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Panama Canal Cruises

Cruises that visit Central America: Panama: Panama Canal

Click on a cruise ship itinerary that visits Panama Canal (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama Canal), please visit: Cruise Search or try our Virtual Cruise Advisor™.



NCL Norwegian Jewel Cruise Ship11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2025 Sails: Dec 1, Dec 12, 2026: Jan 19, Mar 4, More...
Seabourn Encore Cruises47 Night - Panama Canal Passage & Pacific Crossing
Starting in Miami, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador (Panama City), Panama, Puntarenas (Puerto Caldera), Costa Rica, Puerto Chiapas, Mexico, Puerto Vallarta, Mexico, Honolulu, Hawaii, Nawiliwili, Kauai, Hawaii, Cross International Dateline, Tokyo, Japan, Osaka, Japan, Kochi, Japan, Keelung (Taipei), Taiwan, Hong Kong, China
2025 Sails: Dec 2, More...
Seabourn Encore Cruises27 Night - Caribbean, Panama Canal Passage & Hawaii
Starting in Miami, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador (Panama City), Panama, Puntarenas (Puerto Caldera), Costa Rica, Puerto Chiapas, Mexico, Puerto Vallarta, Mexico, Honolulu, Hawaii
2025 Sails: Dec 2, More...
Seabourn Encore Cruises10 Night - Caribbean & Panama Canal Passage
Starting in Miami, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Fuerte Amador (Panama City), Panama
2025 Sails: Dec 2, More...
Oceania Vista Cruises17 Night - A Tale of Two Seas
Starting in Miami, Kingston (Port Royal), Santa Marta, Cartagena CO, Panama Canal Daylight Transit, Puntarenas, Acajutla, Puerto Quetzal, Huatulco, Puerto Vallarta, Los Angeles
2025 Sails: Dec 3, More...
Wind Spirit Cruise Ship7 Night - Costa Rica & Panama Canal
Starting in Puerto Caldera, Quepos, Golfo Dulce (Puerto Jimenez), Isla Partida, Balboa / Fuerte Amador, Panama Canal, Colon
2025 Sails: Dec 6, More...
HAL Rotterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 7, 2026: Feb 8, Mar 1, More...
HAL Rotterdam Cruise Ship12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2025 Sails: Dec 7, 2026: Feb 8, Mar 1, More...
National Geographic Quest Cruises7 Night - The Panama Canal, Pearl Islands and Darien Jungle
Starting in Panama City, Panama / Colon / Embark Ship, Portobelo / Panama Canal Transit, Gatun Lake / Panama Canal Transit, Punta Patino Nature Reserve, Playa Muerto, Darien National Park, Pearl Islands, Balboa / Disembark Ship / Panama City, Panama
2025 Sails: Dec 7, 2026: Jan 9, Dec 6, 2028: Mar 9, More...
Island Princess Cruise Ship16 Night - Panama Canal - Ocean to Ocean
Starting in San Francisco, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Cartagena CO, Fort Lauderdale, Florida
2025 Sails: Dec 7, More...


Panama Canal Cruises