Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Costa Cruise Lines, Costa Deliziosa

91 Night - Round World from Civitavecchia (Rome)
Starting in Civitavecchia (Rome), Savona, Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU, Newcastle UK, New South Wales, Cairns, Rabaul, Tokyo, Kobe (Kyoto), Nagasaki, Busan, Keelung (Taipei), Hong Kong
2026 Sails: Nov 24, More...

Windstar, Wind Star

11 Night - Colombian & Southern Caribbean Coastlines
Starting in Bridgetown, Barbados, Bequia, St Georges, Grenada, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Cartagena CO, San Blas Islands, Panama, Colon
2026 Sails: Nov 24, More...

AmaWaterways Tours, AmaMagdalena Tours

13 Night - Magic of Colombia with in Medellin Pre Cruise and in Panama City Post Cruise
Starting in Medellin, Barranquilla, Medellin, Sitionuevo, Magangue, Mompox, Santa Barbara de Pinto, Calamar, Mahates, Cartagena CO, Colombia, Panama City
2026 Sails: Nov 25, Dec 9, Dec 23, More...

Costa Cruise Lines, Costa Deliziosa

65 Night - Round World from Savona
Starting in Savona, Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU
2026 Sails: Nov 25, More...

Costa Cruise Lines, Costa Deliziosa

39 Night - Round World from Savona
Starting in Savona, Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco
2026 Sails: Nov 25, More...

Costa Cruise Lines, Costa Deliziosa

138 Night - Round World from Savona
Starting in Savona, Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU, Newcastle UK, New South Wales, Cairns, Rabaul, Tokyo, Kobe (Kyoto), Nagasaki, Busan, Keelung (Taipei), Hong Kong, Nha Trang, Phu My (Ho Chi Minh City), Koh Samui, Singapore, Port Kelang (Kuala Lumpur), Penang, Colombo, Male, Port Louis, Durban, Port Elizabeth ZA, Cape Town, Walvis Bay, Mindelo (Sao Vicente), Las Palmas (Gran Canaria), Barcelona, Marseille, Savona
2026 Sails: Nov 25, More...

Costa Cruise Lines, Costa Deliziosa

90 Night - Round World from Savona
Starting in Savona, Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU, Newcastle UK, New South Wales, Cairns, Rabaul, Tokyo, Kobe (Kyoto), Nagasaki, Busan, Keelung (Taipei), Hong Kong
2026 Sails: Nov 25, More...

Costa Cruise Lines, Costa Deliziosa

38 Night - Round World from Marseille
Starting in Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco
2026 Sails: Nov 26, More...

Costa Cruise Lines, Costa Deliziosa

64 Night - Round World from Marseille
Starting in Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU
2026 Sails: Nov 26, More...

Costa Cruise Lines, Costa Deliziosa

136 Night - Round World from Marseille
Starting in Marseille, Barcelona, Lisbon, Ponta Delgada (Azores), Praia da Vitoria (Azores), New York, Port Everglades, Half Moon Cay, Panama City, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, San Diego, Los Angeles, San Francisco, Honolulu, Hilo, Papeete (Tahiti), Suva, Lifou (Loyalty Islands), Noumea, Sydney AU, Newcastle UK, New South Wales, Cairns, Rabaul, Tokyo, Kobe (Kyoto), Nagasaki, Busan, Keelung (Taipei), Hong Kong, Nha Trang, Phu My (Ho Chi Minh City), Koh Samui, Singapore, Port Kelang (Kuala Lumpur), Penang, Colombo, Male, Port Louis, Durban, Port Elizabeth ZA, Cape Town, Walvis Bay, Mindelo (Sao Vicente), Las Palmas (Gran Canaria), Barcelona, Marseille
2026 Sails: Nov 26, More...

<= Back

More =>