Rome Cruise Departures

Cruises that depart from Mediterranean: Italy: Rome

Cruises that visit Rome

Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.

16 Night - Star Collector : Winter in Spain and the Rivieras
Starting in Rome, Livorno, Genoa, Italy, Nice, Barcelona, Valencia, Cartagena ES, Gibraltar, Malaga, Palma De Mallorca, Barcelona
2026 Sails: Feb 20, More...

Windstar, Star Legend

7 Night - Europe's Winter Riviera
Starting in Rome, Livorno, Genoa, Italy, Nice, Barcelona
2026 Sails: Feb 20, 2027: Nov 5, More...

Viking Ocean, Viking Vesta

7 Night - Iconic Western Mediterranean
Starting in Rome (Civitavecchia), Florence / Pisa (Livorno), Villefranche-Sur-Mer, Marseille, Sete, Barcelona
2026 Sails: Mar 6, More...

Windstar, Star Legend

8 Night - Winter Italy and the Dalmatian Coast
Starting in Rome, Naples, Messina (Taormina), Dubrovnik, Croatia, Zadar, Venice
2026 Sails: Mar 15, More...

Windstar, Star Legend

8 Night - Winter in Italy and the Adriatic
Starting in Rome, Naples, Catania, Crotone, Italy, Corfu (Kerkyra), Delphi, Corinth Canal, Athens, Greece
2026 Sails: Mar 31, More...

Viking Ocean, Viking Vesta

7 Night - Journey to Antiquities
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Sail the Ionian Sea, Crete (Souda Bay), Ephesus (Kusadasi), Athens (Piraeus)
2026 Sails: Apr 4, More...

Viking Ocean, Viking Jupiter

Azamara Cruises, Azamara Journey

11 Night - France Intensive Cruise : Mysteries & Lore
Starting in Rome (Civitavecchia), Bonifacio, Cannes, Monte Carlo, Sete, Sanary-sur-mer, Provence (Marseille), St Tropez, Menton, Nice
2026 Sails: Apr 17, More...

Regent Seven Seas, Seven Seas Voyager

9 Night - Pesto, Paella & Paradise
Starting in Rome (Civitavecchia), Portoferraio (Elba Island), La Spezia (Cinque Terre), Villefranche, Cruising the Balearic Sea, Alicante, Valencia, Ibiza, Barcelona (Tarragona)
2026 Sails: Apr 17, More...

Viking Ocean, Viking Sea

7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Apr 19, More...

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