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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Celebrity Cruises, Celebrity Beyond
Celebrity Beyond Cruises7 Night - St. Thomas, St. Kitts & Puerto Plata
Starting in Miami, Florida, Puerto Plata, Dominican Republic, Charlotte Amalie, St Thomas, Basseterre, St Kitts and Nevis, Miami, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
Celebrity Cruises, Celebrity Constellation
Celebrity Constellation Cruise Ship7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Nassau, Bahamas, Tampa, Florida
2026 Sails: Jan 18, Mar 22, More...
Celebrity Cruises, Celebrity Silhouette
Celebrity Silhouette Cruise Ship6 Night - Grand Cayman, Mexico & Key West
Starting in Fort Lauderdale, Florida, Key West, Florida, George Town, Grand Cayman, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, Mar 15, Apr 12, More...
Celebrity Cruises, Celebrity Xcel
Celebrity Xcel Cruises7 Night - Bahamas, Mexico & Cayman Cruise
Starting in Fort Lauderdale, Florida, Bimini, Bahamas, Cozumel, Mexico, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Jan 18, Feb 15, Mar 1, Mar 15, Mar 29, Apr 12, More...
Crystal, Crystal Serenity
Crystal Serenity Cruise Ship11 Night - South Pacific
Starting in Honolulu, Nuku Hiva, Fakarava, Rangiroa, Moorea Island, Papeete (Tahiti)
2026 Sails: Jan 18, More...
Disney Fantasy Cruises5 Night - Bahamian Cruise from Port Canaveral with Pixar Day at Sea
Starting in Port Canaveral, Disney Lookout Cay, Nassau, Port Canaveral
2026 Sails: Jan 18, Feb 1, Feb 15, Mar 1, More...
Holland America Line, Rotterdam
Rotterdam Cruise Ship21 Night - Panama Canal & Southern Caribbean : Abc Islands
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida, Willemstad AN, Curacao, Kralendijk, Bonaire, Oranjestad, Aruba, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...
Holland America Line, Rotterdam
Rotterdam Cruise Ship12 Night - Panama Canal Discovery : Costa Rica & Greater Antilles
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Willemstad AN, Curacao, Enter Panama Canal Cristobal, Cruising Panama Canal and Gatun Lake, Gatun Lake, Panama, Cruising Gatun Lake and Panama Canal, Exit Panama Canal Cristobal, Colon, Panama, Puerto Limon (San Jose), Costa Rica, Falmouth, Jamaica, Georgetown, Cayman Islands, Fort Lauderdale, Florida
2026 Sails: Jan 18, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa Cruises6 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Jan 18, More...
MSC Cruises, MSC Meraviglia
MSC Meraviglia Cruises7 Night - Caribbean and Antilles
Starting in New York City (Brooklyn), New York, Port Canaveral (Orlando), Florida, Ocean Cay Msc Marine Reserve, Bahamas, Nassau, Bahamas, New York City (Brooklyn), New York
2026 Sails: Jan 18, Jan 25, Feb 1, Feb 15, Feb 22, Mar 1, Mar 15, Mar 22, Apr 12, More...

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United States Cruise Departures