diego, California, Manzanillo, Mexico, Puerto Chiapas, Mexico, Acajutla, El Salvador, Fuerte Amador, Panama, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Cartagena CO, Fort Lauderdale, Florida
2026 Sails: May 3, More...
115 Night - World Cruise - Roundtrip AucklandStarting in Auckland, New Zealand, Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand
2026 Sails: May 6, More...
117 Night - World Cruise - Sydney to BrisbaneStarting in Sydney AU, Melbourne, Australia, Adelaide, Australia, Perth (Fremantle), Australia, Port Louis, Mauritius, Cape Town, South Africa, Walvis Bay, Namibia, Mindelo, Cape Verde Islands, Gran Canaria (Las Palmas), Canary Islands, Casablanca, Morocco (for Marrakesh), La Coruna, Spain (for Santiago de Compostela), Le Havre (for Paris / Normandy), France, Zeebrugge (for Brussels / Bruges), Belgium, Gdansk (Gdynia), Poland, Visby, Sweden, Helsinki, Finland, Tallinn, Estonia, Stockholm, Sweden, Copenhagen, Denmark, Amsterdam (IJmuiden), Netherlands, Dover UK (for London), England, Shetland Islands (Lerwick), Scotland, Reykjavik, Iceland, Grundarfjordur, Iceland, Isafjordur, Iceland, St Johns NF, Newfoundland, Corner Brook, Canada, Quebec City, Canada, Saguenay, Canada, Charlottetown, Canada, Sydney CA, Halifax, Canada, New York City (Manhattan or Brooklyn), New York, Miami, Florida, Cartagena CO, Panama Canal Full Transit New Locks, Manta, Ecuador, Lima (Callao), Peru, Pisco (General San Martin), Peru, Easter Island, Chile, Pitcairn Island (Scenic Cruising), Pitcairn Islands, Tahiti (Papeete), French Polynesia, Moorea, French Polynesia, Cross International Date Line, Auckland, New Zealand, Sydney AU, Brisbane, Australia
2026 Sails: May 10, More...
