United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Tours, Island Princess Tours

10 Night - On Your Own - Tour Bbx
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 31, More...

Princess Tours, Island Princess Tours

10 Night - Denali Explorer - Tour Bb3
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 31, More...

Princess Tours, Island Princess Tours

10 Night - Denali Explorer - Tour Ab3
Starting in Anchorage, Mount Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: May 31, More...

Royal Caribbean, Star of the Seas

7 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Philipsburg, St Maarten, Orlando (Port Canaveral), Fl
2026 Sails: May 31, Jul 12, Aug 2, Aug 23, Sep 13, Oct 4, Oct 25, More...

Royal Caribbean, Symphony of the Seas

7 Night - Western Caribbean Cruise
Starting in Galveston, Texas, Roatan, Honduras, Puerto Costa Maya, Mexico, Cozumel, Mexico, Galveston, Texas
2026 Sails: May 31, Jun 14, Jun 21, Oct 18, Oct 25, Nov 1, Nov 15, Dec 13, Dec 27, 2027: Jan 24, Feb 21, Mar 7, Mar 21, More...

Silversea, Silver Nova

14 Night - Miami to Lisbon
Starting in Miami, Fl, Praia da Vitoria, Azores, Ponta Delgada (Sao Miguel Island), Funchal, Madeira, Lisbon
2026 Sails: May 31, More...

American Cruise Lines, American Independence

8 Night - Maine Coast & Harbors Cruise
Starting in Bangor ME, Day of Cruising the Maine Coast, Bar Harbor, Me, Rockland, ME / Camden, ME, Bath, ME, Boothbay Harbor, ME, Day of Cruising, Portland ME
2026 Sails: Jun 1, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 7, Sep 21, 2027: Jun 14, Jun 28, Jul 12, Jul 26, Aug 9, Aug 23, Sep 6, 2028: Aug 4, Aug 18, Sep 1, Sep 15, More...

Carnival Cruise Lines, Carnival Freedom

5 Night - Bahamas
Starting in Port Canaveral (Orlando), Fl, Nassau, Bahamas, Celebration Key, the Bahamas, Princess Cays, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Jun 1, More...

Carnival Cruise Lines, Carnival Venezia

9 Night - Eastern Caribbean
Starting in Manhattan, New York City, Celebration Key, the Bahamas, Nassau, Bahamas, Relaxaway, Half Moon Cay, Grand Turk, Manhattan, New York City
2026 Sails: Jun 1, More...

Celebrity Cruises, Celebrity Reflection

4 Night - Perfect Day Cococay & Key West
Starting in Fort Lauderdale, Florida, Key West, Florida, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jun 1, 2027: May 17, Aug 16, More...

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United States Cruise Departures