United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Norwegian Cruise Line, Pride of America

Deal link -> Special

7 Night - Hawaii Hnl Inter Island
Starting in Honolulu, Hi, Kahului, Maui, Hi, Hilo, Hi, Kona, Hi, Nawiliwili, Kauai, Hawaii, Cruise Napali Coast, Hi, Honolulu, Hi
2026 Sails: Oct 17, Oct 24, Oct 31, Nov 7, Nov 14, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Jan 30, Feb 6, Feb 13, Feb 20, Feb 27, Mar 6, Mar 13, Mar 20, Mar 27, More...

Princess Cruises, Discovery Princess

7 Night - Mexican Riviera
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Oct 17, Oct 24, Oct 31, Nov 7, Nov 14, Nov 21, Nov 28, Dec 5, Dec 12, Dec 19, Dec 26, 2027: Jan 2, Jan 9, Jan 16, Jan 23, Feb 6, Feb 13, Feb 20, Feb 27, Apr 17, Apr 24, More...

Princess Cruises, Majestic Princess

7 Night - Canada & New England with Saint John
Starting in New York City (Manhattan or Brooklyn), New York, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, New York City (Manhattan or Brooklyn), New York
2026 Sails: Oct 17, More...

Princess Cruises, Regal Princess

7 Night - Eastern Caribbean with Turks & Caicos
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Fort Lauderdale, Florida
2026 Sails: Oct 17, More...

Princess Tours, Majestic Princess Tours

14 Night - Historic America - Tour 1A
Starting in Washington DC, Williamsburg, Virginia, Staunton, Virginia, Gettysburg, Pennsylvania, Philadelphia, Pennsylvania, New York City (Manhattan or Brooklyn), New York, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, New York City (Manhattan or Brooklyn), New York
2026 Sails: Oct 17, More...

Royal Caribbean, Allure of the Seas

8 Night - Southern Caribbean & Perfect Day
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Oranjestad, Aruba, Perfect Day Cococay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 17, More...

Royal Caribbean, Enchantment of the Seas

7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Roatan, Honduras, Belize City, Belize, Puerto Costa Maya, Mexico, Cozumel, Mexico, Tampa, Florida
2026 Sails: Oct 17, More...

Royal Caribbean, Freedom of the Seas

5 Night - Bahamas & Perfect Day Cruise
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Miami, Florida
2026 Sails: Oct 17, More...

Royal Caribbean, Harmony of the Seas

7 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Charlotte Amalie, St Thomas, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Oct 17, Nov 14, More...

Royal Caribbean, Icon of the Seas

Deal link -> Special

7 Night - Western Caribbean & Perfect Day
Starting in Miami, Florida, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Oct 17, Oct 31, Nov 14, Nov 28, Dec 12, Dec 26, 2027: Jan 9, Jan 23, Feb 6, Feb 20, Mar 6, Mar 20, Apr 3, Apr 17, May 22, Jun 12, Jul 3, Jul 24, More...

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United States Cruise Departures