Italy River Cruise Departures
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
Italy Coast Cruises
River cruises by river name
Related areas: Lake Como : Milan : Perugia : Rome : Taormina : Venice
7 Night - Venice & the Jewels of Veneto
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2026 Sails: Oct 4, Oct 11, Oct 25, Nov 1, 2027: Apr 11, Apr 18, Apr 25, May 2, May 9, May 16, May 23, May 30, Jun 6, Jun 13, Jun 20, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, More...
14 Night - Grand Tour of the Heart of Italy to Portugal's Douro Valley Cruise
Starting in Perugia, Italy, Umbria, Italy, Spoleto, Italy, Marche, Italy, Orvieto, Italy, Porto, Portugal, Pinhao, Portugal, Castelo Rodrigo, Portugal, Salamanca, Spain, Mateus Palace, Portugal, Lamego, Portugal, Porto, Portugal
2026 Sails: Oct 8, 2027: Jul 1, Aug 19, Aug 26, Sep 30, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Oct 27, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Nov 6, More...11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Nov 6, Dec 4, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, Apr 14, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, More...18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 29, Oct 13, Oct 27, More...11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Apr 2, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 20, Sep 17, Oct 15, Oct 29, Nov 12, 2028: Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Jun 30, Aug 11, Aug 25, Sep 8, Sep 22, More...18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Apr 2, May 14, May 28, Jun 25, Jul 9, Jul 23, Aug 20, Oct 15, Oct 29, 2028: Apr 7, May 5, May 19, Jun 2, Jun 30, Aug 11, Aug 25, Sep 8, Oct 6, Oct 20, Nov 3, More...18 Night - Cruise & Tour : Experience the Best of Italy
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Rome via High-Speed Train, Rome (Vatican City), Rome, Pompeii, Capri or Sorrento, Capri (or Sorrento), Capri, Assisi, Perugia, Perugia, San Gimignano, Florence, Florence, Florence, Pisa, Rapallo, Rapallo (Cinque Terre), Rapallo, Venice, Venice, Venice (Depart)
2027 Sails: Apr 25, May 2, May 9, May 16, May 30, Jun 6, Jun 27, Jul 11, Aug 29, Sep 5, Sep 12, Sep 19, Sep 26, Oct 3, More...
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
Italy Coast Cruises
Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Lake Como : Milan : Perugia : Rome : Taormina : Venice
7 Night - Venice & the Jewels of VenetoStarting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2026 Sails: Oct 4, Oct 11, Oct 25, Nov 1, 2027: Apr 11, Apr 18, Apr 25, May 2, May 9, May 16, May 23, May 30, Jun 6, Jun 13, Jun 20, Jun 27, Jul 4, Jul 11, Jul 18, Jul 25, Aug 1, Aug 8, Aug 15, Aug 22, More...
14 Night - Grand Tour of the Heart of Italy to Portugal's Douro Valley CruiseStarting in Perugia, Italy, Umbria, Italy, Spoleto, Italy, Marche, Italy, Orvieto, Italy, Porto, Portugal, Pinhao, Portugal, Castelo Rodrigo, Portugal, Salamanca, Spain, Mateus Palace, Portugal, Lamego, Portugal, Porto, Portugal
2026 Sails: Oct 8, 2027: Jul 1, Aug 19, Aug 26, Sep 30, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Oct 27, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Nov 6, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Nov 6, Dec 4, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, Apr 14, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 15, Sep 29, Oct 13, Oct 27, Nov 10, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Mar 26, Apr 9, May 7, Jul 16, Jul 30, 2028: Mar 31, May 12, Jul 7, Jul 21, Aug 4, Aug 18, Sep 1, Sep 29, Oct 13, Oct 27, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation)
2027 Sails: Apr 2, Apr 30, May 14, May 28, Jun 11, Jun 25, Jul 9, Jul 23, Aug 20, Sep 17, Oct 15, Oct 29, Nov 12, 2028: Apr 7, Apr 21, May 5, May 19, Jun 2, Jun 16, Jun 30, Aug 11, Aug 25, Sep 8, Sep 22, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Ludwigshafen, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, the Netherlands, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2027 Sails: Apr 2, May 14, May 28, Jun 25, Jul 9, Jul 23, Aug 20, Oct 15, Oct 29, 2028: Apr 7, May 5, May 19, Jun 2, Jun 30, Aug 11, Aug 25, Sep 8, Oct 6, Oct 20, Nov 3, More...
18 Night - Cruise & Tour : Experience the Best of ItalyStarting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Rome via High-Speed Train, Rome (Vatican City), Rome, Pompeii, Capri or Sorrento, Capri (or Sorrento), Capri, Assisi, Perugia, Perugia, San Gimignano, Florence, Florence, Florence, Pisa, Rapallo, Rapallo (Cinque Terre), Rapallo, Venice, Venice, Venice (Depart)
2027 Sails: Apr 25, May 2, May 9, May 16, May 30, Jun 6, Jun 27, Jul 11, Aug 29, Sep 5, Sep 12, Sep 19, Sep 26, Oct 3, More...
