United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Cruises, Star Princess

7 Night - Eastern Caribbean with Bahamas
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Fort Lauderdale, Florida
2026 Sails: Jan 17, More...

Princess Cruises, Star Princess

14 Night - Eastern / Western Caribbean Adventurer
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Fort Lauderdale, Florida, Roatan (Mahogany Bay, Honduras), Belize City, Belize, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Jan 17, More...

Royal Caribbean International, Adventure of the Seas

6 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, George Town, Grand Cayman, Falmouth, Jamaica, Grand Bahama Island, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Jan 17, More...

Royal Caribbean International, Allure of the Seas

8 Night - Eastern Caribbean & Perfect Day
Starting in Fort Lauderdale, Florida, Charlotte Amalie, St Thomas, Basseterre, St Kitts and Nevis, San Juan, Puerto Rico, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Jan 17, Feb 14, More...

Royal Caribbean International, Enchantment of the Seas

5 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Puerto Costa Maya, Mexico, Cozumel, Mexico, Tampa, Florida
2026 Sails: Jan 17, Jan 26, Jan 31, Feb 9, Feb 14, Feb 23, Feb 28, Mar 9, Mar 14, Mar 23, Mar 28, Apr 6, Apr 11, Apr 20, More...

Royal Caribbean International, Grandeur of the Seas

7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Roatan, Honduras, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Jan 17, Mar 14, Apr 11, More...

Royal Caribbean International, Icon of the Seas

7 Night - Eastern Caribbean & Perfect Day
Starting in Miami, Florida, Philipsburg, St Maarten, Charlotte Amalie, St Thomas, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Jan 17, Jan 31, Feb 14, Feb 28, Mar 14, Mar 28, Apr 11, Apr 25, May 16, May 30, Jun 27, Jul 11, Aug 1, Aug 8, Aug 22, Sep 12, Sep 19, Oct 3, Oct 24, Nov 7, Nov 21, Dec 5, Dec 19, 2027: Apr 24, More...

Viking River, Viking Mississippi

7 Night - New Orleans & Southern Charms
Starting in New Orleans, Louisiana, Darrow, Louisiana, St Francisville, Louisiana, Natchez, Mississippi, Vicksburg, Mississippi, Baton Rouge, Louisiana, New Orleans, Louisiana
2026 Sails: Jan 17, Dec 22, Dec 29, 2027: Jan 5, Jan 12, Dec 28, More...

American Cruise Lines, American Patriot

8 Night - Florida Gulf Coast & Keys Cruise
Starting in Tampa, Fl, Day of Cruising, Marco Island, FL, Key West, FL, Day of Cruising, Punta Gorda, FL, St Petersburg FL
2026 Sails: Jan 18, Jan 25, Feb 1, Feb 8, Feb 15, Feb 22, Mar 1, Mar 8, Mar 15, Mar 22, Mar 29, Apr 5, Apr 12, Apr 19, 2027: Jan 3, Jan 10, Jan 17, Jan 24, Jan 31, Feb 7, Feb 14, Feb 21, Feb 28, Mar 7, More...

Carnival Cruise Lines, Carnival Dream

14 Night - Journeys - Eastern Caribbean
Starting in Galveston, Tx, Key West, FL, Celebration Key, the Bahamas, San Juan, Puerto Rico, St Croix, US Virgin Islands, St Kitts, St Maarten, St Thomas, US Virgin Islands, Ocho Rios, Jamaica, Galveston, Tx
2026 Sails: Jan 18, More...

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United States Cruise Departures