United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Departing from
United States
Cruise Specials

Princess Tours, Discovery Princess Tours

15 Night - Off the Beaten Path - Tour Qb8
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jun 19, Jul 3, More...

Royal Caribbean, Navigator of the Seas

7 Night - Cabo, Vallarta & Mazatlan
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Mazatlan, Mexico, Puerto Vallarta, Mexico, Los Angeles, California
2026 Sails: Jun 19, Jul 3, Jul 17, More...

Royal Caribbean, Oasis of the Seas

9 Night - Eastern Caribbean & Perfect Day
Starting in Cape Liberty, Nj (Ny Metro), Nassau, Bahamas, Perfect Day Cococay, Bahamas, Puerto Plata, Dominican Republic, Cape Liberty, Nj (Ny Metro)
2026 Sails: Jun 19, 2027: Jun 18, More...

Royal Caribbean, Ovation Of The Seas

7 Night - Southbound Alaska & Hubbard Glacier
Starting in Seward, Alaska, Hubbard Glacier (Cruising), Juneau, Alaska, Skagway, Alaska, Icy Strait Point, Alaska, Vancouver, British Columbia
2026 Sails: Jun 19, More...

Royal Caribbean, Quantum of the Seas

7 Night - Cabo Overnight & Ensenada
Starting in Los Angeles, California, Cabo San Lucas, Mexico, Ensenada, Mexico, Los Angeles, California
2026 Sails: Jun 19, Jul 3, Jul 17, More...

Royal Caribbean, Voyager of the Seas

7 Night - Alaska Adventure Cruise
Starting in Seattle, Washington, Juneau, Alaska, Skagway, Alaska, Endicott Arm and Dawes Glacier, Victoria CA, Canada, Seattle, Washington
2026 Sails: Jun 19, More...

American Lines Tours, American Harmony Tours

14 Night - National Parks & Legendary Rivers
Starting in Jackson, WY, Grand Teton and Yellowstone National Parks, Yellowstone National Park, Travel toward Glacier National Park, Glacier National Park, Travel to Clarkston, Begin Your Columbia River and Snake Rivers Cruise / Clarkston, WA, Richland, WA, Cruising the Columbia River Gorge, Hood River, OR, Kalama, WA, Astoria, Or, Day of Cruising, Portland-OR
2026 Sails: Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, More...

Carnival Cruise Lines, Carnival Freedom

5 Night - Bahamas
Starting in Port Canaveral (Orlando), Fl, Relaxaway, Half Moon Cay, Nassau, Bahamas, Celebration Key, the Bahamas, Port Canaveral (Orlando), Fl
2026 Sails: Jun 20, 2027: Jan 2, Feb 13, Apr 10, Apr 24, More...

Carnival Cruise Lines, Carnival Horizon

8 Night - Southern Caribbean
Starting in Miami, Fl, Aruba, Bonaire, Curacao, Miami, Fl
2026 Sails: Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, Nov 21, Dec 5, More...

Disney Cruise Line, Disney Destiny

7 Night - Western Caribbean Cruise from Fort Lauderdale
Starting in Port Everglades, Disney Lookout Cay, Castaway Cay, Cozumel, Mexico, George Town, Grand Cayman, Port Everglades
2026 Sails: Jun 20, More...

<= Back

More =>

United States Cruise Departures