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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Princess Cruises, Coral Princess
Coral Princess18 Night - Panama Canal - Ocean to Ocean
Starting in Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, New York City (Manhattan or Brooklyn), New York
2027 Sails: Sep 27, More...
Norwegian Line Tours, Norwegian Joy Tours
Norwegian Joy Tours19 Night - Pre Los Angeles Cruisetour
Starting in At Hotel, Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Fl
2027 Sails: Sep 28, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy17 Night - Panama Canal - Miami
Starting in Los Angeles, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puerto Caldera / Puntarenas, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, Ocho Rios, Jamaica, George Town, Cayman Islands, Miami, Fl
2027 Sails: Sep 30, More...
Holland America, Eurodam
Eurodam21 Night - Panama Canal
Starting in Seattle, Washington, Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 2, More...
Holland America, Eurodam
Eurodam20 Night - Panama Canal
Starting in Vancouver, BC, CA, Santa Barbara, California, San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 3, More...
Princess Cruises, Star Princess
Star Princess23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, Seattle, Washington, San Francisco, California, Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit New Locks, Aruba, Port Canaveral (Orlando), Florida
2027 Sails: Oct 3, More...
Princess Cruises, Island Princess
Island Princess23 Night - Panama Canal & Pacific Coast
Starting in Vancouver, Canada, San Francisco, California, Santa Barbara, California, San Diego, California, Los Angeles, California, Puerto Vallarta, Mexico, Huatulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Fuerte Amador, Panama (for Panama City), Panama Canal Full Transit Historic Locks, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 6, More...
Holland America, Eurodam
Eurodam16 Night - Panama Canal
Starting in San Diego, California, Cabo San Lucas, Mexico, Acapulco, Guerrero, Mexico, Huatulco, Mexico, Puerto Chiapas, Mexico, Puerto Quetzal, Guatemala, Puntarenas (Puerto Caldera), Costa Rica, Enter Panama Canal Balboa, Cruising Panama Canal, Exit Panama Canal Cristobal, Oranjestad, Aruba, Fort Lauderdale, Florida
2027 Sails: Oct 7, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas15 Night - Panama Canal Eastward Cruise
Starting in San Diego, California, Puerto Vallarta, Mexico, Puerto Quetzal, Guatemala, Puntarenas, Costa Rica, Panama Canal (Cruising), Cartagena CO, George Town, Grand Cayman, Tampa, Florida
2027 Sails: Oct 7, More...
Oceania Cruises, Oceania Vista
Oceania Vista32 Night - Around the Americas
Starting in Montreal, Quebec City, Saguenay, Sept-Iles, Havre, Saint Pierre, Corner Brook, Sydney CA, Halifax, Royal Naval Dockyard, Nassau, Miami, George Town, Cartagena CO, Panama Canal Daylight Transit, Puntarenas, Puerto Quetzal, Acapulco, Puerto Vallarta, Mazatlan, Cabo San Lucas, Los Angeles
2027 Sails: Oct 10, More...

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Panama Cruises