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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Disney Cruise Line, Disney Fantasy
Disney Fantasy5 Night - Very Merrytime Western Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Castaway Cay, Cozumel, Mexico, Port Canaveral
2026 Sails: Oct 9, Nov 20, Dec 18, 2027: Jan 29, More...
Royal Caribbean, Ovation Of The Seas
Ovation Of The Seas3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Oct 9, Oct 23, Oct 30, Nov 13, Nov 27, Dec 11, Dec 18, More...
Carnival Cruise Lines, Carnival Venezia
Carnival Venezia8 Night - Southern Caribbean
Starting in Port Canaveral (Orlando), Fl, Bonaire, Aruba, Celebration Key, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Oct 10, More...
Disney Cruise Line, Disney Destiny
Disney Destiny7 Night - Halloween On the High Seas Western Caribbean Cruise from Fort Lauderdale
Starting in Port Everglades, Disney Lookout Cay, Falmouth, George Town, Grand Cayman, Cozumel, Mexico, Port Everglades
2026 Sails: Oct 10, More...
Disney Cruise Line, Disney Treasure
Disney Treasure7 Night - Eastern Caribbean Cruise from Port Canaveral
Starting in Port Canaveral, Tortola, St Thomas, US Virgin Islands, Castaway Cay, Port Canaveral
2026 Sails: Oct 10, Oct 24, 2027: Mar 27, Apr 10, Apr 24, May 8, May 22, More...
Disney Cruise Line, Disney Wonder
Disney Wonder3 Night - Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2026 Sails: Oct 10, Dec 15, 2027: Feb 12, Feb 26, More...
Holland America, Zuiderdam
Zuiderdam7 Night - Canada & New England : Unesco Sites & Quebecois Nights
Starting in Boston, Massachusetts, Portland ME, Halifax, Nova Scotia, Canada, Sydney NS, Nova Scotia, Canada, Charlottetown, Prince Edward Island, Canada, Cruising Gulf of St Lawrence, Cruising the Saint Lawrence River, Quebec City, Quebec, Canada
2026 Sails: Oct 10, More...
Margaritaville at Sea, Margaritaville Islander
Margaritaville Islander7 Night - New Orleans & Mexico
Starting in Port Tampa Bay, New Orleans, La, Cozumel, Mexico, Progreso, Mexico, Port Tampa Bay
2026 Sails: Oct 10, More...
Princess Cruises, Majestic Princess
Majestic Princess7 Night - Canada & New England with Saint John
Starting in New York City (Manhattan or Brooklyn), New York, Newport, Rhode Island, Boston, Massachusetts, Portland ME, Saint John NB (Bay of Fundy), Halifax, Canada, New York City (Manhattan or Brooklyn), New York
2026 Sails: Oct 10, More...
Princess Cruises, Regal Princess
Regal Princess7 Night - Eastern Caribbean with Turks & Caicos
Starting in Fort Lauderdale, Florida, Princess Cays, Bahamas, Amber Cove, Dominican Republic, Grand Turk, Turks and Caicos, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Oct 10, More...

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United States Cruise Departures