CruiseCompete.com
Travel Agents Competing To Offer The Best Cruise Deals
1
Find your cruise
& request quotes
2
Compare personalized offers
prices, upgrades, cabin credits & more
3
Contact your preferred agent
for questions or to book your cruise
Trusted by more than 1.5 million consumers since 2003.
Join Now
Rome Cruise Departures

Cruises that depart from Mediterranean: Italy: Rome

Cruises that visit Rome

See all River Cruises that depart from Rome

Click on a cruise ship itinerary sailing from Rome (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Rome), please visit: Cruise Search or try our Virtual Cruise Advisor™.



Royal Caribbean, Legend of the Seas
Legend of the Seas7 Night - Western Mediterranean Cruise
Starting in Rome (Civitavecchia), Italy, Naples, Italy, Barcelona, Spain, Palma De Mallorca, Spain, Provence (Marseille), France, Florence / Pisa (La Spezia), Italy, Rome (Civitavecchia), Italy
2026 Sails: Oct 1, Oct 8, Oct 15, More...
Viking Ocean, Viking Neptune
Viking Neptune7 Night - Italian Sojourn
Starting in Rome (Civitavecchia), Naples, Sicily (Messina), Crotone, Bari, Sibenik, Venice (Fusina)
2026 Sails: Oct 3, 2027: Sep 4, More...
Royal Caribbean, Odyssey of the Seas
Odyssey of the Seas7 Night - Greek Isles Cruise
Starting in Rome (Civitavecchia), Italy, Santorini, Greece, Ephesus (Kusadasi), Turkey, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Oct 4, More...
Celebrity Cruises, Celebrity Ascent
Celebrity Ascent10 Night - Italy, Greece & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Dubrovnik, Croatia, Split, Croatia, Montenegro, Corfu, Greece, Olympia (Katakolon), Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Oct 9, More...
Regent Seven Seas, Seven Seas Voyager
Seven Seas Voyager7 Night - Spotlight On Sparkling Wines
Starting in Rome (Civitavecchia), Naples / Pompeii, Messina (Sicily), Valletta, Cruising the Adriatic Sea, Dubrovnik, Croatia, Zadar, Venice (Fusina)
2026 Sails: Oct 10, More...
Royal Caribbean, Odyssey of the Seas
Odyssey of the Seas7 Night - Greek Isles & Italy Cruise
Starting in Rome (Civitavecchia), Italy, Sicily (Messina), Italy, Santorini, Greece, Mykonos, Greece, Naples, Italy, Rome (Civitavecchia), Italy
2026 Sails: Oct 11, Oct 18, More...
Celebrity Cruises, Celebrity Constellation
Celebrity Constellation11 Night - Best of Italy & Croatia Cruise
Starting in Rome (Civitavecchia), Italy, Florence / Pisa (Livorno), Italy, Amalfi Coast (Salerno), Italy, Sicily (Messina), Italy, Kotor, Montenegro, Brindisi, Italy, Split, Croatia, Zadar, Croatia, Ravenna, Italy
2026 Sails: Oct 12, More...
Oceania Cruises, Oceania Sirena
Oceania Sirena7 Night - Balearic & Riviera Resorts
Starting in Rome (Civitavecchia), Florence / Pisa / Tuscany (Livorno), Porto Torres (Sardinia), Mahon (Menorca), Barcelona, Sete, Toulon, Monte Carlo
2026 Sails: Oct 12, More...
Ritz-Carlton, Evrima
Evrima5 Night - Rome (Civitavecchia) / Monte Carlo
Starting in Rome (Civitavecchia), Portoferraio, Elba, Livorno, Portofino, Saint-Tropez, Monte Carlo
2026 Sails: Oct 12, More...
Ritz-Carlton, Ilma
Ilma7 Night - Rome (Civitavecchia) / Barcelona
Starting in Rome (Civitavecchia), Livorno, Monte Carlo, Saint-Tropez, Palma de Mallorca, Mallorca, Balearic Islands, Barcelona
2026 Sails: Oct 13, More...

More =>

Rome Cruise Departures