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Panama Cruises

Cruises that visit Central America: Panama

Cruises that depart from Panama

See all River Cruises that visit Panama

Click on a cruise ship itinerary that visits Panama (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Panama), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Azuero Peninsula : Balboa : Barro Colorado Island : Bocas del Toro : Cebaco Island : Chiriqui Lagoon : Coiba Island : Colon : Cristobal : Darien : Flamenco Island : Fort San Lorenzo : Fuerte Amador : Gatun : Gulf of Panama : Guna Yala : Holandes Cays : Isla del Rey : Isla Iguana : Lemon Cay : Mogo Mogo Island : Pacheca Island : Panama Canal : Panama City : Parida Island : Pearl Islands : Playa Muerto : Portobelo : Punta Patino : San Blas Islands : San Jose Island

Panama
Cruise Specials

Windstar, Wind Star
Wind Star8 Night - Costa Rica & Panama Canal
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Punta Leona, Puerto Caldera, San Jose
2027 Sails: Jan 31, More...
Windstar, Wind Star
Wind Star29 Night - Star Collector : Panama Canal Ocean Crossing to Tahitian Dreams
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Punta Leona, Puerto Caldera, San Jose, Papeete, Tahiti
2027 Sails: Jan 31, More...
Windstar, Wind Star
Wind Star36 Night - Star Collector : Pacific Horizons from Panama to Tahiti
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Punta Leona, Puerto Caldera, San Jose, Papeete, Tahiti, Morning Sailing French Polynesia, Raiatea, Motu Mahaea, Near Tahaa, Bora Bora, Huahine, Moorea, Papeete, Tahiti
2027 Sails: Jan 31, More...
Windstar Tours, Wind Star Tours
Wind Star Tours12 Night - Monteverde Cloud Forest & Arenal Volcano Cruise Tour
Starting in Colon, Panama Canal Transit, Fuerte Amador, Panama City, Isla Partida, Puerto Jimenez, Golfo Dulce, Quepos, Manuel Antonio National Park, Punta Leona, Puerto Caldera, San Jose, Santa Elena (Monteverde), Monteverde Hotel, La Fortuna (Arenal), Arenal Hotel, La Fortuna (Arenal), Arenal Hotel, San Jose, Costa Rica Marriott Hotel Hacienda Belen or Similar, Juan Santamaria International
2027 Sails: Jan 31, More...
Norwegian Cruise Line, Norwegian Sun
Norwegian Sun11 Night - Panama Canal - Miami
Starting in Miami, Fl, George Town, Cayman Islands, Cartagena CO, Panama Canal Gatun Lake, Panama, Colon, Panama, Puerto Limon, Costa Rica, Harvest Caye, Belize, Cozumel, Mexico, Miami, Fl
2027 Sails: Feb 6, More...
Holland America, Nieuw Amsterdam
Nieuw Amsterdam21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Oranjestad, Aruba, Cartagena CO, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2027 Sails: Feb 7, More...
Sea Cloud Spirit8 Night - Cruise from Willemstad to Colon
Starting in Willemstad AN, Curacao, Kralendijk, Oranjestad, Aruba, Cartagena CO, Colombia, San Blas Islands, Colon
2027 Sails: Feb 9, More...
Windstar, Star Legend
Star Legend13 Night - Star Collector : Latin America Explorer
Starting in Puerto Caldera, San Jose, Playa Flamingo, Punta Leona, Quepos, Manuel Antonio National Park, Puerto Jimenez, Golfo Dulce, Isla Partida, Fuerte Amador, Panama City, Panama Canal Transit, Bocas del Toro, San Blas Islands, Panama, Cartagena CO, Oranjestad, Aruba
2027 Sails: Feb 9, More...
Norwegian Line Tours, Norwegian Star Tours
Norwegian Star Tours18 Night - San Diego City Highlights Cruisetour Package
Starting in At Hotel, San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 11, More...
Norwegian Cruise Line, Norwegian Star
Norwegian Star16 Night - Repo - Panama Canal
Starting in San Diego, Ca, Cabo San Lucas, Mexico, Acapulco, Mexico, Puerto Quetzal, Guatemala, Puntarenas / Puerto Caldera, Costa Rica, Panama City, Panama, Transit Panama Canal / At Sea, Cartagena CO, George Town, Cayman Islands, Miami, Fl
2027 Sails: Feb 13, More...

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Panama Cruises