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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Celebrity Apex7 Night - Key West, Bahamas & Grand Turk
Starting in Orlando (Port Canaveral), Fl, Key West, Florida, Bimini, Bahamas, Puerto Plata, Dominican Republic, Grand Turk, Turks and Caicos, Orlando (Port Canaveral), Fl
2026 Sails: Feb 21, Mar 21, Apr 4, Apr 18, More...
Celebrity Cruises, Celebrity Silhouette
Celebrity Silhouette8 Night - Aruba, Curacao & Grand Cayman
Starting in Fort Lauderdale, Florida, George Town, Grand Cayman, Oranjestad, Aruba, Willemstad AN, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit5 Night - Bahamas Getaway Cruise
Starting in Fort Lauderdale, Florida, Nassau, Bahamas, Bimini, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 21, Apr 4, More...
Holland America, Nieuw Statendam
Nieuw Statendam14 Night - Western & Eastern Caribbean : Mexico & Bahamas
Starting in Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Fort Lauderdale, Florida, Half Moon Cay, Bahamas, Grand Turk, Turks and Caicos, Amber Cove, Dominican Republic, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
MSC Cruises, MSC Grandiosa
MSC Grandiosa7 Night - Caribbean Roundtrip from Orlando (Port Canaveral)
Starting in Port Canaveral (Orlando), Cozumel, Mexico, George Town, Cayman Islands, Montego Bay, Jamaica, Nassau, Bahamas, Port Canaveral (Orlando)
2026 Sails: Feb 21, Mar 21, More...
Norwegian Cruise Line, Norwegian Encore
Norwegian Encore7 Night - Western Caribbean - Miami
Starting in Miami, Fl, Harvest Caye, Belize, Roatan Bay Islands, Honduras, Costa Maya, Mexico, Great Stirrup Cay, Bahamas, Miami, Fl
2026 Sails: Feb 21, More...
Princess Cruises, Caribbean Princess
Caribbean Princess12 Night - Southern Caribbean with Panama
Starting in Fort Lauderdale, Florida, Grand Cayman, Cayman Islands, Falmouth, Jamaica, Limon, Costa Rica, Colon, Panama, Aruba, Curacao, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
Princess Cruises, Star Princess
Star Princess7 Night - Western Caribbean with Mexico
Starting in Fort Lauderdale, Florida, Belize City, Belize, Roatan (Mahogany Bay, Honduras), Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Feb 21, More...
Regent Seven Seas, Seven Seas Grandeur
Seven Seas Grandeur7 Night - Secret Shores & Cultural Gems
Starting in Miami, Cruising the Florida Straits, Costa Maya, Mexico, Belize City, Roatan, Cozumel, Mexico, Cruising the Florida Straits, Miami
2026 Sails: Feb 21, More...
Royal Caribbean, Explorer of the Seas
Explorer of the Seas5 Night - Western Caribbean Cruise
Starting in Orlando (Port Canaveral), Fl, Puerto Costa Maya, Mexico, Cozumel, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Feb 21, More...

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United States Cruise Departures