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United States Cruise Departures

Cruises that depart from North America: United States

Cruises that visit United States

See all River Cruises that depart from United States

Click on a cruise ship itinerary sailing from United States (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just United States), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Alabama : Alaska : California : Florida : Hawaii : Illinois : Kentucky : Louisiana : Maine : Maryland : Massachusetts : Michigan : Minnesota : Missouri : New Jersey : New York : Oklahoma : Oregon : Pennsylvania : Rhode Island : South Carolina : Tennessee : Texas : Virginia : Washington : Washington DC : Wisconsin : Wyoming

Departing from
United States
Cruise Specials

Celebrity Cruises, Celebrity Beyond
Celebrity Beyond7 Night - Tortola, St. Maarten & Puerto Plata
Starting in Miami, Florida, Puerto Plata, Dominican Republic, Tortola, Philipsburg, St Maarten, Miami, Florida
2026 Sails: Oct 25, More...
Celebrity Cruises, Celebrity Summit
Celebrity Summit7 Night - Western Caribbean Cruise
Starting in Tampa, Florida, Cozumel, Mexico, Belize City, Belize, Puerto Costa Maya, Mexico, Tampa, Florida
2026 Sails: Oct 25, Dec 6, 2027: Feb 28, Mar 14, Mar 28, More...
EXPLORA III7 Night - A Journey of Caribbean Adventure & Shimmering Tropical Harmony
Starting in Miami, St John VI (Cruz Bay), US Virgin Islands, St Johns AG, Antigua, Terre-De-Haut, St Maarten / Philipsburg, San Juan
2026 Sails: Oct 25, Nov 22, More...
EXPLORA III14 Night - An Extended Journey of Maritime Soul & Island Zest
Starting in Miami, St John VI (Cruz Bay), US Virgin Islands, St Johns AG, Antigua, Terre-De-Haut, St Maarten / Philipsburg, San Juan, Tortola / Road Town, Basseterre, Gustavia, Road Bay, Miami
2026 Sails: Oct 25, More...
MSC Cruises, MSC Seashore
MSC Seashore4 Night - Caribbean and Antilles
Starting in Port Canaveral (Orlando), Florida, Ocean Cay Msc Marine Reserve, Bahamas, Nassau, Bahamas, Port Canaveral (Orlando), Florida
2026 Sails: Oct 25, More...
Norwegian Cruise Line, Norwegian Prima
Norwegian Prima7 Night - Western Caribbean - Port Canaveral
Starting in Orlando Beaches / Port Canaveral, Fl, Great Stirrup Cay, Bahamas, Falmouth, Jamaica, George Town, Cayman Islands, Cozumel, Mexico, Orlando Beaches / Port Canaveral, Fl
2026 Sails: Oct 25, More...
Royal Caribbean, Allure of the Seas
Allure of the Seas7 Night - Eastern Caribbean & Perfect Day
Starting in Miami, Florida, Nassau, Bahamas, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Miami, Florida
2026 Sails: Oct 25, More...
Royal Caribbean, Oasis of the Seas
Oasis of the Seas9 Night - Eastern Caribbean & Perfect Day
Starting in Cape Liberty, Nj (Ny Metro), Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Puerto Plata, Dominican Republic, Cape Liberty, Nj (Ny Metro)
2026 Sails: Oct 25, More...
Royal Caribbean, Serenade of the Seas
Serenade of the Seas7 Night - Ensenada, Cabo & La Paz Cruise
Starting in San Diego, California, La Paz, Mexico, Cabo San Lucas, Mexico, Ensenada, Mexico, San Diego, California
2026 Sails: Oct 25, More...
Royal Caribbean, Star of the Seas
Star of the Seas7 Night - Eastern Caribbean & Perfect Day
Starting in Orlando (Port Canaveral), Fl, Perfect Day Cococay, Bahamas, San Juan, Puerto Rico, Philipsburg, St Maarten, Orlando (Port Canaveral), Fl
2026 Sails: Oct 25, More...

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United States Cruise Departures