Italy Cruise Departures

Cruises that depart from Mediterranean: Italy

Cruises that visit Italy

See all River Cruises that depart from Italy

Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.

Related areas: Ancona : Bari : Brindisi : Cagliari : Catania : Cernobbio : Civitavecchia : Fusina : Genoa : La Spezia : Lake Como : Livorno : Marghera : Messina : Milan : Naples : Napoli : Olbia : Palermo : Ravenna : Rome : Savona : Taranto : Trieste : Venice

Viking Ocean, Viking Sea

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Chioggia)
2026 Sails: Aug 4, More...

Viking Ocean, Viking Vesta

7 Night - Venice, the Adriatic & Greece
Starting in Venice (Fusina), Split, Dubrovnik, Croatia, Kotor, Corfu (Kerkyra), Katakolon (Olympia), Athens (Piraeus)
2026 Sails: Aug 4, Sep 29, Nov 25, More...

MSC Cruises, MSC Armonia

7 Night - Mediterranean
Starting in Brindisi (Lecce), Italy, Split, Croatia, Venice / Marghera, Italy, Dubrovnik, Croatia, Corfu, Greece, Kotor, Montenegro, Brindisi (Lecce), Italy
2026 Sails: Aug 7, More...

Norwegian Line Tours, Norwegian Viva Tours

12 Night - Pre Venice Cruisetour
Starting in At Hotel, Venice (Ravenna), Italy, Dubrovnik, Croatia, Kotor, Montenegro, Amalfi Coast (Salerno), Italy, Civitavecchia Rome, Italy, Livorno / Florence / Pisa, Italy, Nice / Monaco (Villefranche), France, Palma Majorca, Spain, Barcelona, Spain
2026 Sails: Aug 7, More...

Costa Cruise Lines, Costa Deliziosa

14 Night - Eastern Mediterranean from Marghera
Starting in Marghera, Bari, Santorini, Mykonos, Katakolon, Marghera, Bari, Corfu, Zakynthos, Argostoli / Cephalonia, Dubrovnik, Croatia, Split, Croatia, Marghera
2026 Sails: Aug 8, More...

SeaDream Yacht Club, SeaDream I

11 Night - Yachting the Adriatic & Greek Isles Cruise
Starting in Venice, Piran, Hvar, Dubrovnik, Croatia, Kotor, Corfu, Syvota, Galaxidi (Delphi), Corinth Canal Transit, Tinos, Kythnos, Athens (Piraeus)
2026 Sails: Aug 8, More...

Princess Tours, Sun Princess Tours

27 Night - Classic Italy - Tour 4C
Starting in Venice, Italy, Florence, Italy, Rome, Italy, Civitavecchia (for Rome), Italy, Naples, Italy (for Capri and Pompeii), Crete (Chania), Greece, Kusadasi, Turkey (for Ephesus), Mykonos, Greece, Athens (Piraeus), Greece, Santorini, Greece, Montenegro, Corfu, Greece, Sicily (Messina), Italy, Barcelona, Spain, Mallorca (Palma), Spain, Marseille (Provence), France, Corsica (Ajaccio), France, Genoa (for Cinque Terre), Italy, La Spezia (for Florence / Pisa), Italy, Civitavecchia (for Rome), Italy
2026 Sails: Aug 9, More...

Silversea, Silver Ray

6 Night - Civitavecchia to Monte Carlo
Starting in Civitavecchia (Rome), Porto Santo Stefano, Livorno (Tuscany), Portofino, Toulon, Monte Carlo
2026 Sails: Aug 9, More...

Cunard Line, Queen Victoria

14 Night - Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain, Ibiza, Spain, Cagliari, Sardinia, Italy, Messina Strait, Italy (Transit), Messina, Sicily, Italy, Salerno (tours to Capri or Pompeii), Italy, Amalfi Coast Sail By, IT, Civitavecchia (tours to Rome), Italy
2026 Sails: Aug 10, More...

Cunard Line, Queen Victoria

7 Night - Western Mediterranean
Starting in Civitavecchia (tours to Rome), Italy, Tarragona, Spain, Palma De Mallorca, Spain, Villefranche, France, Marseille, France, Barcelona, Spain
2026 Sails: Aug 10, More...

<= Back

More =>