Italy River Cruise Departures
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
River cruises by river name
Related areas: Lake Como : Milan : Venice
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Mar 19, Apr 2, Apr 16, Apr 30, May 14, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Mar 31, Apr 28, May 12, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 15, Sep 29, Oct 13, Oct 27, More...
7 Night - Venice & the Jewels of Veneto
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2026 Sails: Apr 5, Apr 12, Apr 19, Apr 26, May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, More...10 Night - Rome, Venice & the Jewels of Veneto
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Rome, Rome
2026 Sails: Apr 5, Apr 12, Apr 19, Apr 26, May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jul 12, Jul 19, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 11, Oct 25, More...16 Night - Cruise & Rail : Venice, Istanbul & the Balkans
Starting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Ljubljana, Sarajevo, Mostar, Belgrade, Podgorica, Skopje, Sofia, Plovdiv, Istanbul
2026 Sails: May 3, Aug 23, Sep 27, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 8, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Sep 11, Oct 9, Oct 23, Nov 6, Nov 20, Dec 4, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-Cruise
Starting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 19, Oct 3, Oct 17, More...25 Night - Vineyards, Chateaux & Bordeaux with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation) Bordeaux (Embarkation), Bordeaux / Pauillac, Cussac Fort Medoc, Blaye / Bourg, Libourne Excursion to Saint-emilion, Bordeaux, Bordeaux Excursion to Arcachons Bay, Bordeaux (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Aug 28, Oct 9, More...18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in Lucerne
Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Oct 9, Oct 23, Nov 6, More...
River Cruises that depart from Mediterranean: Italy
River Cruises that visit Italy
See all Cruises that depart from Italy
Click on a cruise ship itinerary sailing from Italy (below) and select a sail date to receive competing cruise quotes. To search all cruise itineraries (not just Italy), please visit: Cruise Search or try our Virtual Cruise Advisor™.
River cruises by river name
Related areas: Lake Como : Milan : Venice
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: Mar 19, Apr 2, Apr 16, Apr 30, May 14, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: Mar 31, Apr 28, May 12, Jun 9, Jun 23, Jul 7, Jul 21, Aug 4, Aug 18, Sep 15, Sep 29, Oct 13, Oct 27, More...
7 Night - Venice & the Jewels of VenetoStarting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice
2026 Sails: Apr 5, Apr 12, Apr 19, Apr 26, May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jun 28, Jul 5, Jul 12, Jul 19, Jul 26, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 6, Sep 13, More...
10 Night - Rome, Venice & the Jewels of VenetoStarting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Rome, Rome
2026 Sails: Apr 5, Apr 12, Apr 19, Apr 26, May 3, May 10, May 17, May 24, May 31, Jun 7, Jun 14, Jun 21, Jul 12, Jul 19, Aug 2, Aug 9, Aug 16, Aug 23, Aug 30, Sep 13, Sep 20, Sep 27, Oct 11, Oct 25, More...
16 Night - Cruise & Rail : Venice, Istanbul & the BalkansStarting in Venice, Venice (Padua), Mazzorbo (Burano), Mazzorbo, Burano, Chioggia, Chioggia, Chioggia, Venice, Venice, Venice, Transfer to Train, Trieste, Postojna, Ljubljana, Sarajevo, Mostar, Belgrade, Podgorica, Skopje, Sofia, Plovdiv, Istanbul
2026 Sails: May 3, Aug 23, Sep 27, More...
11 Night - Romantic Rhine with Swiss Alps, in Lake Como & in Lucerne (Northbound)Starting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation)
2026 Sails: May 8, Jun 5, Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Sep 11, Oct 9, Oct 23, Nov 6, Nov 20, Dec 4, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 9, May 23, Jun 6, Jun 20, Jul 4, Jul 18, Aug 1, Aug 15, Aug 29, Sep 12, Sep 26, Oct 10, More...
10 Night - Swiss Alps & Rhine Castles with Lake Como Pre-CruiseStarting in Lake Como, Lucerne, Basel, Strasbourg, Ludwigshafen, Rudesheim, Rhine Gorge, Lahnstein, Cologne, Amsterdam
2026 Sails: May 16, May 30, Jun 13, Jun 27, Jul 11, Jul 25, Aug 8, Aug 22, Sep 19, Oct 3, Oct 17, More...
25 Night - Vineyards, Chateaux & Bordeaux with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation) Bordeaux (Embarkation), Bordeaux / Pauillac, Cussac Fort Medoc, Blaye / Bourg, Libourne Excursion to Saint-emilion, Bordeaux, Bordeaux Excursion to Arcachons Bay, Bordeaux (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Aug 28, Oct 9, More...
18 Night - Timeless Rivers of Europe : the Rhine and Seine with Swiss Alps, in Lake Como & in LucerneStarting in Lake Como, Italy, Lake Como, Lake Como / Lucerne, Switzerland, Lucerne / Swiss Alps / Basel (Embarkation), Breisach, Germany Excursion to Black Forest, Kehl Excursion to Strasbourg, France, Mainz, Germany Excursion to Heidelberg, Rudesheim / Rhine Gorge, Cologne, Amsterdam, Holland, Amsterdam (Disembarkation) Paris, France (Embarkation), Vernon, Caudebec, Caudebec Excursion to Normandy, Rouen, Conflans, Paris, Paris (Disembarkation)
2026 Sails: Jun 19, Jul 3, Jul 17, Jul 31, Aug 28, Oct 9, Oct 23, Nov 6, More...
