Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Crystal Cruises, Crystal Symphony

27 Night - The Americas & Caribbean
Starting in Fort Lauderdale, Cozumel, Quintana Roo, Belize City, Santo Tomas, Roatan Island, Puerto Limon, Colon, Cartagena CO, Oranjestad, Aruba, Willemstad AN, Kralendijk, Pointe-a-Pitre, French West Indies, Marigot, St Martin, San Juan, St Kitts (Basseterre), Fort-de-France, Roseau, St Johns, Gustavia, St Barthelemy, Road Town, Fort Lauderdale
2027 Sails: Nov 22, More...

Windstar, Star Pride

21 Night - Star Collector : Windward Islands, Spanish Cities & Costa Rica
Starting in San Juan, St Georges, Bequia, Mayreau, Les Saintes, Marigot, St Martin, San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2027 Sails: Nov 22, More...

Windstar, Star Pride

14 Night - Star Collector : Caribbean Islands & Colombian Coast Discovery
Starting in San Juan, St Georges, Bequia, Mayreau, Les Saintes, Marigot, St Martin, San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon
2027 Sails: Nov 22, More...

Virgin Voyages, Brilliant Lady

17 Night - Panama Canal : Los Angeles to Miami
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama City, Panama, Panama Canal (Cruising), Panama, Cartagena CO, Miami, Florida
2027 Sails: Nov 27, More...

Crystal Cruises, Crystal Serenity

12 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Nov 29, More...

Crystal Cruises, Crystal Serenity

23 Night - South America
Starting in Valparaiso, Coquimbo, Iquique, Pisco, Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City), Panama Canal Transit, Puerto Limon, Roatan Island, Santo Tomas, Belize City, Cozumel, Quintana Roo, Progreso (Merida), Fort Lauderdale
2027 Sails: Nov 29, More...

Viking Ocean, Viking Mars

10 Night - Classic Panama Canal Passage
Starting in Panama City (Fuerte Amador), Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Merida (Progreso), Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Nov 29, 2028: Jan 16, More...

Windstar, Star Pride

7 Night - The Spanish Main : Rise of the New World
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon
2027 Sails: Nov 29, More...

Windstar, Star Pride

14 Night - Star Collector : Coffee, Canal & Callaloo : Central America, Colombia & the Caribbean
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas, Panama, Colon, Panama Canal, Balboa / Fuerte Amador, Isla Partida, Golfo Dulce (Puerto Jimenez), Quepos, Puerto Caldera
2027 Sails: Nov 29, More...

Explora Journeys, EXPLORA II

10 Night - A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities
Starting in Miami, Port Antonio, Colon, Bocas del Toro, Puerto Limon, San Andres Island, Miami
2027 Sails: Dec 2, More...

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