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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Holandes Cays : Isla del Rey : Isla Iguana : Lemon Cay : Mogo Mogo Island : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Viking Ocean, Viking Mars
Viking Mars10 Night - Classic Panama Canal Passage
Starting in Panama City (Fuerte Amador), Scenic Sailing Panama Canal, Colon, Puerto Limon, Sail the Caribbean Sea, Belize City, Cozumel, Mexico, Merida (Progreso), Sail the Caribbean Sea, Fort Lauderdale, Florida
2027 Sails: Nov 29, 2028: Nov 4, Dec 8, Dec 28, More...
Windstar, Star Pride
Star Pride7 Night - The Spanish Main : Rise of the New World
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon
2027 Sails: Nov 29, More...
Windstar, Star Pride
Star Pride14 Night - Star Collector : Coffee, Canal & Callaloo : Central America, Columbia & the Caribbean
Starting in San Juan, Isla Catalina, Santo Domingo, Cartagena CO, San Blas Islands, Panama, Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Puerto Caldera, San Jose
2027 Sails: Nov 29, More...
Norwegian Cruise Line, Norwegian Gem
Norwegian Gem11 Night - Panama Canal - Miami
Starting in Miami, Fl, Great Stirrup Cay, Bahamas, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Fl
2027 Sails: Nov 30, More...
Explora Journeys, EXPLORA II
EXPLORA II10 Night - A Journey Through Caribbean Havens & the Tropical Gems of Seaside Cities
Starting in Miami, Port Antonio, Colon, Bocas del Toro, Puerto Limon, San Andres Island, Miami
2027 Sails: Dec 2, More...
PONANT, Le Bougainville
Le Bougainville10 Night - Secrets of Central America
Starting in Colon, Fort San Lorenzo (Colon), San Blas Islands, Crossing the Panama Canal, Pearls Islands, Pacheca Island, Playa Muerto, Darien National Park, Coiba Island, Rio Esquinas, Drake Bay, Curu Wildlife Refuge, Puntarenas
2027 Sails: Dec 2, More...
Princess Cruises, Caribbean Princess
Caribbean Princess12 Night - Southern Caribbean with Panama
Starting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, Aruba, Cartagena CO, Colon, Panama, Limon, Costa Rica, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida
2027 Sails: Dec 2, More...
Carnival Cruise Lines, Carnival Spirit
Carnival Spirit8 Night - Caribbean & Panama
Starting in Tampa, Fl, Limon, Costa Rica, Colon (Panama Canal), Panama, Grand Cayman, Cayman Islands, Tampa, Fl
2027 Sails: Dec 4, Dec 18, 2028: Feb 26, Mar 25, More...
Crystal Cruises, Crystal Serenity
Crystal Serenity6 Night - South America
Starting in Lima (Callao), Salaverry, Guayaquil, Fuerte Amador (Panama City)
2027 Sails: Dec 5, More...
Royal Caribbean, Grandeur of the Seas
Grandeur of the Seas7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2027 Sails: Dec 5, Dec 12, Dec 26, 2028: Jan 30, Feb 6, Feb 13, Mar 12, Mar 26, More...

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Panama Cruises