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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Windstar, Star Seeker
Star Seeker13 Night - Ocean Crossings
Starting in Anchorage (Seward), Alaska
2026 Sails: Sep 2, More...
Windstar, Star Seeker
Star Seeker24 Night - Star Collector : Japan and North Pacific Crossing
Starting in Seward, Anchorage, Alaska, Tokyo, Shimizu, Shingu, Kagoshima, Scenic Cruising Hashima Island, Nagasaki, Busan, Karatsu, Hiroshima, Takamatsu, Kobe / Kyoto
2026 Sails: Sep 2, More...
Windstar, Star Seeker
Star Seeker14 Night - Ocean Crossing
Starting in Seward, Anchorage, Alaska, Tokyo
2026 Sails: Sep 2, More...
American Lines Tours, American Patriot Tours
American Patriot Tours8 Night - Great Lakes & Thousand Islands Cruise
Starting in Syracuse NY, Oswego, NY / Day of Cruising, Clayton, NY, Day of Cruising, Ogdensburg, NY, Rochester, NY, Day of Cruising the Welland Canal, Buffalo, NY
2026 Sails: Sep 3, Oct 11, 2027: May 2, Jun 23, Aug 21, Oct 5, 2028: May 1, Jun 22, Aug 20, Oct 4, More...
Carnival Cruise Lines, Carnival Miracle
Carnival Miracle7 Night - Alaska Inside Passage & Glacier
Starting in Seattle, Wa, Cruise Endicott Arm Fjord, Skagway, Ak, Juneau, Ak, Ketchikan, AK, Victoria CA, Canada, Seattle, Wa
2026 Sails: Sep 3, Sep 10, More...
Margaritaville at Sea, Margaritaville Paradise
Margaritaville Paradise4 Night - Key West & Nassau
Starting in Port of Palm Beach, Key West, FL, Nassau, Bahamas, Port of Palm Beach
2026 Sails: Sep 3, Oct 19, More...
MSC Cruises, MSC Seashore
MSC Seashore3 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Sep 3, Sep 17, Oct 1, Oct 15, Oct 29, More...
Norwegian Cruise Line, Norwegian Aqua
Norwegian Aqua5 Night - Bermuda - New York
Starting in New York City, Ny, Royal Naval Dockyard, Bermuda, New York City, Ny
2026 Sails: Sep 3, Sep 8, Sep 13, Sep 18, Sep 23, Sep 28, Oct 3, Oct 8, More...
Princess Cruises, Sapphire Princess
Sapphire Princess10 Night - Classic Canada & New England
Starting in Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, Sydney NS, Charlottetown, Canada, Saguenay, Canada, Quebec City, Canada
2026 Sails: Sep 3, More...
Princess Tours, Island Princess Tours
Island Princess Tours13 Night - Connoisseur Escorted - Tour Tb6
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 3, More...

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United States Cruise Departures