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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Lindblad Expeditions, National Geographic Sea Lion
National Geographic Sea Lion14 Night - Voyage to Alaska, British Columbia and Haida Gwaii
Starting in Sitka / Embark Ship, Glacier Bay National Park / Inian Islands / Chichagof Island, Alaskas Inside Passage, Haida Gwaii, Inside Passage of British Columbia, Johnstone Strait and Alert Bay, British Columbia, Gulf Islands, British Columbia, Vancouver / Disembark Ship
2026 Sails: Sep 2, More...
Norwegian Cruise Line, Norwegian Joy
Norwegian Joy9 Night - Alaska - Seattle
Starting in Seattle, Wa, Ketchikan (Ward Cove), Ak, Juneau, Ak, Skagway, Ak, Icy Strait Point, Ak, Cruise Glacier Bay, Ak, Victoria CA, Canada, Seattle, Wa
2026 Sails: Sep 2, More...
Princess Tours, Discovery Princess Tours
Discovery Princess Tours10 Night - On Your Own - Tour Bbx
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Discovery Princess Tours
Discovery Princess Tours10 Night - Denali Explorer - Tour Ab3
Starting in Anchorage, Mount Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Discovery Princess Tours
Discovery Princess Tours10 Night - Denali Explorer - Tour Cb3
Starting in Fairbanks, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Discovery Princess Tours
Discovery Princess Tours10 Night - Denali Explorer - Tour Bb3
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Grand Princess Tours
Grand Princess Tours17 Night - Connoisseur Escorted - Tour Vb1
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Island Princess Tours
Island Princess Tours14 Night - Off the Beaten Path - Tour Pb7
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Princess Tours, Island Princess Tours
Island Princess Tours14 Night - National Parks Explorer - Tour Xb7
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Sep 2, More...
Regent Seven Seas, Seven Seas Explorer
Seven Seas Explorer7 Night - Gold Rush Legacy
Starting in Anchorage (Whittier), Cruising Hubbard Glacier, Sitka, Skagway, Juneau, Ketchikan, Cruising the Inside Passage, Vancouver
2026 Sails: Sep 2, 2027: Jun 2, Jun 16, Jun 30, More...

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United States Cruise Departures