Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Lindblad Expeditions, Greg Mortimer

12 Night - Panama and Costa Rica's Pacific Coast : a Central America Odyssey
Starting in San Jose, Costa Rica / Puerto Caldera / Embark Ship, Santa Rosa National Park / Guanacaste Conservation Area, Rincon de la Vieja National Park / Hacienda Guachipelin, Curu Wildlife Refuge / Isla Tortuga, Osa Conservation Area, Osa Peninsula, Golfo Dulce, Coiba National Park, Panama, Isla Iguana Wildlife Refuge / Azuero Peninsula, Pearl Islands, Darien National Park, Panama City / Disembark Ship
2027 Sails: Apr 8, More...

MSC Cruises, MSC Poesia

18 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington
2027 Sails: Apr 8, More...

MSC Cruises, MSC Poesia

25 Night - Msc Grand Voyages
Starting in Miami, Florida, Cartagena CO, Colon, Panama, Cruising Panama Canal, Huatulco, Mexico, Cabo San Lucas, Mexico, San Diego, Los Angeles, Seattle, Washington, Ketchikan, Alaska, Icy Strait Point, Alaska, Cruising Tracy Arm Fjord, Alaska, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington
2027 Sails: Apr 8, More...

PONANT, Le Bellot

10 Night - Panama, Colombia & Caribbean Islands
Starting in Colon, San Blas Islands, Cartagena, Santa Marta, Bonaire, Mayreau Island, Pigeon Island Beach, Soufriere, Les Saintes, Fort-de-France
2027 Sails: Apr 8, More...

Norwegian Cruise Line, Norwegian Bliss

19 Night - Repo - Panama Canal
Starting in New York City, Ny, Puerto Plata, Dominican Republic, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca
2027 Sails: Apr 9, More...

Norwegian Cruise Line, Norwegian Bliss

22 Night - Repo - Panama Canal
Starting in New York City, Ny, Puerto Plata, Dominican Republic, Cartagena CO, Colon, Panama, Transit Panama Canal / At Sea, Puerto Caldera / Puntarenas, Costa Rica, Puerto Quetzal, Guatemala, Acapulco, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Francisco, Ca, Victoria CA, Canada, Seattle, Wa
2027 Sails: Apr 9, More...

Holland America, Nieuw Amsterdam

21 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Acapulco, Guerrero, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California, Victoria CA, Canada, Vancouver, BC, CA
2027 Sails: Apr 11, More...

Holland America, Nieuw Amsterdam

17 Night - Panama Canal
Starting in Fort Lauderdale, Florida, Oranjestad, Aruba, Enter Panama Canal Cristobal, Cruising Panama Canal, Exit Panama Canal Balboa, Puntarenas (Puerto Caldera), Costa Rica, Acajutla, El Salvador, Puerto Quetzal, Guatemala, Acapulco, Guerrero, Mexico, Puerto Vallarta, Mexico, Cabo San Lucas, Mexico, San Diego, California
2027 Sails: Apr 11, More...

Royal Caribbean, Grandeur of the Seas

7 Night - Southern Caribbean Cruise
Starting in Cartagena CO, Oranjestad, Aruba, Kralendijk, Bonaire, Willemstad AN, Curacao, Colon, Panama, Cartagena CO
2027 Sails: Apr 11, More...

Explora Journeys, EXPLORA III

10 Night - A Journey Through Enchanting Nature & the Marvels of the Panama Canal
Starting in Miami, Ocho Rios, Jamaica, Willemstad AN, Oranjestad, Santa Marta, Cartagena CO, Crossing the Panama Canal, Panama City (Amador)
2027 Sails: Apr 12, More...

<= Back

More =>