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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Celebrity Cruises, Celebrity Reflection
Celebrity Reflection3 Night - Key West & Bahamas Cruise
Starting in Fort Lauderdale, Florida, Key West, Florida, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: May 1, May 29, Jun 12, Jun 26, Jul 10, Aug 7, Aug 21, 2027: Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Nov 12, 2028: Mar 17, Mar 31, Apr 14, More...
Margaritaville at Sea, Margaritaville Paradise
Margaritaville Paradise2 Night - Grand Bahama Getaway
Starting in Port of Palm Beach, Freeport, Grand Bahama, Port of Palm Beach
2026 Sails: May 1, Dec 14, Dec 16, 2027: Jan 15, Feb 12, Mar 5, Apr 30, Aug 20, More...
Royal Caribbean, Adventure of the Seas
Adventure of the Seas8 Night - Eastern Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, St Croix, US Virgin Islands, Philipsburg, St Maarten, San Juan, Puerto Rico, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: May 1, More...
Royal Caribbean, Anthem of the Seas
Anthem of the Seas8 Night - Hawaii Cruise
Starting in Honolulu, Oahu, Hawaii, Kailua Kona, Hawaii, Vancouver, British Columbia
2026 Sails: May 1, More...
Navigator of the Seas7 Night - Ensenada, Cabo & Mazatlan
Starting in Los Angeles, California, Ensenada, Mexico, Cabo San Lucas, Mexico, Mazatlan, Mexico, Los Angeles, California
2026 Sails: May 1, May 15, May 29, Jun 12, Jun 26, Jul 10, Jul 24, Aug 21, Sep 4, Sep 18, Sep 25, More...
Royal Caribbean, Quantum of the Seas
Quantum of the Seas7 Night - Cabo Overnight & Ensenada
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: May 1, Aug 21, Sep 4, More...
Royal Caribbean, Wonder of the Seas
Wonder of the Seas7 Night - Eastern Caribbean & Perfect Day
Starting in Miami, Florida, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Charlotte Amalie, St Thomas, Miami, Florida
2026 Sails: May 1, More...
American Lines Tours, American Symphony Tours
American Symphony Tours11 Night - Smoky Mountains National Park
Starting in Knoxville, TN, Pigeon Forge, TN, Great Smoky Mountain National Park, Chattanooga, TN, Decatur, AL, Florence, AL, Savannah, TN, Paducah, KY, Cruising Lake Barkley and the Cumberland River, Nashville, TN
2026 Sails: May 2, May 16, May 30, Jun 13, Sep 19, Oct 3, Oct 17, More...
Carnival Cruise Lines, Carnival Elation
Carnival Elation5 Night - Bahamas
Starting in Jacksonville, FL, Princess Cays, the Bahamas, Celebration Key, the Bahamas, Jacksonville, FL
2026 Sails: May 2, May 16, Jun 22, Jun 27, Jul 25, Aug 17, Aug 22, Sep 5, Sep 14, 2027: Feb 20, Mar 20, Jun 21, Jul 5, Aug 2, Aug 30, 2028: Jan 3, Feb 14, Feb 28, Mar 13, Mar 27, Apr 10, More...
Carnival Cruise Lines, Carnival Jubilee
Carnival Jubilee7 Night - Western Caribbean
Starting in Galveston, Tx, Cozumel, Mexico, Costa Maya, Mexico, Mahogany Bay, Roatan, Galveston, Tx
2026 Sails: May 2, More...

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United States Cruise Departures