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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Balboa : Barro Colorado Island : Bocas del Toro : Cayos Limones : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Isla Iguana : Lemon Cay : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Holland America, Eurodam
Eurodam21 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California, San Francisco, California, Vancouver, BC, CA, Seattle, Washington
2027 Sails: Apr 3, More...
Holland America, Eurodam
Eurodam20 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California, San Francisco, California, Vancouver, BC, CA
2027 Sails: Apr 3, More...
Holland America, Eurodam
Eurodam14 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Puerto Quetzal, Guatemala, Huatulco, Mexico, Puerto Vallarta, Mexico, San Diego, California
2027 Sails: Apr 3, More...
Princess Cruises, Star Princess
Star Princess16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Mazatlan, Mexico, Cabo San Lucas, Mexico, Los Angeles, California
2027 Sails: Apr 3, More...
Scenic Luxury, Scenic Eclipse II
Scenic Eclipse II11 Night - Pristine Islands of the Caribbean & the Panama Canal
Starting in Panama City, Panama, Panama City / Panama Canal Transit, San Blas Islands, Lemon Cay, Panama, Cartagena CO, Cabo de La Vela, Colombia, Willemstad AN, Curacao, Tobago Cays, Grenadines, Mayreau, Grenadines, Soufriere, St Lucia, Bridgetown, Barbados
2027 Sails: Apr 3, More...
Carnival Cruise Lines, Carnival Legend
Carnival Legend16 Night - Journeys - Panama Canal
Starting in Tampa, Fl, Santa Marta, Colombia, Cartagena CO, Panama Canal Transit, Acapulco, Mexico, Cabo San Lucas, Mexico, Seattle, Wa
2027 Sails: Apr 4, More...
Princess Cruises, Crown Princess
Crown Princess16 Night - Panama Canal - Ocean to Ocean
Starting in Fort Lauderdale, Florida, Aruba, Panama Canal Full Transit New Locks, Fuerte Amador, Panama (for Panama City), Puntarenas, Costa Rica, Puerto Chiapas, Mexico, Huatulco, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2027 Sails: Apr 4, More...
Explora Journeys, EXPLORA III
EXPLORA III17 Night - A Grand Journey Through Balmy Shores & Enchanting Nature to Panama's Wonders
Starting in San Juan, Gustavia, Little Bay, Basseterre, Key West, Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 5, More...
MSC Cruises, MSC Magnifica
MSC Magnifica30 Night - Msc World Cruise
Starting in Los Angeles, Cabo San Lucas, Mexico, Puntarenas (San Jose), Costa Rica, Cruising Panama Canal, Ocho Rios, Jamaica, Road Town (Tortola), British Virgin Islands, Philipsburg, St Maarten, Las Palmas de Gran Canaria (Canary Islands), Spain, Palma De Mallorca (Balearic Islands), Spain, Naples (Pompeii), Italy, Civitavecchia (Rome), Italy, Genoa (Portofino), Italy, Marseille (Provence), France
2027 Sails: Apr 7, More...
MSC Cruises, MSC Poesia
MSC Poesia18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2027 Sails: Apr 8, More...

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Panama Cruises