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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Ritz-Carlton Yacht Collection, Ilma
Ilma Cruises8 Night - Fort Lauderdale, Florida / San Juan
Starting in Fort Lauderdale, Florida, San Salvador, Grand Turk, Puerto Plata, Dominican Republic, St John VI, Virgin Gorda, San Juan
2025 Sails: Dec 1, More...
Royal Caribbean International (RCL), RCL Enchantment of the Seas
RCL Enchantment of the Seas Cruise Ship5 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Tampa, Florida
2025 Sails: Dec 1, Dec 6, Dec 15, More...
Royal Caribbean International (RCL), RCL Liberty of the Seas
RCL Liberty of the Seas Cruise Ship4 Night - Bahamas & Perfect Day Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 1, More...
Royal Caribbean International (RCL), RCL Navigator of the Seas
RCL Navigator of the Seas Cruise Ship4 Night - Catalina & Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2025 Sails: Dec 1, 2026: Jan 4, Feb 2, Mar 2, Mar 30, More...
Royal Caribbean International (RCL), RCL Quantum of the Seas
RCL Quantum of the Seas Cruises4 Night - Ensenada Cruise
Starting in Los Angeles, California, Catalina Island, California, Ensenada, Mexico, Los Angeles, California
2025 Sails: Dec 1, More...
Royal Caribbean International (RCL), RCL Radiance of the Seas
RCL Radiance of the Seas Cruise Ship4 Night - Bahamas & Perfect Day Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2025 Sails: Dec 1, Dec 15, More...
Royal Caribbean International (RCL), RCL Utopia of the Seas
RCL Utopia of the Seas Cruises4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Orlando (Port Canaveral), Fl
2025 Sails: Dec 1, Dec 8, More...
Royal Caribbean International (RCL), RCL Wonder of the Seas
RCL Wonder of the Seas Cruises4 Night - Bahamas & Perfect Day Cruise
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Miami, Florida
2025 Sails: Dec 1, Dec 15, More...
American Cruise Lines, American Legend
American Legend Cruises8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2025 Sails: Dec 2, Dec 9, Dec 16, Dec 23, Dec 30, 2026: Jan 6, Jan 13, Jan 20, Jan 27, Feb 3, Feb 10, Feb 17, Feb 24, Mar 3, Mar 10, Mar 17, More...
Margaritaville at Sea, Margaritaville Islander
Margaritaville Islander Cruises5 Night - Mexico Duo
Starting in Port Tampa Bay, Progreso, Mexico, Cozumel, Mexico, Port Tampa Bay
2025 Sails: Dec 2, Dec 17, 2026: Jan 14, Feb 6, Mar 4, Mar 18, Apr 1, May 4, Jun 15, Jul 27, Nov 30, Dec 28, 2027: Jun 14, Jul 26, More...

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United States Cruise Departures