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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Princess Tours, Grand Princess Tours
Grand Princess Tours11 Night - Denali Explorer - Tour Db4
Starting in Anchorage, Denali Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 14, Aug 25, More...
American Cruise Lines, American Legend
American Legend8 Night - Maine Coast & Harbors Cruise
Starting in Portland ME, Day of Cruising the Maine Coast, Bath, ME, Boothbay Harbor, ME, Rockland, ME / Camden, ME, Bar Harbor, Me, Bucksport, ME, Bangor ME
2026 Sails: Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
Lindblad Expeditions Tours, National Geographic Sea Bird Tours
National Geographic Sea Bird Tours5 Night - Alaska Escape : Leconte Bay, Wrangell and Misty Fjords
Starting in Juneau / Embark Ship, LeConte Bay or Endicott Arm, Sumner Strait, Wrangell, Misty Fjords National Monument, Ketchikan / Disembark Ship
2026 Sails: Jul 15, Aug 4, More...
Norwegian Cruise Line, Norwegian Spirit
Norwegian Spirit16 Night - Alaska
Starting in Honolulu, Hi, Hilo, Hi, Kahului, Maui, Hi, Nawiliwili, Kauai, Hawaii, Icy Strait Point, Ak, Haines, AK, Sitka, Ak, Ketchikan (Ward Cove), Ak, Vancouver, Canada
2026 Sails: Jul 15, More...
Princess Cruises, Island Princess
Island Princess7 Night - Voyage of the Glaciers with Glacier Bay (Southbound)
Starting in Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, Jul 29, Aug 12, Aug 26, Sep 9, More...
Princess Tours, Coral Princess Tours
Coral Princess Tours14 Night - Off the Beaten Path - Tour Pb7
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, More...
Princess Tours, Coral Princess Tours
Coral Princess Tours14 Night - National Parks Explorer - Tour Xb7
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, More...
Princess Tours, Discovery Princess Tours
Discovery Princess Tours17 Night - Connoisseur Escorted - Tour Vb1
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Kenai Princess Wilderness Lodge, Copper River Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Icy Strait Point, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, More...
Princess Tours, Grand Princess Tours
Grand Princess Tours10 Night - On Your Own - Tour Bbx
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, Aug 26, More...
Princess Tours, Grand Princess Tours
Grand Princess Tours10 Night - Denali Explorer - Tour Bb3
Starting in Fairbanks, Denali Princess Wilderness Lodge, Mount Mckinley Princess Wilderness Lodge, Anchorage (Whittier), Alaska, Hubbard Glacier (Scenic Cruising), Alaska, Glacier Bay National Park (Scenic Cruising), Alaska, Skagway, Alaska, Juneau, Alaska, Ketchikan, Alaska, Vancouver, Canada
2026 Sails: Jul 15, More...

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United States Cruise Departures