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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Princess Cruises, Sun Princess
Sun Princess Cruise Ship14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Costa Maya (Mahahual), Mexico, Cozumel, Mexico, Grand Cayman, Cayman Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, More...
Royal Caribbean International, Harmony of the Seas
Harmony of the Seas Cruises7 Night - Western Caribbean Cruise
Starting in Galveston, Texas, Roatan, Honduras, Puerto Costa Maya, Mexico, Cozumel, Mexico, Galveston, Texas
2026 Sails: Jan 18, Jan 25, Feb 1, Feb 8, Feb 15, Feb 22, Mar 1, More...
Royal Caribbean International, Independence of the Seas
Independence of the Seas Cruise Ship7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Falmouth, Jamaica, George Town, Grand Cayman, Cozumel, Mexico, Miami, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
Royal Caribbean International, Oasis of the Seas
Oasis of the Seas Cruise Ship6 Night - Western Caribbean Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Fort Lauderdale, Florida
2026 Sails: Jan 18, Mar 1, Mar 15, Mar 29, More...
Royal Caribbean International, Rhapsody of the Seas
Rhapsody of the Seas Cruise Ship6 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Jan 18, Apr 12, More...
Star of the Seas Cruises7 Night - Western Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Cozumel, Mexico, Roatan, Honduras, Puerto Costa Maya, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, Apr 26, Aug 30, Oct 11, More...
Royal Caribbean International, Symphony of the Seas
Symphony of the Seas Cruises7 Night - Eastern Caribbean Cruise
Starting in Miami, Florida, Philipsburg, St Maarten, Charlotte Amalie, St Thomas, Nassau, Bahamas, Miami, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
Carnival Cruise Lines, Carnival Legend
Carnival Legend Cruise Ship10 Night - Western Caribbean
Starting in Galveston, Tx, Cozumel, Mexico, Belize, Mahogany Bay, Roatan, Montego Bay, Jamaica, Grand Cayman, Cayman Islands, Galveston, Tx
2026 Sails: Jan 19, Apr 13, More...
Celebrity Cruises, Celebrity Reflection
Celebrity Reflection Cruises4 Night - Key West & Bahamas Cruise
Starting in Fort Lauderdale, Florida, Key West, Florida, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 19, More...
Queen Mary 2 Cruise Ship15 Night - New York to Los Angeles
Starting in New York, NY, Cartagena CO, Transit the Panama Canal, Panama (Full Transit), Fuerte Amador (tours to Panama City), Panama, Manzanillo, Mexico, Los Angeles, CA
2026 Sails: Jan 19, More...

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United States Cruise Departures