Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

AmaWaterways Tours, AmaMelodia Tours

15 Night - Wonders of Colombia with in Medellin, in Cartagena Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City, Barranquilla, Panama City
2027 Sails: Jun 11, More...

AmaWaterways Tours, AmaMelodia Tours

10 Night - Wonders of Colombia with in Panama City Post Cruise
Starting in Cartagena CO, Colombia, Palenque, Calamar, Santa Barbara de Pinto, Mompox, Magangue, Sitionuevo, Barranquilla, Panama City, Barranquilla, Panama City
2027 Sails: Jun 16, More...

Crystal Cruises, Crystal Serenity

32 Night - The Americas & Caribbean
Starting in Vancouver, Victoria CA, Canada, Astoria, San Francisco, Santa Catalina Island, San Diego, Puerto Vallarta, Manzanillo, Zihuatanejo, Acajutla, San Juan del Sur, Puntarenas, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Port Antonio, Montego Bay, George Town (Grand Cayman), Miami, Port Canaveral, Norfolk, New York
2027 Sails: Aug 2, More...

Crystal Cruises, Crystal Serenity

25 Night - The Americas & Caribbean
Starting in San Diego, Puerto Vallarta, Manzanillo, Zihuatanejo, Acajutla, San Juan del Sur, Puntarenas, Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Port Antonio, Montego Bay, George Town (Grand Cayman), Miami, Port Canaveral, Norfolk, New York
2027 Sails: Aug 9, More...

Crystal Cruises, Crystal Serenity

14 Night - The Americas & Caribbean
Starting in Fuerte Amador (Panama City), Panama Canal Transit, Cartagena CO, Port Antonio, Montego Bay, George Town (Grand Cayman), Miami, Port Canaveral, Norfolk, New York
2027 Sails: Aug 20, More...

Celebrity Cruises, Celebrity Summit

18 Night - Panama Canal Eastbound Cruise
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, Grand Turk, Turks and Caicos, Boston, Massachusetts
2027 Sails: Sep 18, More...

Princess Cruises, Coral Princess

23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 22, More...

Carnival Cruise Lines, Carnival Spirit

16 Night - Journeys - Panama Canal
Starting in Seattle, Wa, Cabo San Lucas, Mexico, Puntarenas, Costa Rica, Panama Canal Transit, Cartagena CO, Galveston, Tx
2027 Sails: Sep 25, More...

Carnival Cruise Lines, Carnival Valor

14 Night - Journeys - Caribbean & Panama
Starting in Mobile, Al, Ocho Rios, Jamaica, Aruba, Curacao, Cartagena CO, Colon (Panama Canal), Panama, Limon, Costa Rica, Cozumel, Mexico, Mobile, Al
2027 Sails: Sep 26, More...

MSC Cruises, MSC Poesia

19 Night - Msc Grand Voyages
Starting in Seattle, Washington, Los Angeles, San Diego, Cabo San Lucas, Mexico, Huatulco, Mexico, Cruising Panama Canal, Colon, Panama, Cartagena CO, Miami, Florida
2027 Sails: Sep 27, More...

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