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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Royal Caribbean, Star of the Seas
Star of the Seas7 Night - Western Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, Puerto Costa Maya, Mexico, Roatan, Honduras, Cozumel, Mexico, Orlando (Port Canaveral), Fl
2026 Sails: Sep 20, More...
American Cruise Lines, American Eagle
American Eagle8 Night - Hudson River Fall Foliage Cruise
Starting in New York, NY, Day of Cruising the Hudson River, Sleepy Hollow, NY, West Point, NY, Kingston, NY / Hyde Park, NY, Catskill, NY, Day of Cruising, Albany NY
2026 Sails: Sep 21, Oct 5, Oct 19, 2027: Oct 4, Oct 18, 2028: Oct 2, Oct 16, More...
Disney Cruise Line, Disney Destiny
Disney Destiny5 Night - Halloween On the High Seas Bahamian Cruise from Fort Lauderdale
Starting in Port Everglades, Castaway Cay, Nassau, Disney Lookout Cay, Port Everglades
2026 Sails: Sep 21, More...
Disney Cruise Line, Disney Magic
Disney Magic4 Night - Baja Cruise from San Diego
Starting in San Diego, Ensenada, San Diego
2026 Sails: Sep 21, Oct 12, More...
Margaritaville at Sea, Margaritaville Paradise
Margaritaville Paradise4 Night - Key West & Grand Bahama
Starting in Port of Palm Beach, Key West, Florida, Freeport, Grand Bahama, Port of Palm Beach
2026 Sails: Sep 21, More...
MSC Cruises, MSC Poesia
MSC Poesia7 Night - Alaska
Starting in Seattle, Washington, Ketchikan, Alaska, Sitka, Alaska, Endicott Arm and Dawes Glacier, Juneau, Alaska, Victoria CA, Canada, Seattle, Washington
2026 Sails: Sep 21, More...
MSC Cruises, MSC Seaside
MSC Seaside7 Night - Caribbean and Antilles
Starting in Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida, Nassau, Bahamas, Ocean Cay Msc Marine Reserve, Bahamas, Miami, Florida
2026 Sails: Sep 21, Oct 5, Oct 12, Oct 19, More...
Royal Caribbean, Jewel of the Seas
Jewel of the Seas4 Night - Bahamas Getaway Cruise
Starting in Fort Lauderdale, Florida, Bimini, Bahamas, Grand Bahama Island, Bahamas, Nassau, Bahamas, Fort Lauderdale, Florida
2026 Sails: Sep 21, More...
Royal Caribbean, Ovation Of The Seas
Ovation Of The Seas3 Night - Ensenada Cruise
Starting in Los Angeles, California, Ensenada, Mexico, Los Angeles, California
2026 Sails: Sep 21, More...
Royal Caribbean, Wonder of the Seas
Wonder of the Seas4 Night - Bahamas & Perfect Day Cruise
Starting in Miami, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, Miami, Florida
2026 Sails: Sep 21, Oct 12, More...

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United States Cruise Departures