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Lake Como Cruise Departures

Cruises that depart from Mediterranean: Italy: Lake Como

Cruises that visit Lake Como

See all River Cruises that depart from Lake Como

Click on a cruise ship itinerary sailing from Lake Como (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Lake Como), please visit: Cruise Search or try our Virtual Cruise Advisor™.


Avalon View Tours11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, Apr 14, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, More...
Avalon View Tours18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 29, Oct 13, Oct 27, More...
Avalon Envision Tours11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Apr 2, Apr 16, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 6, Aug 20, Sep 17, Oct 15, Oct 29, Nov 12, 2028: Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Jun 30, Aug 11, Aug 25, More...
Avalon Envision Tours18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Apr 2, Apr 16, May 14, May 28, Jun 25, Jul 9, Jul 23, Aug 20, Oct 15, Oct 29, 2028: Apr 7, May 5, May 19, Jun 2, Aug 11, Aug 25, Sep 8, Oct 6, Oct 20, Nov 3, More...
Wind Spirit Tours12 Night - Lake Como & Adriatic Romance Cruise Tour
Starting in Royal Victoria Varenna Lake Como Hotel or Similar, Cernobbio, Royal Victoria Varenna Lake Como Hotel or Similar, Venice, Hilton Molino Stucky or Similar, Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Messina, Taormina, Sorrento, Civitavecchia, Rome
2027 Sails: May 13, Jul 13, Oct 2, More...
Avalon Vista Tours11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: May 18, Jun 1, Jun 15, Jun 29, Jul 13, Jul 27, Aug 10, Aug 24, Sep 7, Sep 21, Oct 5, Oct 19, Nov 2, 2028: Mar 7, Mar 21, Apr 4, Apr 18, May 2, May 16, Sep 5, More...
Star Explorer Tours11 Night - Lake Como & Adriatic Romance Cruise Tour
Starting in Royal Victoria Varenna Lake Como Hotel or Similar, Cernobbio, Royal Victoria Varenna Lake Como Hotel or Similar, Venice, Hilton Molino Stucky or Similar, Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Taormina, Sorrento, Civitavecchia, Rome
2027 Sails: Sep 28, Oct 14, More...
Avalon Envision Tours11 Night - Christmastime On the Romantic Rhine with in Lake Como, in Lucerne with Swiss Alps (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen / Heidelberg Excursion, Rudesheim / Rhine Gorge, Cologne, Germany, Mainz, Frankfurt (Disembarkation)
2027 Sails: Nov 26, Dec 10, More...
Star Explorer Tours11 Night - Lake Como & Adriatic Romance Cruise Tour
Starting in Royal Victoria Varenna Lake Como Hotel or Similar, Cernobbio, Royal Victoria Varenna Lake Como Hotel or Similar, Venice, Hilton Molino Stucky or Similar, Venice, Rovinj, Split, Dubrovnik, Croatia, Kotor, Giardini Naxos, Taormina, Sorrento, Civitavecchia, Rome
2028 Sails: Apr 7, Oct 2, More...
Avalon Panorama Tours11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2028 Sails: May 9, May 23, Jun 6, Jul 4, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, Oct 24, Nov 7, More...


Lake Como Cruise Departures