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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Carnival Cruise Lines, Carnival Vista
Carnival Vista8 Night - Eastern Caribbean
Starting in Port Canaveral (Orlando), Fl, Grand Turk, San Juan, Puerto Rico, St Maarten, St Thomas, US Virgin Islands, Port Canaveral (Orlando), Fl
2026 Sails: Mar 7, Apr 4, More...
Celebrity Cruises, Celebrity Silhouette
Celebrity Silhouette8 Night - Aruba, Curacao & Cayman Cruise
Starting in Fort Lauderdale, Florida, Willemstad AN, Curacao, Oranjestad, Aruba, George Town, Grand Cayman, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit7 Night - Bahamas & Grand Turk Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Bimini, Bahamas, Grand Turk, Turks and Caicos, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...
Holland America, Koningsdam
Koningsdam8 Night - Eastern Caribbean : Greater Antilles & Leeward Islands
Starting in Fort Lauderdale, Florida, Amber Cove, Dominican Republic, San Juan, Puerto Rico, Philipsburg, Sint Maarten, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...
Holland America, Nieuw Statendam
Nieuw Statendam14 Night - Eastern & Western Caribbean : San Juan & Mexico
Starting in Fort Lauderdale, Florida, Grand Turk, Turks and Caicos, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...
Holland America, Nieuw Statendam
Nieuw Statendam7 Night - Eastern Caribbean : San Juan & St. Thomas
Starting in Fort Lauderdale, Florida, Grand Turk, Turks and Caicos, San Juan, Puerto Rico, St Thomas, US Virgin Islands, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Mar 7, Mar 28, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa7 Night - Caribbean Western Roundtrip from Orlando (Port Canaveral)
Starting in Port Canaveral (Orlando), Florida, Cozumel, Mexico, George Town, Cayman Islands, Falmouth, Jamaica, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Mar 7, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa14 Night - Caribbean Western Roundtrip from Orlando (Port Canaveral)
Starting in Port Canaveral (Orlando), Florida, Cozumel, Mexico, George Town, Cayman Islands, Falmouth, Jamaica, Nassau, Bahamas, Port Canaveral (Orlando), Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Puerto Plata, Dominican Republic, Port Canaveral (Orlando), Florida
2026 Sails: Mar 7, More...
Oceania Cruises, Oceania Vista
Oceania Vista16 Night - Pacific Lagoons & Retreats
Starting in San Diego, Honolulu, Kailua-Kona, Nuku Hiva, Rangiroa, Moorea, Papeete (Tahiti)
2026 Sails: Mar 7, More...
Princess Cruises, Enchanted Princess
Enchanted Princess20 Night - Caribbean Explorer
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, St Thomas, US Virgin Islands, Antigua, St Maarten, St Kitts, Tortola, British Virgin Islands, Fort Lauderdale, Florida, Princess Cays, Bahamas, St Thomas, US Virgin Islands, Dominica, Barbados, Martinique, Antigua, Fort Lauderdale, Florida
2026 Sails: Mar 7, More...

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United States Cruise Departures