Rome Cruise Departures
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
10 Night - Mediterranean Medley
Starting in Rome (Civitavecchia), Salerno, Taormina (Sicily), Valletta, Ibiza, Valencia, Barcelona, Provence (Marseille), Cannes, Monte Carlo
2026 Sails: Jul 2, More...
7 Night - Western Mediterranean Cruise
Starting in Rome (Civitavecchia), Italy, Provence (Marseille), France, Barcelona, Spain, Palma De Mallorca, Spain, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 4, More...
7 Night - Greek Isles Cruise
Starting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, More...
11 Night - Greece, Turkey & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 6, Jul 27, Sep 7, Sep 28, More...
7 Night - Greek Isles & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Sicily (Messina), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Jul 6, Sep 28, More...
8 Night - Bella Italia - a Southern Italian Romance
Starting in Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice
2026 Sails: Jul 7, More...
10 Night - Tuscan Summer
Starting in Rome (Civitavecchia), Tuscany (Livorno), Toulon, Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Malaga, Gibraltar, Cruising the Atlantic Ocean, Portimao, Lisbon
2026 Sails: Jul 10, More...7 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 11, More...10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Dubrovnik, Croatia, Split, Croatia, Montenegro, Corfu, Greece, Olympia (Katakolon), Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 17, Oct 9, More...7 Night - Western Mediterranean
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Provence (Marseille), France, Palma De Mallorca, Spain, Barcelona, Spain, Rome (Civitavecchia), Italy
2026 Sails: Jul 18, More...
Cruises that depart from Mediterranean: Italy: Rome
Cruises that visit Rome
See all River Cruises that depart from Rome
Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.
10 Night - Mediterranean MedleyStarting in Rome (Civitavecchia), Salerno, Taormina (Sicily), Valletta, Ibiza, Valencia, Barcelona, Provence (Marseille), Cannes, Monte Carlo
2026 Sails: Jul 2, More...
7 Night - Western Mediterranean CruiseStarting in Rome (Civitavecchia), Italy, Provence (Marseille), France, Barcelona, Spain, Palma De Mallorca, Spain, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 4, More...
7 Night - Greek Isles CruiseStarting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, Sep 20, Sep 27, Oct 4, More...
11 Night - Greece, Turkey & Italy CruiseStarting in Rome (Civitavecchia), Italy, Chania (Souda), Crete, Greece, Santorini, Greece, Ephesus (Kusadasi), Turkey, Istanbul, Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 6, Jul 27, Sep 7, Sep 28, More...
7 Night - Greek Isles & Italy CruiseStarting in Rome (Civitavecchia), Italy, Naples, Italy, Sicily (Messina), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Athens (Piraeus), Greece
2026 Sails: Jul 6, Sep 28, More...
8 Night - Bella Italia - a Southern Italian RomanceStarting in Rome, Amalfi, Marina Velentia (Vibo Valentia), Italy, Reggio Calabria, Italy, Taranto, Italy, Otranto, Italy, Rab, Croatia, Venice
2026 Sails: Jul 7, More...
10 Night - Tuscan SummerStarting in Rome (Civitavecchia), Tuscany (Livorno), Toulon, Barcelona, Palma De Mallorca, Cruising the Mediterranean Sea, Malaga, Gibraltar, Cruising the Atlantic Ocean, Portimao, Lisbon
2026 Sails: Jul 10, More...
7 Night - Western MediterraneanStarting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 11, More...
10 Night - Italy, Greece & Croatia CruiseStarting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Dubrovnik, Croatia, Split, Croatia, Montenegro, Corfu, Greece, Olympia (Katakolon), Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Jul 17, Oct 9, More...
7 Night - Western MediterraneanStarting in Rome (Civitavecchia), Italy, Naples, Italy, Provence (Marseille), France, Palma De Mallorca, Spain, Barcelona, Spain, Rome (Civitavecchia), Italy
2026 Sails: Jul 18, More...
