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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Michigan : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Royal Caribbean, Utopia of the Seas
Utopia of the Seas4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Nov 9, More...
Virgin Voyages, Scarlet Lady
Scarlet Lady5 Night - Grand Cayman & Bimini Beach Club
Starting in Miami, Florida, George Town, Cayman Islands, The Beach Club at Bimini, Bahamas, Miami, Florida
2026 Sails: Nov 9, 2027: Mar 29, More...
American Cruise Lines, American Symphony
American Symphony7 Night - Gulf Coast Cruise
Starting in New Orleans, La, Day of Cruising, Gulfport / Ship Island, MS, Biloxi, MS, Ocean Springs, MS, Mobile, Al, Pensacola, FL
2026 Sails: Nov 10, Dec 8, Dec 20, 2027: Feb 12, Feb 24, Mar 8, Mar 20, Apr 1, Dec 10, Dec 22, 2028: Feb 20, Mar 3, Mar 15, Mar 27, More...
Rotterdam21 Night - Eastern & Western Caribbean : Leeward Islands & Mexico
Starting in Fort Lauderdale, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Roseau, Dominica, Castries, Saint Lucia, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida, RelaxAway, Half Moon Cay, Bahamas, Falmouth, Jamaica, Mahogany Bay, Roatan, Honduras, Belize City, Belize, Costa Maya, Mexico, Cozumel, Mexico, Fort Lauderdale, Florida
2026 Sails: Nov 10, More...
Rotterdam11 Night - Eastern Caribbean : Windward & Leeward Islands
Starting in Fort Lauderdale, Florida, Philipsburg, Sint Maarten, St Johns AG, Antigua, Roseau, Dominica, Castries, Saint Lucia, Basseterre, St Kitts and Nevis, St Thomas, US Virgin Islands, RelaxAway, Half Moon Cay, Bahamas, Fort Lauderdale, Florida
2026 Sails: Nov 10, Dec 1, More...
Royal Caribbean, Harmony of the Seas
Harmony of the Seas4 Night - Bahamas & Perfect Day Cruise
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Nassau, Bahamas, Orlando (Port Canaveral), Fl
2026 Sails: Nov 10, Dec 19, More...
American Cruise Lines, American Ranger
American Ranger8 Night - Potomac River & Chesapeake Bay Cruise
Starting in Washington, DC, Day of Cruising Chesapeake Bay, Williamsburg / Yorktown, VA, Cruising the Chesapeake Bay, Cambridge, MD, St Michaels, MD, Annapolis, MD, Baltimore, MD
2026 Sails: Nov 11, More...
Crystal Cruises, Crystal Symphony
Crystal Symphony13 Night - The Americas & Caribbean
Starting in Fort Lauderdale, New Orleans, Cozumel, Quintana Roo, Roatan Island, Santo Tomas, Montego Bay, Fort Lauderdale
2026 Sails: Nov 11, More...
Zuiderdam17 Night - Southern Caribbean : Cabo Rojo & Abc Islands
Starting in Miami, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Cabo Rojo, Dominican Republic, RelaxAway, Half Moon Cay, Bahamas, Miami, Florida, Key West, Florida, Ocho Rios, Jamaica, Georgetown, Cayman Islands, Cozumel, Mexico, Miami, Florida
2026 Sails: Nov 11, More...
Zuiderdam10 Night - Southern Caribbean : Cabo Rojo & Abc Islands
Starting in Miami, Florida, Kralendijk, Bonaire, Willemstad AN, Curacao, Oranjestad, Aruba, Cabo Rojo, Dominican Republic, RelaxAway, Half Moon Cay, Bahamas, Miami, Florida
2026 Sails: Nov 11, More...

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United States Cruise Departures